FDA Fast Track for BBOT’s BBO-11818 in Pancreatic Cancer BBOT receives U.S. FDA Fast Track Designation for BBO-11818, its pan-KRAS inhibitor for advanced KRAS-mutant pancreatic cancer. Phase 1 data expected H2 2026.

$BBOT +7% [BBOT receives U.S. FDA Fast Track Designation for BBO-11818, its pan-KRAS inhibitor for advanced KRAS-mutant pancreatic cancer. Phase 1 data expected H2 2026.] notreload.xyz/xy/fda-fast-...

Anthropic Secures 5GW of Amazon AI Chips in $100B Pact Amazon invests up to $25B in Anthropic for Claude AI; Anthropic spends $100B on AWS to power big AI systems.

$AMZN +2.6% [Amazon invests up to $25B in Anthropic for Claude AI; Anthropic spends $100B on AWS to power big AI systems.] notreload.xyz/anthropic-se...

BREAKING: $AAPL names Tim Cook executive chairman; John Ternus to succeed him as CEO.

Fertitta Extends Exclusive Talks to Buy Caesars in $18B Deal Billionaire Tilman Fertitta is in exclusive talks to buy Caesars Entertainment for $18B. The deal would create a large, integrated casino and restaurant empire.

Billionaire Tilman Fertitta is in exclusive talks to buy $CZR for $18B. The deal would create a large, integrated casino and restaurant empire. notreload.xyz/fertitta-ext...

BREAKING: Nasdaq snaps 13-day winning streak; Dow and S&P close lower as Iran cease-fire deadline nears.

RCUS Halts STAR-121 Phase 3 Trial & Gilead Update Arcus stops a lung cancer trial early after poor outlook, ends a partner study, and gains more control as Gilead scales back the deal.

$RCUS -5% [Arcus stops a lung cancer trial early after poor outlook, ends a partner study, and gains more control as $GILD scales back the deal.] notreload.xyz/xy/rcus-halt...

BlackBerry Shares Jump on QNX-NVIDIA AI Deal BlackBerry teams with NVIDIA to power safe AI machines, boosting stock and opening growth in robotics and healthcare.

$BB +13.3% [BlackBerry teams with $NVDA to power safe AI machines, boosting stock and opening growth in robotics and healthcare.] notreload.xyz/blackberry-s...

Morgan Stanley Keeps $80 Target on Circle After $285M Hack Morgan Stanley maintains Equal Weight rating and $80 price target on Circle despite a $285M hack on Drift Protocol using USDC.

$CRCL -2.7% [Morgan Stanley maintains Equal Weight rating and $80 price target on Circle despite a $285M hack on Drift Protocol using USDC.] notreload.xyz/circle-faces...

Cantor Initiates Coverage on CADL with $30 PT & Overweight Cantor is very bullish on CADL, sees big undervaluation and CAN-2409 as a major drug with huge growth potential.

$CADL +19% [Cantor is very bullish on CADL, sees big undervaluation and CAN-2409 as a major drug with huge growth potential.] notreload.xyz/xy/cantor-fi...

Polymarket in Talks to Raise Money at About $15 Billion Valuation The predictions site Polymarket is talking to investors about raising $400 million in funding at a valuation of about $15 billion including the new money, according to two people familiar with the tal...

Polymarket is in talks to raise $400M at a $15B valuation. This comes after NYSE owner $ICE invested $600M last month (part of a $2B deal). www.theinformation.com/articles/pol...

BREAKING: Trump says the ceasefire ends Wednesday evening and that a further extension is ‘highly unlikely.’

Rivian's factory damaged by tornado amid crucial R2 EV launch

A tornado hit $RIVN factory in Illinois over the weekend. It damaged a storage building for parts of their new R2 electric SUV (launching this spring). No one was hurt, and the main assembly lines are still running. Repairs start this week. www.cnbc.com/2026/04/20/r...

UMC Wafer Price Hike 2026: Why Chips Will Cost More UMC is charging more for chips in late 2026. Demand is too high, costs are up, and your devices may get pricier.

$UMC +8.5%, $GFS +9.2% [UMC is charging more for chips in late 2026. Demand is too high, costs are up, and your devices may get pricier.] notreload.xyz/chip-prices-...

Tesla Robotaxi Launches in Dallas & Houston – Just 1 Car Each Tesla added Robotaxi to Dallas & Houston, but there's only 1 car in each city so far. Service is very limited and hard to get. Expansion is moving slowly.

$TSLA -2% [Tesla added Robotaxi to Dallas & Houston, but there's only 1 car in each city so far. Service is very limited and hard to get. Expansion is moving slowly.] notreload.xyz/tesla-robota...

Jack Daniel’s Family Prefers French Buyer Over American Rival Jack Daniel’s owner prefers selling to French company Pernod Ricard over American rival Sazerac. They want better brands, more influence, and to keep Louisville important.

