Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

Research Organisms in Flight: Revealing the Roots of Vertebrate Form… Organized by Tatjana Sauka-Spengler, Ph.D., and Ruth Williams, Ph.D.

One week left for early-'bird' (pun intended) registration...Join us @stowersinstitute.bsky.social @saukaspengler.bsky.social this fall for all the bird talk!! www.stowers.org/events/avian...

Transcriptomics and chromatin accessibility signatures define the cervical-thoracic boundary along the vertebrate axis In vertebrate embryos, somite pairs form on either side of the neural tube along the main body axis. Somites generate the tissues of the musculoskelet…

New paper from the Munsterberg lab!
Shannons PhD project is finally out, showing off her hard work on how the cervical-to-thoracic boundary is established during development. She combined ATAC- & RNA-seq to identify key regulatory elements of HOXC6 and HOXC8.

www.sciencedirect.com/science/arti...

Growing Up: Development over a Lifetime How does a single egg become a human, and how does this shape our aging? From the earliest heartbeat in embryos to the aging of blood vessels, we’ll explor…

Excited to be speaking at this year’s Pint of Science in Norwich! I’ll be joining two other female scientist to talk all about development over a lifetime. Looking forward to a great evening of science! #pint25
pintofscience.co.uk/event/growin...

🚨Registration for the UK #EvoDevo meeting is open! Join us on July 11th in London to enjoy an exciting day of talks, posters, friends, and superb science!
-Registration (only £5!): shorturl.at/9cQGL
-More info: londonevodevo.ac.uk

β-catenin-driven endomesoderm specification is a Bilateria-specific novelty - Nature Communications Lebedeva et al. show that unlike Bilateria, the embryo of the cnidarian Nematostella specifies its endomesoderm in the β-catenin-negative domain. In contrast, subsequent β-catenin-dependent axial patt...

Tanya's @tclebedeva.bsky.social paper on endomesoderm specification in the beta-catenin-negative area of the Nematostella embryo is out! www.nature.com/articles/s41...

A still image of a stage HH4 gastrulating chick embryo electroporated with 3 different fluorescent reporter genes shown in magenta, yellow and cyan.

Need to electroporate and/or live image avian embryos? We hope our new preprint will help you get started:

www.biorxiv.org/content/10.1...

Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo

🧪🐣 #devbio

Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

Our latest: uncovering hierarchical design rules for cis-regulatory elements with a high-throughput screen

CRE activity follows multiplicative modular rules, tuned by spacing & positioning

Enables engineering synthetic CREs for predictable tissue patterning

www.biorxiv.org/content/10.1...

Please come along to tomorrow's Slice of Science! We will be hearing talks from Lucio Sousa Pinheiro in MED and Magdalena Schatka in BIO, as well as hearing some exciting announcements for PGRs!

A whole-body atlas of BMP signaling activity in an adult sea anemone - BMC Biology Background BMP signaling is responsible for the second body axis patterning in Bilateria and in the bilaterally symmetric members of the bilaterian sister clade Cnidaria—corals and sea anemones. Howev...

Our atlas of BMP signaling activity in adult Nematostella is finally out! Fantastic, meticulous work and beautiful illustrations by @paulknabl.bsky.social
Thanks, @fwf-at.bsky.social for funding our work!
bmcbiol.biomedcentral.com/articles/10....