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Posts by David Tobin

Postdoctoral Position (Please re-post)
A funded postdoctoral position for a recent graduate to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology.
Please contact Hank Seifert h-seifert@northwestern.edu
#Microsky, #Microbiology, #MicrobialEvolution

6 days ago 3 11 0 0
ASM Journals Open Calls for Editors A list of current and upcoming open calls for editors at ASM Journals.

Apply to be an editor at an ASM Journal! Open call for editors at mBio, mSphere, mSystems, and Microbiology Spectrum. This is a very fulfilling way to share your expertise and give back to our society journals. @asm.org journals.asm.org/asm-call-for...

3 weeks ago 27 39 1 1

As part of the ZDMS cancer RIG 2026 meet up webinars, we want to encourage ECR participants to apply for the opportunity to share their research with our community, if you are doing cool cancer research using #zebrafish please apply here eur02.safelinks.protection.outlook.com?url=https%3A...

3 weeks ago 4 4 1 0
Picture of Zolelwa Sifumba

Picture of Zolelwa Sifumba

As today is #WorldTBDay we urge you to read this powerful interview with Dr Zolelwa Sifumba highlighting how her experience as a #tuberculosis survivor, alongside her training as a medical doctor, complements her work as a patient advocate for TBProof in South Africa

doi.org/10.1242/dmm....

3 weeks ago 3 2 0 0

Annual reminder: if you’ve been accepted to multiple graduate programs and are still deciding, please let the ones you’re definitely not going to know as soon as possible!

-Someone who got into his PhD off the waitlist the day after the deadline

1 month ago 201 82 5 3
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I’m pleased 🤗 to share our new preprint exploring the mode of action and resistance of the antitubercular drug pyrazinamide (PZA) 💊 Thanks to everyone who have participated 🙌
We hope these findings will help the fight against drug resistance in tuberculosis.
www.biorxiv.org/content/10.6...

1 month ago 32 20 4 0
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Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...

This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...

2 months ago 119 52 4 2
Albert Einstein College of Medicine | Medical Education | Biomedical Research

Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.

faculty-einstein.icims.com/jobs/17847/a...

2 months ago 27 47 1 1
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Intersections between proteostasis and immunity: insights from Caenorhabditis elegans Summary: Discoveries from the nematode C. elegans have provided insight into the many connections between immune responses and proteostasis, with examples of conservation across species.

A comprehensive and thought-provoking review on how perturbations of proteostasis impact immunity in C. elegans & comparisons/conserved principles w/ vertebrate immunity - Emily Troemel, @hawlelab.bsky.social, and Michalis Barkoulas
journals.biologists.com/dmm/article/...

2 months ago 11 5 0 0
Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

2 months ago 37 21 3 0

I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

2 months ago 28 24 1 5
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Friends! I am so happy to share our new preprint!

Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago.

How do animals like C. elegans sense it fast and escape?

www.biorxiv.org/content/10.6...

Thread 1/

2 months ago 81 31 7 3
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NC STEM Policy Post-Graduate Fellowship North Carolina Sea Grant news

Are you a recent graduate with a passion for science, technology, engineering, or mathematics — and a desire to influence public policy in North Carolina?

The NC STEM Policy Post-Graduate Fellowship is now open for applications through March 9, 2026.

ncseagrant.ncsu.edu/nc-stem-poli...

2 months ago 5 4 0 0

For scientists choosing where to build their careers, these questions are essential, and they shape who decides the U.S. is, or isn’t, a viable place to do science.

2 months ago 2 1 0 0
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Opinion | Bill Foege’s optimism helped save the world from smallpox His design of “surveillance-containment” changed the course of public health strategy.

I keep thinking about one of the last things Bill Foege said to me: “Bet on the optimists. You need the optimist to say, ‘We’re going to try to do it.’”
www.washingtonpost.com/opinions/202...

2 months ago 80 21 1 0
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2026 Microbial Toxins and Pathogenicity Conference GRC The 2026 Gordon Research Conference on Microbial Toxins and Pathogenicity will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.

Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by
@sunnyshinlab.bsky.social www.grc.org/microbial-to...

