Does GLUT4 Queue? A Mechanistic Mathematical Model for Insulin Response in Adipocytes - Bulletin of Mathematical Biology Mammalian cells regulate their glucose levels by redistributing glucose transporter proteins within the cell. Glucose Transporter 4 (GLUT4) is the main insulin-regulated glucose transporter in mammali...

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We develop a queueing model of intracellular GLUT4 translocation. Fitting the model to data allows us to uncover a possible mechanism of GLUT4 sequestration and release in response to insulin.

link.springer.com/article/10.1...

Nice best paper talk on methods for fitting time series data to stochastic models by Brock Sherlock at UNSW. Paper 👉 doi.org/10.1007/s115.... @smbmathbiology.bsky.social at #Anziam2025 MBSIG workshop.