mcp-ui demo showing a description of the aim of the demo
Finally I can properly explore the mcp-ui pattern. Pretty interesting how the development of new components (especially complex ones) will change dramatically in how data is loaded into them. Exiting times🔥 building a demo using @opentargets.org components.
Ref: mcpui.dev
Open Targets Platform 25.12 is out now!
Thanks to a GWAS Catalog update including 3 major studies using UK Biobank data, we now have over 1.4 million GWAS credible sets in the Platform.
Discover the data, feature, and technical updates in this release: blog.opentargets.org/open-targets... 🧬🖥️
Totally agree
A large group of people sat on steps in a building, smiling at the camera. The front row is holding bunting with the Open Targets logo.
And that's the Open Targets Hackathon done! 🧬🖥️
Thank you to everyone who joined in person and online, and who contributed to make this event a success
Particular thanks to our sponsors: Gates Foundation, Google Cloud, and @thehyvenl.bsky.social 🎉
CLOSING: Front end developer for the Open Targets Platform
Join @carcruz.dev's team and help us turn complex data into powerful discovery tools, working closely with our industry and academic partners
Apply by 19 August
embl.wd103.myworkdayjobs.com/EMBL/job/Hin...
#ReactJobs #DevJobs
Text reads: Open Targets hackathon, 21-22 October 2025, compute sponsored by Google Cloud
Google Cloud is sponsoring the compute for the Open Targets hackathon!
There is now a waiting list to attend the event in person, but project submissions and online registrations are still open.
The two-day hackathon will explore data, analyses, and tools for target discovery
Carlos Cruz smiles at the camera from a bridge over a small river in a European town on a cloudy day.
Meet Carlos Cruz! Carlos joined the Open Targets Platform team in 2021 🖥️🧬
@carcruz.dev, what is your role in Open Targets?
I’m also really into software, beyond just front-end. I like reading about new architectures, clever implementations, and how people build and ship products.
If you’re into dev tools and design systems or just need someone to debate whether HTML+CSS is a programming language, I’m in!
Photo of the cat, the plants, and the football. Alt: Laid out on dry grass in a garden are an array of house plants in pots, waiting to be repotted, and, a cat with its back to the camera, and a football.
Pretty much anything! I’m really into gardening and play football regularly to stay active.
👇My neighbour’s cat Heathcliff sometimes comes to hang out with me while I’m gardening.
You have to anticipate how technical decisions will ripple through the entire product ecosystem.
It’s not just about writing good code or building nice UIs, it’s about understanding how architecture choices affect user experience, team delivery, and product scalability down the line.
photo of the AOTF and Target Prioritisation views. Alt text: Screenshots of the Associations on the Fly and Target Prioritisation views in the Open Targets Platform.
Our UI development environment (ot-ui-apps).
It’s been the foundation for numerous new features, such as Associations on the Fly or the quick development of genetics-related page widgets. It has streamlined our development process, improved code consistency, and enabled better project collaboration
It’s been amazing to experience a different culture and gain a new perspective on work-life balance.
And for sure, fruits are not the same!
Moving from Costa Rica was quite an adjustment. Going from consistent tropical weather to seasonal cycles meant I had to adapt my daily routines; it was a lot of effort.
There is something rewarding about knowing that the code and data we develop can be used, improved, and accessed by researchers globally.
I want to build tools that combine software and product engineering with meaningful scientific impact.
And it’s amazing to see how the Open Targets Platform contributes to biological research.
I’m the Lead Front-End Engineer at Open Targets, where I develop and maintain the Open Targets Platform, making genomic and therapeutic data accessible to researchers.
Glad they were open for a conversation/debate. As costarican living in UK, this is a constant situation I have lived
Cooking 🧑🍳
Significant upcoming updates to the ot-ui-apps repo!
Meme: Jeremy Clarkson and Richard Hammond comparing two cars. In the first image, Jeremy points to one labelled "Open Targets Genetics" saying, This is brilliant. In the second image, he points to another labelled "Merged Open Targets Platform" saying, "But I like this".
We have now deprecated Open Targets Genetics — it has been superseded by the Open Targets Platform
The team said goodbye to Open Targets Genetics, through the medium of memes
Enjoy!
Osteoporosis associations page on the Open Targets Platform showing GWAS associations evidence for ESR1
🧬 The latest Open Targets Platform release includes the first genetic evidence for ESR1 in osteoporosis
ESR1 is a known target for osteoporosis, with approved drugs such as Estradiol, but this is the first time we have genetic evidence for this association
platform.opentargets.org/disease/EFO_...
Open Targets Platform 25.06 is out now! 🌻
It includes 36% more GWAS credible sets (including from the VA Million Veteran Program study) and a new target interactors view to help nominate potential targets
blog.opentargets.org/open-targets...
This was my flight home. No internet, no AI. Just me and my vim motions.
"but sir, why would you code without AI?"
...why do people solve sodoku puzzles? There's no "reason" really. It's just fun to use your brain sometimes
Really nice to finally see, imo, a proper readable/reusable way to implement RSC gradually
Found some amazing work in this dataviz portfolio from Liuhuaying Yang et al. for @csh.ac.at
csh.ac.at/visuals/
Text reads: Announcement, Open Targets Genetics will be deprecated on 9 July 2025
Open Targets Genetics will be deprecated on 9 July 2025
You will no longer be able to access genetics.opentargets.org. An archive of the data will be accessible through the EMBL-EBI FTP
We are happy to help with questions or concerns on the Open Targets Community: community.opentargets.org
Excited to share our "Associations on the Fly" paper in Oxford Bioinformatics! 🧬🔍
In @opentargets.org we built this tool to visualise multi-level data on a single screen, helping researchers navigate complex evidence without switching context.
Check it out: academic.oup.com/bioinformati...
Out now in Bioinformatics! @carcruz.dev and Annalisa Buniello present our new interactions view: Associations on the Fly
"Our primary goal in creating AOTF was to build a tool that could represent multiple levels of analysis on the same screen."
academic.oup.com/bioinformati...
Big thanks to the community for the great feedback we are receiving on the spring @opentargets.org Platform release. There are many positive and new ideas for improving our scientific interpretation and products. Feedback is a critical aspect of an open project's lifecycle. Please keep it coming 🧬🖥️
