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Posts by ShanYanLab

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We are excited to invite you to the inaugural 2026 Southeastern Symposium on Genome Integrity and Chromatin Regulation, to be held at UNC Charlotte on June 15, 2026.
Details: biology.charlotte.edu/ssgicr/

2 months ago 0 0 0 0
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Trilled and humbled to received the 2025 Outstanding Faculty Research Award by Department of Biological Sciences at UNC Charlotte. Thankful to my mentors, collaborators, current/former lab members, friends and family. @emgsus.bsky.social @asbmb.bsky.social

4 months ago 4 1 0 0

Congratulations

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Congratulations

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Congratulations

5 months ago 1 0 0 0
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Among the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social

www.science.org/doi/10.1126/...

5 months ago 53 22 6 1
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Human RPA is an essential telomerase processivity factor for maintaining telomeres Telomerase counteracts telomere shortening by repeatedly adding DNA repeats to chromosome ends. We identified the replication protein A (RPA) heterotrimer as a telomerase processivity factor critical ...

Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...

5 months ago 124 41 10 5
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Our #EMGS2025 Sam Wilson Award Lecturer, Mark Hedglin is presenting a wonderful talk in Platform 1: DNA Repair, "Rad6 Is Dynamically Accessible for Activation Within the Rad6(Rad18)2 Complex: Mechanistic Insights into a Ubiquitin Cascade Critical for Human DNA Damage Tolerance"!

7 months ago 3 1 0 0
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Our #EMGS2025 Hollaender Award Lecturer, Dr. Carole Yauk is speaking now!

Attendees: Don’t say you would’ve, could’ve, should’ve been there, and go see her talk, “The Eras Tour: A Genomic Journey Through the Evolution of Applied Genetic Toxicology.”

7 months ago 2 1 0 0
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Our #EMGS2025 EMGS Award Lecturer, Dr. Dana Dolinoy, is starting off day four of #EMGS2025 with a fantastic talk on "Toxicoepigenetics and the Use of piRNA for Precision Environmental Health Research"!

7 months ago 3 1 0 0
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2025 EMGS annual meeting

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