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Posts by Jenchem

📆 Reality check: “Early April” is the date to watch. The bill hasn’t been formally delivered yet. Congress is heading into recess, & there’s a procedural standoff at the White House. Once presented, the President has 10 days (Sundays excluded) to sign.

3 weeks ago 0 1 1 0
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I think about this Tony Benn speech much more than I used to

1 month ago 13254 5361 94 184

BREAKING: The Department of Education has ended its directive that attempted to restrict diversity, equity, and inclusion efforts in schools nationwide.

This is a victory for academic freedom and education equity.

2 months ago 40970 10794 475 1015

I'd argue for policies and laws that require all automotive software critical to base functions be open-sourced.

2 months ago 8 1 0 1
Person: say, i am alive.

Computer: I am alive.

Person: oh my god.

Person: say, i am alive. Computer: I am alive. Person: oh my god.

2 months ago 23392 5129 85 139
State of Rhode Island General Assembly

Today, @meghankallman.bsky.social, @mackdistrict6.bsky.social and @dawneuer.bsky.social will be among the state lawmakers from across the U.S. to gather in-person and virtually at the Minnesota Capitol for a day of solidarity with their Minnesota colleagues.

More: rilegislature.gov/pressrelease...

2 months ago 4 3 0 0
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Montana Democratic lawmakers going to Minnesota for "Day of Solidarity" A group of Democratic state lawmakers from Montana are traveling to Minnesota this week, as part of a multi-state effort to push back on what they consider the Trump administration’s “overreach.”

Montana Democratic lawmakers going to Minnesota for "Day of Solidarity"

A group of Democratic state
lawmakers from Montana are traveling to Minnesota and Minneapolis this week.

Cora Neumann, Audrey Cromwell, and Chris Pope departed Gallatin County today.
www.kpax.com/news/montana...

2 months ago 8 3 2 1

Today I saw ICE gas little white kids in the streets of Portland with chemical weapons. Imagine what they're doing to brown and black kids in the detention camps

2 months ago 29584 9804 432 288

Recall that Melissa Hortman and her husband were murdered not long ago by a fake cop who showed up at their door looking like this guy

2 months ago 32577 12283 623 275

The arrests of journalists Don Lemon and Georgia Fort are a test for every MSM member with a platform. If you are not voicing your outrage at this blatant violation of the First Amendment, you are utterly discredited as a journalist.

2 months ago 24727 7957 440 302
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U.S. Customs and Border Patrol Cmdr. Greg Bovino is seen deploying a gas canister at Mueller Park in south Minneapolis this afternoon.

Video by Ben Luhmann.

3 months ago 3798 1916 687 637

3D cell shapes come to the fore! We often focus on the apical cortex but her work reveals how complex 3D cell shapes mean that focus misses many key cell-cell contacts 🧪
www.biorxiv.org/content/10.1...

3 months ago 15 3 0 0

a heavily armed paramilitary force with legal immunity is occupying a city and going door to door kidnapping non-white adults and children in furtherance of an explicitly white nationalist political project

3 months ago 9069 3051 160 144

I guess I do think if you participated in the arrest of a five-year-old you are probably just fundamentally incompatible with society. That you are not a safe person for humanity to be around, generally

3 months ago 27684 6233 294 133
The Board recommends that NSF:

Boost participation and invite expert reviews from a wider range of industry, research institutions, venture capital, and regions of the country.
Emphasize that NSF-funded research must deliver societal benefits, including research that advances the nation's economic competitiveness and national security.
Build NSF's award portfolio at the agency level for greater nimbleness and strategic alignment with national priorities, both current and emerging.
NSF previously announced operational changes to its Merit Review to streamline, clarify, and harmonize agency funding strategies to achieve top scientific and national priorities, similar to those made by the National Institutes of Health. In the coming year, the Board will continue working with NSF leaders to implement NSB recommendations for Merit Review policy changes, such as encouraging verification of previously reported results and pursuing more bold research with high reward potential.

"We can't succeed in a new era with yesterday's playbook," says McCrary. "For our nation to win the race for the future, NSF must develop transformative partnerships with the private sector, states and communities. Together, we can blaze a trail to the next frontiers of science, usher in a Golden Age of American Innovation, and deliver on the promise of science and technology for the benefit of all Americans."

The Board recommends that NSF: Boost participation and invite expert reviews from a wider range of industry, research institutions, venture capital, and regions of the country. Emphasize that NSF-funded research must deliver societal benefits, including research that advances the nation's economic competitiveness and national security. Build NSF's award portfolio at the agency level for greater nimbleness and strategic alignment with national priorities, both current and emerging. NSF previously announced operational changes to its Merit Review to streamline, clarify, and harmonize agency funding strategies to achieve top scientific and national priorities, similar to those made by the National Institutes of Health. In the coming year, the Board will continue working with NSF leaders to implement NSB recommendations for Merit Review policy changes, such as encouraging verification of previously reported results and pursuing more bold research with high reward potential. "We can't succeed in a new era with yesterday's playbook," says McCrary. "For our nation to win the race for the future, NSF must develop transformative partnerships with the private sector, states and communities. Together, we can blaze a trail to the next frontiers of science, usher in a Golden Age of American Innovation, and deliver on the promise of science and technology for the benefit of all Americans."

The National Science Board, which oversees NSF, has published recommendations to update the foundation's merit review (which was just updated).

Below are the main points. www.nsf.gov/nsb/updates/...