$BF.B UNCH [Jack Daniel’s owner prefers selling to French company Pernod Ricard over American rival Sazerac. They want better brands, more influence, and to keep Louisville important.] notreload.xyz/jack-daniel-...

Blue Owl to Acquire Sila Realty Trust for $2.4 Billion Sila Realty Trust is being bought by Blue Owl for $2.4B in cash, paying a 19% premium; it will go private and delist.

$SILA +19%, $OWL UNCH [Sila Realty Trust is being bought by Blue Owl for $2.4B in cash, paying a 19% premium; it will go private and delist.] notreload.xyz/blue-owl-to-...

$CADL $MP $SNSE $SERV $THO $USAR -- THE WSJ

$ACLS $BIIB $OKTA $OSCR $PLXS $WBI $PTEN $ATEN $CAR $DOCS $MHK $TVRD -- THE WSJ

BREAKING: The Dow, S&P 500, and Nasdaq open lower on Iran uncertainty, but losses are so far muted.

BREAKING: $LLY agrees to acquire cancer drugmaker Kelonia in a deal worth up to $7B.

Agios Pharma Stock Drops on Novo Sickle Cell Win Novo Nordisk’s new pill cuts sickle cell pain crises, boosting outcomes and sending Agios Pharma shares down after strong trial results.

$NVO UNCH, $AGIO -14.6% [Novo Nordisk’s new pill cuts sickle cell pain crises, boosting outcomes and sending Agios Pharma shares down after strong trial results.] notreload.xyz/xy/agios-pha...

New Drug Delivers Stronger Hair Regrowth in Severe Alopecia Areata Nektar drug showed promising hair regrowth in severe alopecia areata after 52 weeks, with good safety and twice-monthly shots.

$NKTR +17.8% [Nektar drug showed promising hair regrowth in severe alopecia areata after 52 weeks, with good safety and twice-monthly shots.] notreload.xyz/xy/new-drug-...

Passage Bio (PASG) Plunges After FDA Demands Full Trial Passage Bio fell after FDA demands bigger trial; drug shows promise for brain disease but future now costlier and slower.

$PASG -33% [Passage Bio fell after the FDA demanded a larger trial; the drug shows promise for brain disease, but its future is now costlier and slower.] notreload.xyz/xy/passage-b...

Perspective Therapeutics: 43% NET Response at AACR 2026 New alpha therapy for advanced NETs shows good safety and early tumor shrinkage in ~43% patients, with encouraging results so far.

$CATX +5.5% [New alpha therapy for advanced NETs shows good safety and early tumor shrinkage in ~43% patients, with encouraging results so far.] notreload.xyz/xy/perspecti...

Trump-Backed Mega Data Center in Crisis as CEO Quits Fermi’s huge Texas AI data center project faces delays, CEO quits, no major customer, stock drops, doubts over the massive build plan.

$FRMI -20% [Fermi’s huge Texas AI data center project faces delays, CEO quits, no major customer, stock drops, doubts over the massive build plan.] notreload.xyz/trump-backed...

USA Rare Earth Acquires Serra Verde for $2.8 Billion USA Rare Earth buys Serra Verde for $2.8B, gaining a key Brazil mine to secure rare earths supply from mine to magnets, outside China.

$USAR -5% [USA Rare Earth buys Serra Verde for $2.8B, gaining a key Brazil mine to secure rare earths supply from mine to magnets, outside China.] notreload.xyz/usa-rare-ear...

Barclays Double Downgrades Janux Therapeutics to Underweight Barclays cut Janux Therapeutics to Underweight, citing doubts on JANX007 and limited near-term upside despite long-term potential.

$JANX -3% [Barclays cut Janux Therapeutics to Underweight, citing doubts on JANX007 and limited near-term upside despite long-term potential.] notreload.xyz/xy/barclays-...

Barclays Upgrades Celldex (CLDX) to Overweight, PT $45 Barclays boosts Celldex Therapeutics on strong drug outlook; higher success odds and sales expectations.

$CLDX +2.2% [Barclays boosts Celldex Therapeutics on strong drug outlook; higher success odds and sales expectations.] notreload.xyz/xy/barclays-...

Blue Origin Puts AST SpaceMobile Satellite in Wrong Orbit AST SpaceMobile's BlueBird 7 satellite was placed in the wrong orbit by Blue Origin’s New Glenn rocket and will be de-orbited. Insurance will cover the loss.

$ASTS -11.7% [AST SpaceMobile's BlueBird 7 satellite was placed in the wrong orbit by Blue Origin’s New Glenn rocket and will be de-orbited. Insurance will cover the loss.] notreload.xyz/blue-origin-...

Eli Lilly in Talks to Buy Kelonia for $2 Billion+ Eli Lilly plans to buy Kelonia Therapeutics for $2B+. The deal would boost Lilly’s cancer business and reduce reliance on weight-loss drugs.

$LLY plans to buy Kelonia Therapeutics for $2B+. The deal would boost Lilly’s cancer business and reduce reliance on weight-loss drugs. notreload.xyz/xy/eli-lilly...