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Posts by Andrea Zingaro

Last week we brought #IRBPhDDay2025 to life at @irbbarcelona.org.

Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.

Thank you to all who made it possible!

5 months ago 2 0 0 0
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The 2nd #IRBBarcelona #PhD Day has been a great success. A huge thank you to all participants & speakers! Special congrats to our best speakers:

๐—š๐—ถ๐—ฎ๐—ฐ๐—ผ๐—บ๐—ผ ๐— ๐˜‚๐˜๐˜๐—ถ-Long Talk
๐—ฉ๐—ฎ๐—น๐—ฒ๐—ป๐˜๐—ถ๐—ป ๐—ฃ๐—น๐—ฒ๐˜๐—ฒ๐—ฎ & ๐—Ÿ๐˜‚๐—ถ๐˜€ ๐—ก๐—ถ๐—ฒ๐˜๐—ผ ๐—•๐—ฎ๐—ฟ๐—ฟ๐—ฎ๐—ฑ๐—ผ-Flash Talks
๐—ž๐—ฎ๐˜‚๐˜€๐˜๐˜‚๐˜ƒ ๐—š๐—ต๐—ผ๐˜€๐—ต & ๐— ๐—ฎ๐—ฟ๐˜๐—ถฬ ๐—ฆ๐—ถ๐—ฑ๐—ฟ๐—ผ ๐—œ๐—ป๐—ด๐—น๐—ฒฬ๐˜€-Short Talks
๐—š๐—ถ๐˜‚๐—น๐—ถ๐—ฎ ๐—ฉ๐—ถ๐—ผ๐—น๐—ฎ-Poster Session

5 months ago 3 1 0 1
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๐Ÿค—Here are some highlights from this #OpenDayIRB25 morning with families!
๐Ÿ”ŽDiscoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda รlvaro and @thecrabapple.bsky.social ๐ŸŽถ

10 months ago 7 3 0 0
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โœจ Get ready to be inspired at the #IRBBarcelona #OpenDay!

๐ŸŽฏ Save the date!

๐Ÿ—“๏ธ Saturday, May 24
Morning = family fun ๐Ÿ‘จโ€๐Ÿ‘ฉโ€๐Ÿ‘งโ€๐Ÿ‘ฆ
Afternoon = deep science dive ๐Ÿ”

Sign up here! ๐Ÿ”— bit.ly/3Z1wf6b

#ScienceForEveryone

๐Ÿงช

11 months ago 7 4 1 0
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Why biotech is booming in Barcelona World-class research institutes and university hospitals, a culture of groundbreaking science and a thriving investment ecosystem make Barcelona a rising star in the life sciences industry, as these t...

"Investment in Barcelonaโ€™s biotech sector is also booming, with international investors increasingly seeing the city as a potential hotbed for therapeutic breakthroughs"

11 months ago 14 2 1 0
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Small-molecule RNA therapeutics to target prostate cancer Kuzuoglu-Ozturk etย al. showcase a therapeutic approach, โ€œtranslatome therapy,โ€ to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1ฮฑ through remodeling their 5โ€ฒ UTR RNA structure. Zotatifin enhances anti-androgen and radiotherapy sensitivity, highlighting a promising anti-cancer treatment.

Online Now: Kuzuoglu-Ozturk etย al. showcase a therapeutic approach, โ€œtranslatome therapy,โ€ to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1ฮฑ throughโ€ฆ

1 year ago 2 2 0 0
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๐ŸŸฃ On #WomensDay, we recognize the incredible women of #IRBBarcelona! Researchers, technicians, managers, and other professionals whose talent and dedication push the boundaries of knowledge.

Your work fuels discovery and paves the way for future generations of women in science.

Thank you! ๐Ÿ™Œ

#8M

1 year ago 64 17 0 0
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Remodelling of the translatome controls diet and its impact on tumorigenesis - Nature During fasting, hepatocytes selectively remodel the translatome while global translation is downregulated, showing a new signalling property of fatty acids and that, on a ketogenic diet, treatment wit...

Excited to share that our research has been published in @nature.com
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:

1 year ago 3 0 0 0
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Functional screen identifies RBM42 as a mediator of oncogenic mRNA translation specificity - Nature Cell Biology Kovalski et al. perform a genome-wide CRISPRi screen for selective MYC mRNA translation regulators and identify RBM42 as a ribosome-associated protein that modulates translation of MYC and an oncogeni...
1 year ago 2 0 0 0
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๐Ÿซง๐Ÿ”Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.

๐Ÿ’ŠThe study opens new avenues for the development of targeted treatments for autism.

๐Ÿ“ฐ Nature @natureportfolio.bsky.social

โœ๏ธ Carla Garcia-Cabau, Anna Bartomeu et al.

โžก๏ธ bit.ly/3BfEGlR

๐Ÿ“Œ DOI: 10.1038/s41586-024-08289-w

1 year ago 28 16 2 4