Intriguing functions for GBP5, ascribing it a broad immunoregulatory role during inflammation. 💥 Thanks to all collaborators and our funding sources! 🙏

Hot off the biorxiv press! 🔥 Samuel Lara-Reyna finds GBP5 enhances macrophage glycolysis via glucose uptake, GTPase activity dependent and as being cis-Golgi localised. Bonus finding, GBP5 is important for full M1 macrophage functionality.
www.biorxiv.org/content/10.6...

Check out this new paper by @avishenoy.bsky.social lab - GBP1 can detect extracellular bacteria from the inside of cells! 😎 LPS solubilisation, Toxoplasma vacuole disruption and now immunity through actin binding - what a superpower protein! 😬 Happy to have supported this project!

Thanks Jeroen! 🙏 I’m excited and ready to contribute some cool science again! 🤩

Thanks to Dominique Soldati, the Department and the Wellcome Trust for enabling this move! (5/5)

If you’re less than 1 year post-PhD in Immunology/Cell Biology/Molecular Biology, contact me e.frickel@bham.ac.uk to discuss. (4/5)

Embed your project in a dynamic, friendly, and international environment. Most importantly, be bold and curious! (3/5)

The open projects will build on our findings to delineate novel pathways of host responses in infected cells and their utility in uninfected bystander cells. (2/5)

🔥 Open postdoc position in human inflammation-driven control of infection! 🔥
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)

Please share!

And this is it. It’s the Christmas message. Live in the moment, do the big stuff you think you can’t do now, enjoy what you have and eat the chocolate with the kids.

“It’s made us live more in the moment and that’s our mentality now: if we ever feel like doing something with the children, we do it. We just let them have the chocolate buttons.”

From the article: Losing Alexander and Isabelle has opened her eyes to what’s important in life. “You try to make the best of life after your child dies, but it’s never the same again,” she says.

Two years after our toddler’s sudden death, our world collapsed again When Emily Cooper’s son died aged three, tests showed she and her husband had a genetic mutation endangering their other children

Read this important piece about child loss due to under researched genetic mutations that stole @criminographer.bsky.social Alexander and Isabelle. www.thetimes.com/uk/healthcar...

Tune into #inflammazoom in 45min!

I’m liking the new energy on this platform. I’ve sat on the scientific sidelines for some of this year, while we as a family are re-grouping after losing Leo aged 4 in ‘22 and Alby aged 1 month in ‘23. I’m grateful for so many supportive colleagues out there. Science is a wonderful place.

Hi Ali! Please add me, thanks!