Our H1 paper is out #ScienceAdvances:
www.science.org/doi/10.1126/...
@masaashimazoe.bsky.social et al. reveal that linker histone H1 acts as a liquid-like glue to organize chromatin in live cells. 🎉 Fantastic collab with @rcollepardo.bsky.social @janhuemar.bsky.social and others—huge thanks! 🙌 1/

How do the H2A.Z histone variant and its dedicated chromatin remodeller SRCAP regulate gene expression ?
Beautiful work from @armelletollenaere.bsky.social now published @ www.nature.com/articles/s41...

Delighted to see this published: H3K115 acetylation is associated with fragile nucleosomes at CpG island promoters and active regulatory sites. Great work from all contributors; Yatendra Kumar, @illingworth-lab.bsky.social @eliasfriman.bsky.social @helink.bsky.social

doi.org/10.7554/eLif...

Congratulations @atjanowska.bsky.social 💐🎉💯👏

#February is here! And with it, our #ImageoftheMonth:

My Mitochondrial Romance, by Pilar Padilla (Complex Metabolic Diseases and Mitochondria Lab, IRB Barcelona).

The image shows #mitochondria inside human skin fibroblasts, revealed by immunofluorescence.

Happy February everyone!

🧪🐡

Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFβ senescent secretome - Nature Aging González-Gualda, Reinius et al. demonstrate that platinum-based chemotherapy-induced senescence promotes malignancy in ovarian and lung cancer via TGFβ ligands, with evidence in mouse models validated...

New study led by Prof. Daniel Munoz-Espin in collaboration with Prof. James Brenton's and our lab 🚨🚨🚨 www.nature.com/articles/s43...