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Posts by Arthritis Research Canada

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Our team is comprised of scientists from across Canada 🇨🇦, spanning multiple disciplines.

Pictured here: our rare disease registry team meeting in Halifax. It was such a valuable opportunity to connect in person. Moments like this remind us how powerful national collaboration is!

3 days ago 20 2 2 1
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Pregnant patients with rheumatic diseases face higher preeclampsia risk. In our study from a Canadian registry, most met criteria for low-dose aspirin (ASA). While outcomes were similar between groups, findings support low-dose aspirin use in high-risk patients per guidelines. #Rheumatology #OBGYN

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- 1 in 4 people who experienced sleep disturbances used cannabis to improve sleep/arthritis symptoms & many felt it provided some relief.

- Cannabis users did not report better health-related QOL or better arthritis symptoms, & reported significantly worse anxiety & depression than non-users.

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PhD student Nicole Andersen & scientist Dr. Deborah Da Costa presenting their study that looked at cannabis use in people with inflammatory arthritis enrolled in testing an intervention for insomnia.

🔑Key findings in ⬇️ reply.

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CRA Annual Scientific Meeting 2026 - Day 1: April 17 - Arthritis Research Canada Learn about the arthritis research our scientists are presenting at the 2026 CRA & AHPA Annual Scientific Meeting.

Dr. Choi & team identified a promising new biomarker of lung disease in people with inflammatory diseases of the muscles. This blood test could allow earlier detection, and treatment, of deadly lung complications of this disease. Presented by Nathan Barreth at CRA.
🖇️To learn more: ow.ly/9ckM50YKJiJ

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Pictured here is Arthritis Research Canada scientist Dr. May Choi and her team at the 2026 CRA Annual Scientific Meeting!

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Some highlights from our team include testing of programs: 1. an online program for insomnia, which was successful at improving sleep scores for people with arthritis & 2. an 'Appointments by Choice' system which provides a new way of providing flexible follow up care for rheumatoid arthritis.

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CRA Annual Scientific Meeting 2026 - Day 1: April 17 - Arthritis Research Canada Learn about the arthritis research our scientists are presenting at the 2026 CRA & AHPA Annual Scientific Meeting.

We are excited to share executive summaries of the research abstracts that Arthritis Research Canada scientists & trainees are presenting at the 2026 Canadian Rheumatology Association Scientific Meeting. Check out our presentations here: ow.ly/9ckM50YKJiJ

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Congratulations to Dr. Raheem Kherani for being recognized with a Practice Reflection Award from the Canadian Rheumatology Association for leading the development of a mini practice audit tool with UBC rheumatology resident Dr. Madelaine Beckett that allows rheumatologists to review & improve care!

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On behalf of our team at Arthritis Research Canada, we want to congratulate Dr. Barnabe on this well-deserved achievement! 🎉

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Our Scientific Director Dr. @dlacaille.bsky.social & scientist Dr. Cheryl Barnabe are at the 2026 CRA Annual Scientific Meeting in Halifax this week.

Dr. Cheryl Barnabe was honoured with a Distinguished Investigator award for her research & work providing arthritis care in Indigenous communities.

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🚨 The bottom line is... Use HCQ ≤5 mg/kg/day. Screen with SD-OCT within 1 year, then annually from year 5 (earlier for >5 mg/kg/day, CKD, female, Asian patients).  
🔗Link to publication: acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
@aavina.bsky.social

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Our new study finds HCQ retinopathy risk increases with duration and dose. Pooled prevalence is 5.1%, and cumulative incidence reaches 5.6% by 15 years. Higher risk: >5 mg/kg/day, CKD, female sex, Asian ethnicity. This supports dose optimization and targeted SD-OCT screening.

3 weeks ago 2 0 1 0
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Pregnancy Outcomes of Targeted Synthetic Disease-Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review - PubMed Our scoping review of evidence to date on the perinatal use of tsDMARDs reveal small sample sizes and a limited number of studies, all largely descriptive in nature. Findings highlight evidence gaps that preclude providers and patients from making informed decisions when considering the perinatal us …

Reported outcomes: congenital anomalies, preterm birth, spontaneous abortion, but data were limited.
⚠️ Major evidence gaps remain that preclude providers and patients from making informed decisions when considering the perinatal use of tsDMARDs.
🔗 Link to paper: pubmed.ncbi.nlm.nih.gov/39895048/

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🧪📚 Our team's scoping review of tsDMARD use in pregnancy: From 6,712 records, only 8 studies met criteria (mostly case reports; n=1–116). Evidence was available on tofacitinib, baricitinib & upadacitinib; none on apremilast.

