Delighted to share our discoveries about one of the brain's neurotransmitter systems:
www.biorxiv.org/content/10.6...
Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
Eager to learn how one shanks a P10 rat with a neuropixels
Very cool stuff
(sorry)
alpenglow!
1) Why is this the first I’m learning about fish talking to each other by slapping their bellies
2) The actual results in this paper are awesome
how a small (~15) prolific and opinionated set of reviewers could steer a field over time
This is great, and even these numbers underestimate the effect. Some fields have <10 qualified reviewers, one loud voice can tank or lift papers on its own
Our perspectives piece on Agentic AI for biomedical research has been published in Nature Biotechnology www.nature.com/articles/s41... #agenticAI #artificialintelligence #agents
Science has now published our eLetter responding to Rajendran et al., titled, “Data show that macaques do not synchronize to a beat”
doi.org/10.1126/scie...
For all the energy we use in developing new technologies and fancier data handling, this is an immediate, actionable problem that we need to prioritize
Beautifully written!
New lab preprint! Can we study conscious perception of gut sensations in mice to reveal its neuronal basis? Can we train mice to report their gut sensations? Omer Rafael and Stav Shtiglitz in the lab teamed up to discover that…YES! Thread…1/6 www.biorxiv.org/content/10.6...
Almost feels wrong to see suite2p as a paper after all these years, used to it being a more of a silent pillar
What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
lab preprint! Interopceptive predictions are central to many brain-body interactions theories, but it's unclear if/how they affect bodily physiology. We (fearless Einav Litvak et al) show that insular cortex predictions are essential for glucose homeostasis-THREAD.. www.biorxiv.org/content/10.6...
We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect.
The full study is now online at Cell. @cp-cell.bsky.social
Paper 👉 www.cell.com/cell/fulltex...
Thread for a synopsis 👉
bsky.app/profile/alex...
In @thetransmitter.bsky.social’s Rising Stars of Neuroscience 2025, we recognize 25 early-career researchers who have made outstanding scientific contributions and demonstrated a commitment to mentoring and community-building in neuroscience.
#neuroskyence #StateOfNeuroscience
bit.ly/4rnFnyQ
Gracias Carlos!! Nos vemos en opto GRC o neuromodulation GRC estos años?
thank you Anne, I miss Duke but at least i still have like 10 neurobio Dukies here (:
great to hear from you Cam! come visit us
not easy to take a picture of a transparent object
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.
Wonderful list of people: www.thetransmitter.org/early-career...
Woulda guessed 50%, glass half full kinda person
Seems we have to lean on operationalizing for a lot of animal work.
How would you propose to improve on this e.g for the rodent attention or fly sleep task you mentioned?
ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS
Comment period ends September 29th
www.federalregister.gov/documents/20...
1/2
You also haven’t heard of those famous giant voxel axon recordings
huzzah!!
Awesome Kiah!! Congrats and I’m looking forward to reading this
being wrong is ok
Hah If it makes you feel better comp sci and theory people are just as guilty of these mistakes
Each of the types of papers
in this list are useful in their own right, just a tongue in cheek comment :)
the explosion of any technique inevitably brings an avalanche of papers that misuse, over-claim, or rediscover things.
4. I don’t give a shit what it is, we sequenced it and splattered it on a umap, nothing changed but now we have art
