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Posts by The Rachel O'Reilly group

Congratulations @pikramenougroup.bsky.social !!!

5 days ago 0 0 0 0
Professor Anna Peacock named EuroBIC Medal recipient for 2026 - University of Birmingham The award recognises outstanding young scientists working in bioinorganic chemistry in Europe.

Congratulations to @peacockgroup.bsky.social on Anna's award of the 2026 EuroBIC Medal! Truly well deserved recognition! @uobchemistry.bsky.social #chemsky
www.birmingham.ac.uk/news/2026/pr...

3 weeks ago 3 0 0 0
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We have a fully funded PhD position (UK students only) at @uobchemistry.bsky.social to work on #multiscale #modelling and #ML of organic #materials! Details www.grynova-ccc.org/jobs.html #chemsky #PhDjobs #chemPhD Please spread the word!

1 month ago 13 9 0 0
Ultrasound-activated ‘nanoagents’ kill superbugs in biofilms - University of Birmingham New ‘nanoagents’ can carry drugs straight to infected areas with minimal amounts of drug - reducing the risks of antibiotic resistance.

Check out the press release for our publication pubs.acs.org/doi/10.1021/... @jacsau.bsky.social on new nanoagents triggered by ultrasound to deliver antibiotics deep in biofilms www.birmingham.ac.uk/news/2026/ul...

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Prof. Rachel O'Reilly in the Aston Webb Main Lecture Hall

Prof. Rachel O'Reilly in the Aston Webb Main Lecture Hall

Rachel delivered a Showcase Lecture to UoB UG and PG students, postdocs and staff on 24 February 2026, organised by Chemistry Yr 4 UG students Eliza Eng and Ed Bennett.
@uobchemistry.bsky.social Photo by @tianlaixia.bsky.social

1 month ago 2 1 0 0
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A perfluoro-functionalised fluorescent maleimide probe for imaging of per- and polyfluoroalkyl substances - Environmental Chemistry Letters The persistence of per- and polyfluoroalkyl substances in the environment is becoming a major health concern, yet studying their fate and behaviour in complex media is limited due to the lack of suita...

Congratulations to former ROR Group members Jake Barker, @stephenfielden.bsky.social, @ctjferguson.bsky.social reporting synthesis of a fluorescent PFAS probe—enabling detection of persistent PFAS in the environment: link.springer.com/article/10.1...
#maleimides #chemsky @uobchemistry.bsky.social

2 months ago 2 2 0 0
A palindromic triplex architecture for DNA-templated synthesis designed for the core of a synthetic ribosome We demonstrate a triplex-based architecture for DNA-templated synthesis. This study is motivated by progress towards the development of a synthetic ribosome – autonomous, genetically programmable, molecular machinery for synthesis. Such schemes for the creation and evolution of chemically diverse DNA-tagged chemica

Rachel and @kavlioxford.bsky.social introduce a triplex-based DNA templated synthesis architecture: enabling flexible, parallel one pot incorporation of any building block at any position. pubs.rsc.org/en/content/a...
@uobchemistry.bsky.social @polymerchem.rsc.org
#chemsky #polymers

2 months ago 2 1 0 0
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Photo-initiated solvent-mediated depolymerization of consumer poly(methyl methacrylate) without chlorinated reagents - Nature Communications Chemical recycling of poly(methyl methacrylate) (PMMA) typically requires high temperatures. Here, the authors report the UV-initiated depolymerisation of PMMA at low temperatures, in non-chlorinated ...

It's finally out! Our work showing we can use light to do recycling of plastics at much lower temperatures than currently done at scale. The technology shows promise as it might be able to deal with mixed plastic waste, which currently can't be recycled. www.nature.com/articles/s41... #recycling

2 months ago 2 1 0 0
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Women in Photochemistry Symposium 2026 Join us for an afternoon of inspiring talks and networking at the Women in Photochemistry Symposium!

My colleague Helen Fielding is organising the 2026 Women in Photochemistry Symposium at @uclchemistry.bsky.social on Wednesday the 4th of March with talks by Susannah-Bourne-Worster (Durham), Maria Sanz (King's College) and Marsha Lester (UPenn).

www.eventbrite.co.uk/e/women-in-p...

#chemsky

2 months ago 10 7 1 0
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And the most recent #JournalClub on interpreting the #PXRD patterns of covalent organic #frameworks #COF by @mollart.bsky.social based on Lotsch group’s paper www.grynova-ccc.org/journal-club...

2 months ago 4 3 0 0
University of Birmingham appoints globally renowned life sciences experts - University of Birmingham Two internationally renowned experts are coming to Birmingham as part of a Government drive to attract global research talent to the UK.

Great news for UoB and for me @johnmlindner.bsky.social www.birmingham.ac.uk/news/2026/un...

2 months ago 4 1 0 0
Rachel O'Reilly presenting during the McBain Medal symposium honouring Gemma Louise Davies January 2026.

Rachel O'Reilly presenting during the McBain Medal symposium honouring Gemma Louise Davies January 2026.

Congratulations @gemmaloudavies.bsky.social on the award of the McBain Medal 2025 for outstanding achievement in colloid and interface science! During the full-day meeting, Rachel O'Reilly spoke on 'precision polymer nanoparticles'. @uobchemistry.bsky.social

2 months ago 2 0 0 0
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NIR-Actuated Morphodynamic 2D Nanopatches for Interface-Programmed Immunoactivation and Tumor Regression Achieving precise spatiotemporal modulation of immunostimulatory effects remains a fundamental barrier in tumor immunotherapy, particularly in the context of limited tumor antigen exposure and an immunosuppressive microenvironment. Herein, we present a light-responsive “dynamic nanopatch” platform that addresses these challenges through morphology-directed and interface-programmed immunoactivation. Constructed from crystalline poly(ε-caprolactone) and integrated with photothermal conversion elements, the nanopatch undergoes a near-infrared (NIR)-triggered morphology-dynamic transition from a two-dimensional planar structure to a zero-dimensional spherical counterpart. This dynamic structural transformation enables programmable interactions with the cellular membrane, establishing a versatile nanointerface capable of the in situ regulation of cancer cell membrane integrity. Upon NIR irradiation, the nanopatch stably adheres to the tumor cell surface and initiates a cascade of adhesion, deformation, and internalization events. This process promotes localized mechanical stress and membrane perturbation, enhancing the release of tumor-associated antigens and damage-associated molecular patterns, which collectively initiate potent immunogenic cell death. Subsequent activation of antigen-presenting cells leads to robust adaptive immune engagement and amplified immune cell infiltration within the tumor microenvironment. This morphodynamic nanopatch offers a highly controllable strategy for cancer immunotherapy and a new paradigm for interface-programmed functionalities with broad implications for precision medicine, immunotherapy, and biomaterial engineering.

ROR group @uobchemistry.bsky.social and researchers at Shanghai and Zhejiang Sci-Tech universities develop a light-activated “nanopatch” that sticks to tumour cells and stresses their membranes, also promoting the release of antigens: pubs.acs.org/doi/full/10....
@tianlaixia.bsky.social
#Chemsky

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