Happy 30th birthday to this paper published March 22, 1996, one of the studies that moved chromatin biology from correlation toward mechanism. Brownell et al. linked a transcription-associated Tetrahymena HAT to yeast Gcn5p, providing a biochemical link for chromatin modification to gene activation.

What pisses me off more than I'd like to admit is that Hegseth is too stupid/drunk/both to realize just how pathetic and weak he sounds when he thinks he's being cool and badass. It's not fair. There should be like a drug we could give him to make him self-aware and cringe until he shits himself.

as press corps, truly how are you in the same room as this man for longer than 15 mins and not get up and rock his shit???

My kids mess up one baby keem lyric they eating dry spaghetti for a week

tell it to the hague, buddy

Yesterday, five-year-old Liam and his dad Adrian were released from Dilley detention center. I picked them up last night and escorted them back to Minnesota this morning.

Liam is now home. With his hat and his backpack.

A multimodal sleep foundation model for disease prediction - Nature Medicine A deep learning-based model, developed using the rich, multimodal data available from polysomnography-derived sleep recordings, performs well on common sleep analysis tasks and predicts future disease risk across a range of diseases.

A paper published in Nature Medicine presents SleepFM: a multimodal sleep foundation model trained on over 585,000 hours of polysomnography data. It can accurately predict 130 health conditions from one night of sleep, including dementia and heart failure. 🧪🩺

I posted this in 2016 and I'll share it again.

“He was a dictator” fat nazis in plate carriers abduct your neighbors from the parking lot of target and send them to gulags.

Feels like the US has spent the last 5+ years on the verge of some kind of secular moral revival that keeps getting channeled into weirdo lifestyle puritanism

Woke 2 has arrived.

that’s fair

i get that it’s annoying to get beaten over the head with the same messaging, and listening or not listening is obviously your prerogative. but putting it all under this weird “wealth music” term and turning your nose up saying it makes you sick felt snobbish to me

i’ve seen you have this take before, specifically about rap and idk. it’s not that deep to me, to the extent where i would call someone morally bankrupt for doing it.
especially with rap, it’s dismissing the circumstances around it, and why people would want to flex their wealth a little bit

this is so impossibly pretentious holy shit

i’m getting the word that greg bovino is an actual nazi. everyone’s saying it folks!

saw wednesday live last night

they did biggie dirty with this one 😭😭

if you already didn’t have enough reasons to cancel spotify:

FUCK ICE FOREVER

Rolling Stone crowns Missy Elliott's "Get Ur Freak On" as the #1 GREATEST SONG OF THE 21ST CENTURY SO FAR 👑

"It was a nonstop freak manifesto that made the musical future sound limitless."

Ranked list: www.rollingstone.com/music/music-...

A human-specific regulatory mechanism revealed in a pre-implantation model Nature - Genetic manipulation of blastoids reveals the role of recently emerged transposable elements and genes in human development.

Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK.
Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD

ICE Nazis in Chicago tried to kidnap a food delivery worker but my man was too fast for those slow bastards

4 panel comic Panel 1: ICE “Agent” (thug) punches protester hard in the face. Agent: STOP Panel 2: ICE Agent viciously snaps protester’s arm Agent: BEING Panel 3: ICE Agent strangles protester Agent: POLITICALLY Panel 4: ICE Agent stamps on protester’s head Agent: VIOLENT

Huh wow turns out the people who wanted to misgender and deadname trans people and use racist slurs never cared about free speech, they just wanted to misgender and deadname trans people and use racist slurs

An air of sadness hangs over 9/11 this year

We Paid Some Etsy Witches to Curse Charlie Kirk If the far-right misogynist with a bad haircut wants to villainize independent women, Jezebel is more than happy to be the hag of his nightmares.

If the far-right misogynist with a bad haircut wants to villainize independent women, Jezebel is more than happy to be the hag of his nightmares.
www.jezebel.com/we-paid-some...

Charlie Kirk spent his life‘s work and all of his energy and time targeting out-groups while arguing for a world in which gun massacres would be easy to enact, plentiful, and inevitable, and he became famous and wealthy doing it, and we’re now not supposed to mention that because it’s not polite.