The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology Both Japan and the UK have recognized the growing importance of synthetic and engineering biology for transforming life science research and transitioning toward a sustainable biobased economy. Such a...

What to learn a bit about some of the topics explored at the Japan-UK Synthetic Biology Conference earlier this year? Then, check out our meeting report now out in ACS Synthetic Biology. Big thanks to all the authors and Patrick Cai and Masato Kanemaki for organising! #synbio doi.org/10.1021/acss...

A new set of mutations in the second transmembrane helix of the Cox2p-W56R substantially improves its allotopic expression in Saccharomyces cerevisiae Abstract. The dual genetic control of mitochondrial respiratory function, combined with the high mutation rate of the mitochondrial genome (mtDNA), makes m

My former colleague Kewin Gombeau explored how to improve the functional expression of a mitochondrial gene from the nuclear genome. Key seems to be reducing the hydrophobicity of certain regions of the protein to allow proper import from the cytosol. doi.org/10.1093/genetics/iyaf037

Frontiers | Genetic circuits in synthetic biology: broadening the toolbox of regulatory devices Sec. Genetic Systems and Circuit Design

I'm happy to announce that a review I co-authored has just come out: www.frontiersin.org/journals/syn...

In it, we give a comprehensive overview of regulatory devices being used in synthetic biology, look at principles employed when constructing genetic circuits, and give examples of applications.