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Posts by Felix Mikus

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Last few places left!

www.ccap.ac.uk/index.php/algaculture2026/

4 days ago 3 1 0 1
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The next of our Special Guest Presenters on CCAP’s online training course later this month is Dr Hiral Shah.
Dr Shah's talk is entitled "Exploring cytoskeletal diversity across eukaryotes using expansion microscopy"

See the link below for course details 👇

www.ccap.ac.uk/index.php/algaculture2026/

1 week ago 8 3 0 0
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Attending Protistology Open? Check out @nicolecoots.bsky.social & I's ISOP-sponsored symposium "The Symbiotic Continuum across the Tree of Life" (April 20th @ 11 AM)! We have an amazing lineup of speakers including Ondřej Pomahač, @mixotrophe.bsky.social, & Gillian Gile #ProtistsOnSky #Symbiosis

2 weeks ago 27 9 1 0
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Visualizing suborganellar lipid distribution using correlative light and electron microscopy - Nature Cell Biology Lennartz et al. introduce a correlative light and electron microscopy workflow, Lipid-CLEM, combining near-native lipid probes and on-section labelling via click chemistry. Lipid-CLEM quantitatively a...

I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you: www.nature.com/articles/s41...

4 weeks ago 139 41 8 1
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It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that:
www.nature.com/articles/s41...

4 weeks ago 183 64 8 9
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Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026

We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more

Looking for people who want to build the lab together, get in touch!

#teamtomo

1 month ago 148 47 9 11
Mobile Laboratories – A mobile, interdisciplinary facility for light microscopy, flow cytometry, and electron microscopy preparation

And the best parts about it - it's not over!
More and more data is coming out from #TREC and the science will be fantastic to engage with.
And my truck? Well it's an #EMBL facility open to the scientific community.
If you're interested have a look www.embl.org/groups/mobil... or reach out

1 month ago 8 1 1 0
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@embl.org at its best: collaborative, open, transformative, and just the right amount of crazy. Dreaming of mechanistic cell biology *in the natural environment*? Dream no more, rent the AML.

www.biorxiv.org/content/10.6...

www.youtube.com/watch?v=jepb...

#WeFreezeOnTheBeach #ProtistsOnSky 🦠🌍🧪

1 month ago 87 31 3 2
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Tissue phase transitions in development: more than just mechanics Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...

Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development!

@karengrace12.bsky.social @nicolettapetridou.bsky.social

🔗 doi.org/10.1242/dev....

2 months ago 72 26 2 2
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Researcher Florian Wollweber standing next to a cryo-focused ion beam microscope in a laboratory, with technical infrastructure visible in the background.

Researcher Florian Wollweber standing next to a cryo-focused ion beam microscope in a laboratory, with technical infrastructure visible in the background.

The origin of eukaryotic cells continues to be one of the greatest mysteries in biology.

EMBL Grenoble is excited to welcome Florian Wollweber, who will use cutting-edge imaging techniques to study Asgard archaea — microbes closely related to our earliest ancestors. 🦠🔬

www.embl.org/news/people-...

2 months ago 86 20 4 0

And @veslemoykaen.bsky.social joining from far away Lausanne

2 months ago 0 0 0 0

It was a really fun couple of weeks in the lab !
I also very much enjoyed being in full handle of the #Zeiss 3Dsim scope provided generously for us to explore the various samples.

2 months ago 19 3 0 0

This is part of our ExÂME project between @dudinlab.bsky.social @gautamdey.bsky.social Tom Richards and @moorefound.bsky.social

2 months ago 3 0 0 0

The selection of samples was incredibly diverse, both across size but also across the tree. Thanks for being a fantastic bunch! Hope it will advance your research questions!
@alfredolpsousa.bsky.social @alinaks.bsky.social @godi.bsky.social @tvasilj.bsky.social
Give them a follow if you haven’t!