2 months ago 34 20 3 1
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Our journals @dev-journal.bsky.social, @jcellsci.bsky.social & @jexpbiol.bsky.social offer Travelling Fellowships of up to £3,000 to graduate students and post-doctoral researchers wishing to make collaborative visits to other laboratories. Apply by 6 February 2026.
biologists.com/grants/trave...

2 months ago 27 25 0 2
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Granuloma dual RNA-seq reveals composite transcriptional programs driven by neutrophils and necrosis within tuberculous granulomas Dual host-pathogen transcriptional profiling defines granuloma-specific programs during mycobacterial infection.

Excited to share work led by the wonderful Gopi Viswanathan examining roles of granuloma neutrophils &defining bacterial transcriptional profiles within mycobacterial granulomas. Cool collab with Qingyun Liu at UNC for evolutionary analysis of granuloma-specific genes www.science.org/doi/10.1126/...

2 months ago 29 8 0 2

THE NEXT INSTALLMENT OF BIOLOGY OF MYOCBACTERIA GRC WILL BE IN 2028, NOT 2027. Exact date and location TBD. Sorry about the long wait, but we think it is better long term. PLEASE repost/tell your friends!

2 months ago 7 10 0 0

Thrilled to share our new preprint showing that dietary amino acids license the NLRP3 inflammasome via mTOR-dependent mRNA translation! Congrats to co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel, co-senior author @metabailism.bsky.social & collaborators! www.biorxiv.org/content/10.6...

2 months ago 50 15 0 1

Here’s the deal with the FY26 NIH funding bill:

One line in the 1000+ pg bill = significantly less science.

The increase to ~40% of grants moving to MYF is estimated to result in a 35% decrease in the NUMBER of NIH grants funded annually—moving the paylines from 10% to around 4%.

THIS IS BAD.

2 months ago 134 89 6 4
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Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...

🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research

4 months ago 99 136 1 9
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Sharing our lab’s first publication! Probing clinical isolates of Cryptococcus, a disease-causing fungus of the lungs and brain, we found multiple heat-mobile elements that ‘jump’ in the genome at body temperature (!) with the ability to drive adaptive changes. journals.plos.org/plosgenetics...

3 months ago 30 15 1 0
ASM Mechanism Discovery Meeting - Last chance to submit your abstract. Share your science. Deadline: Jan.21, 2 p.m. ET.

ASM Mechanism Discovery Meeting - Last chance to submit your abstract. Share your science. Deadline: Jan.21, 2 p.m. ET.

Last chance to submit to the ASM Mechanism Discovery Meeting at #ASMicrobe 2026. Abstracts close Jan. 21 at 2 p.m. ET. Showcase foundational research uncovering the mechanisms that power microbial life. Submit now: asm.social/2LT

3 months ago 4 7 1 1
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Joint A*STAR - King’s College London PhD Studentships in Biomedical Science 2026/27 King's College London is seeking outstanding and motivated students to join our university and the Agency for Science, Technology and Research (A*STAR).

A*STAR/KCL PhD scholarship available!

Dream of doing cutting-edge research, travelling between continents, and becoming obsessed with modelling infections in zebrafish?

My lab and @oehlerslab.org are looking for you!

Project details: 👉 shorturl.at/mkt1a
Catalogue page 6, project 2.1!

3 months ago 2 4 0 1
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a close up of a brown surface with a few spots ALT: a close up of a brown surface with a few spots

The appropriations bill that includes NIH is being finalized.

The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants.

The House version does not and OMB has issued a veto threat if the House includes such language.

1/3

3 months ago 101 65 8 14
Opportunity Details - Faculty Opportunities

We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...

3 months ago 28 42 0 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Grinnell College has openings for two 1-year term positionsto teach microbiology and immunology. More information here:
apply.interfolio.com/179939

3 months ago 3 16 0 0
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📣Building Bridges in Leukocyte Biology #BBinLB webinar series hosted by the @leukocytebiology.bsky.social
Next speaker: @oehlerslab.org
"Differential subversion of host immune signalling by tuberculous and non-tuberculous mycobacteria"

📅 Jan 28 at 9 am EST -register free link below
#Zebrafish

3 months ago 11 5 1 2

We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!

Details below👇

3 months ago 29 42 1 0