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Prognosis and long term outcome of stenotic large vessel involvement in giant cell arteritis. Graphical abstract created using BioRender

Prognosis and long term outcome of stenotic large vessel involvement in giant cell arteritis. Graphical abstract created using BioRender

Stenotic large vessel vasculitis is a rare and largely unknown subtype of giant cell arteritis (GCA). Retrospective study of 3,149 patients evaluated long-term outcome and prognosis of GCA with stenotic LVV

Arthritis & Rheumatology
acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

1 month ago 3 2 0 0
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Spondyloarthritis preceding and following inflammatory bowel disease diagnosis and risk factors: a temporal trends analysis in a population-based cohort. A graphical abstract

Spondyloarthritis preceding and following inflammatory bowel disease diagnosis and risk factors: a temporal trends analysis in a population-based cohort. A graphical abstract

In a nationwide cohort, spondyloarthritis diagnosis was associated with inflammatory bowel disease preceding & following its diagnosis. Findings also demonstrated temporal variability & highlighted clinical variables associated with SpA in IBD

A&R
doi.org/10.1002/art....
@predictibd.bsky.social

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Randomised controlled trial led by @lli-1.bsky.social shows counselling combined with self-monitoring tools can help people with #RheumatoidArthritis manage their condition better. It can also improve symptoms like fatigue & mood.

🔗Link to paper: pubmed.ncbi.nlm.nih.gov/38152927/

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Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation-associated protein 5 (anti...

Bottom line: ILD may progress despite myositis remission. Ongoing pulmonary monitoring is essential 🫁

Link to paper: acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

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ILD trajectories differ across IIM subsets. In a BC cohort (n=111), our team found that PmPPF occurred in 13.5%, mainly in anti-MDA5+ DM & antisynthetase syndrome, and was absent in scleromyositis. PmPPF associated with ↑ active disease, ↑ rapidly progressive ILD & ↑ transplant (20% vs 1.3%).

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Published in Arthritis & Rheumatology @acr-journals.bsky.social : acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

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New population-based study (n=229,300 T2D): GLP-1RAs & SGLT2is showed no ↑ or ↓ in overall autoimmune rheumatic disease risk vs. DPP4is. But SGLT2is were linked to ~50% ↓ risk of systemic ARDs. Study led by Dr. @derinkaracabeyli.bsky.social. See infographic 👇

2 months ago 2 0 1 0
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Arthritis At Home 306 – A discussion on rheum-oncology and artificial intelligence in rheumatology | Arthritis At Home This episode of Arthritis At Home features Dr. Carrie Ye, an Associate Professor in the Department of Medicine at the University of Alberta.

JointHealth™ express - #ArthritisAtHome 306 – A discussion on rheum-oncology & artificial intelligence in rheumatology.

Watch now: arthritisathome.jointhealth.org?p=6743

#cancer #arthritis #AI @arthritispower.bsky.social @arthritistrainees.bsky.social @schroeder-uhn.bsky.social @achronicvoice.com

3 months ago 4 3 0 0
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Takin hydroxychloroquine as prescribed- reduces hospitalizations snd save dollars!! - as simple as that!!

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Glucagon-Like Peptide-1 Receptor Agonists, Sodium-Glucose Cotransporter-2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases. Graphical abstract created using BioRender

Glucagon-Like Peptide-1 Receptor Agonists, Sodium-Glucose Cotransporter-2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases. Graphical abstract created using BioRender

What is the impact of GLP-1RA & SGLT2i use on risk of developing autoimmune rheumatic diseases (ARD)? Data from a Canadian cohort of adults w/ type 2 diabetes showed SGLT2i use was assoc w/ lower risk of systemic ARDs, but neither GLP-1RA nor SGLT2i treatment was assoc w/ lower non-systemic ARD risk

3 months ago 2 2 1 0

🔗Link to full paper: acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

2 months ago 0 0 0 0
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Our new study finds that early antimalarial adherence (PDC≥0.90) in incident RA/SLE is associated with lower acute care use & costs (BC cohort, 1997–2022; n=25,247): 11% ↓ admissions (RR 0.89), 21% ↓ hosp days (RR 0.79), −$550 CAD costs. Robust to sensitivity analyses. See graphical abstract below.

2 months ago 0 0 1 1
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JointHealth™ express - Now Launching: JointHealth™ Education – #Arthritis and #MentalHealth. Click here to begin the course: bit.ly/JointHealthE...

Thank you Dr. Susan Bartlett for your help with this course! 🥰

@schroeder-uhn.bsky.social @arthritistrainees.bsky.social @arthritispower.bsky.social

2 months ago 2 3 1 0

Creation of these guidelines was led by the Canadian Rheumatology Association (CRA) and the Canadian Research Group of Rheumatology in Immuno-Oncology (CanRIO), with collaboration from several Arthritis Research Canada scientists.
📄 Paper 1: shorturl.at/7UPGf
📄 Paper 2: shorturl.at/PP718

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New Canadian living guidelines address an important gap in cancer care: managing immune checkpoint inhibitors in patients with pre-existing inflammatory arthritis & systemic autoimmune rheumatic diseases. See GRADE-based, disease-specific recommendations in the embedded infographic.

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