2 months ago 4 1 2 0
The Dudin lab and their expansion visitors having some well deserved friday drinks and games

The Dudin lab and their expansion visitors having some well deserved friday drinks and games

A group of visitors in their lab coats busily working to get their cells and tissues expanded, stained and ready for microscopy

A group of visitors in their lab coats busily working to get their cells and tissues expanded, stained and ready for microscopy

Over the last two weeks the Dudin Lab expanded two-fold and it’s been a blast!
We are hosting a group of amazing visitors that stopped by with their own species and samples to get started with expansion microscopy.
It was a ton of fun, very much looking forward to pictures to come ❤️
#ExpandThemAll

2 months ago 30 5 1 3
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Imaging spotlight: U-ExM atlas of microbial eukaryotes - FocalPlane Imaging spotlight: U-ExM atlas of microbial eukaryotes - News

🔬🔦Our Imaging spotlight from @hiralshah.bsky.social & team highlights their U-ExM atlas of planktonic eukaryotes, including details on how you can explore this wonderful resource. Plus, check out Hiral’s top tips on getting started with expansion microscopy.
focalplane.biologists.com/2026/01/20/i...

3 months ago 22 11 0 2
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On this day in 2021, I landed in a snowy, lockdown-silenced Heidelberg to start my lab. 5 years later we are a force to reckon with in our field, and the first generation are striking out on their own. I couldn’t be more proud, & grateful to them and our wonderful collaborators around the world 🌍 🧪

3 months ago 142 9 6 0
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Another #notTHECover unfortunately.

But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.

Read here: www.cell.com/cell/fulltex...

3 months ago 100 19 4 2

We hope that integrating models with data will unlock new predictive capacity for mixotrophs--and beyond. Huge thanks to Ginger for scouting us, and to collaborators @suleles.bsky.social, @gautamdey.bsky.social, @fmikus.bsky.social, Julian Jacobs, and Kevin Archibald for building skills & ideas!

4 months ago 19 3 1 0
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We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)!

GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging.

Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations.

👉 www.unige.ch/genexm/

4 months ago 142 35 2 0

Preprint alert 🔔 Organosulfur compounds support carbon and energy metabolism in chemosynthetic symbiosis. Happy to see this cool collaboration with @organosulfur.bsky.social and others out 🥳

4 months ago 13 3 1 0

So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍

The mighty yeast reveals what we believe are general principles of centromere evolution!

Behind the curtain: communities.springernature.com/posts/counti...

#MEvoSky 🧪🌎

4 months ago 61 17 0 2
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Our attempt to give multinucleate cells the spotlight they deserve (seriously, they’re everywhere), led by the fearless @mrosjac.bsky.social and with @Markus Ganter

doi.org/10.32942/X2M...

We’d love your feedback while this goes through the peer review process!

#MicroEvoSky
#ProtistsonSky 🧪🌏

4 months ago 63 23 4 2
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How do new centromeres evolve while staying compatible with the division machinery?

Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore.

👉 doi.org/10.1038/s41586-025-09779-1

4 months ago 185 84 8 8
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So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵

4 months ago 496 165 16 32

I’m very happy that our paper is now published in Angewandte Chemie! 👏 A Photoswitchable HaloTag for Spatiotemporal Control of Fluorescence in Living Cells.
↪️ onlinelibrary.wiley.com/doi/full/10....
Big thanks again to all co-authors (especially Bego) and collaborators for their contributions! 👏

5 months ago 12 2 0 0
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New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇

www.biorxiv.org/content/10.1...

5 months ago 158 40 0 4
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PhD student in systematic biology The Department of Organismal Biology teaches and explores the evolution, development and function on the organismal level. For more information see Department of Organismal Biology - Uppsala Universit

It is a collaboration between my lab (Uppsala U) and the labs of @dudinlab.bsky.social (Geneva U) and @filiphusnik.bsky.social (OIST). More info and how to apply here:
uu.varbi.com/en/what:job/.... (The use of AI for writing the motivation letter is discouraged and will be regarded unfavourably) 2/2

5 months ago 20 9 0 1
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This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy

5 months ago 78 22 1 1
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(1/2) A new study from EMBL researchers and their collaborators provides unprecedented insights into the cellular architecture of over 200 species of plankton – tiny but ecologically critical marine organisms – using ultrastructure expansion microscopy.

Learn more: www.cell.com/cell/fulltex...

5 months ago 39 14 1 0