4 months ago 17 17 3 15

Whoa... law is far outside my specialty, but I'm shocked that this is legal

4 months ago 1 0 1 0
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4 months ago 23369 6011 406 253
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MINNEAPOLIS: “All I did was step outside as a Somali American citizen, and I got chased by a masked person, assaulted, kidnapped. It was inhumane. If this is what’s happening to a 🇺🇸 citizen on camera, imagine what could happen to your loved ones.”

4 months ago 24753 9965 565 579
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A list of non-government database alternatives and archives We have curated a list of non-government websites with health databases. We'll continue to update this list.

The CDC has shown us that under this WH administration that they are not trustworthy

Not for vaccines
HRT
prevalence of mental health issues
& literally anything else

Look to the American Psychological Association
The American Academy of Pediatrics
& more

due diligence is more important than ever

4 months ago 14 9 1 0
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Insurance coverage of hepatitis B vaccine won’t change, industry and officials say | CNN Parents will still be able to get the hepatitis B vaccine for their children at no cost even though the US Centers for Disease and Control Prevention’s vaccine advisers recommended a major change to t...

Because the vaccine prevents chronic hepatitis B for which there is no cure and the lifelong treatment costs more than a single birth dose of the vaccine. Insurance companies recognize this is a no brainer.
Brought to you by prevention beats treatment any day.
www.cnn.com/2025/12/07/h...

4 months ago 776 309 11 14

Looks like a Stephen King character about to melt through their human skin to reveal the vile monster within.

4 months ago 61 1 2 0

wtf is a FIFA peace prize? that's like being an NFL laureate in physics

4 months ago 25626 4134 1141 313
My hand holding a shortbread cookie in the shape of an airplane. There are red sprinkles in the pattern of the survivorship bias plane.

My hand holding a shortbread cookie in the shape of an airplane. There are red sprinkles in the pattern of the survivorship bias plane.

A plate of the same cookies.

A plate of the same cookies.

Does anyone want a survivorship bias shortbread

4 months ago 15427 4178 147 107
screenshot of a post from X by the Mirriam-Webster account. Their tweet says Words step up when numbers fail. They are retweeting a post from @david_arid that reads: There was a computer flitch at the end of tonight's Nuggets game that erased all the players' stats, which led to this fantastic screengrab from the post-game show. Then there is a blurry picture from a men's basketball game and the chyron says: Time Hardaway Jr. Stats are down but he played great."

screenshot of a post from X by the Mirriam-Webster account. Their tweet says Words step up when numbers fail. They are retweeting a post from @david_arid that reads: There was a computer flitch at the end of tonight's Nuggets game that erased all the players' stats, which led to this fantastic screengrab from the post-game show. Then there is a blurry picture from a men's basketball game and the chyron says: Time Hardaway Jr. Stats are down but he played great."

I need "Stats are down but he played great" to make it into the lexicon.

5 months ago 3034 579 25 42
Cover of “233 Celsius” by Ray Bradbury

Cover of “233 Celsius” by Ray Bradbury

The first (1955) Danish edition of Ray Bradbury’s FAHRENHEIT 451. Later editions did not convert the title, so this is the only SI-compatible edition! 🎢

5 months ago 1924 492 30 48
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I love how Rep. Joe Neguse reframed this question.

5 months ago 17320 6986 711 1209
World Laureates Association announces 2025 prize winners_Latest The World Laureates Association (WLA) announced its laureates for 2025 in Shanghai on Wednesday, recognizing groundbreaking contributions in the fields of life and mathematical sciences.

warmest congratulations to Scott Emr and Wes Sundquist for being awarded the 2025 World Laureate Association Prize in life science or medicine english.shanghai.gov.cn/en-Latest-Ta...
WLA doesnt do a great job advertizing in the US so i am doing their job for them. So well deserved!

5 months ago 21 9 0 0

Whenever people complain about the number of folks relying on food stamps, it is worth reminding them that SNAP is, by too large of a degree, a subsidy for corporations that refuse to pay a living wage and their political allies who reject public policy prescriptions to reduce income inequality.

5 months ago 34607 11394 851 675
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Mechanism of single-strand annealing from native mass spectrometry and cryo-EM structures of RAD52 homolog Mgm101 RAD52, the primary single-strand annealing (SSA) protein in humans, forms undecameric rings that bind ssDNA within a narrow, positively-charged groove. Whether RAD52 anneals two complementary ssDNAs on the same ring in cis, or between two ring- ssDNA complexes in trans, is unknown. Here, we determined cryo-EM structures of Mgm101, a RAD52 homolog from yeast mitochondria, in complexes with ssDNA, a duplex intermediate of annealing, and B-form dsDNA product. In all states, Mgm101 forms a closed nonadecameric ring that binds the backbone of the first ssDNA at the base of the narrow groove. The second complementary strand binds directly on top of the first to form an extended, unwound, and circular duplex intermediate of annealing. A third complex captures apparent B-form DNA product bound to a novel beta-hairpin motif located on top of the Mgm101 ring, above the primary DNA-binding groove. Mass photometry and native mass spectrometry confirm and further elucidate the complexes formed in solution. Altogether, our data reveal the full SSA pathway of Mgm101 and suggest it anneals two complementary ssDNAs on the same ring in cis. Structural conservation with RAD52 suggests it is likely to use a similar cis mechanism of annealing.

(BioRxiv All) Mechanism of single-strand annealing from native mass spectrometry and cryo-EM structures of RAD52 homolog Mgm101: RAD52, the primary single-strand annealing (SSA) protein in humans, forms undecameric rings that bind ssDNA within a narrow, positively-charged… #BioRxiv #MassSpecRSS

5 months ago 1 1 0 0