I was truly heartbroken to hear about Richard's passing.
He was a great mentor and the one who introduced me to the amazing world of proteins. Richard would see the beauty in science, and science in daily life objects, and his vision really shaped my own approach of biomolecular modeling.
Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization
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Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization [new]
Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization www.biorxiv.org/content/10.64898/2026.04...
Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization www.biorxiv.org/content/10.64898/2026.04...
Elections législatives en Hongrie : le Premier ministre sortant Viktor Orban reconnaît sa défaite face au leader de centre droit Péter Magyar www.franceinfo.fr/monde/europe...
🚀 The af_analysis GUI is out!
Load datasets, compute advanced scores (ipSAE, LIS, pDockQ2…), cluster models, and explore PAE matrices + Mol* interactively.
Install with:
pip install af_analysis[gui]
github.com/samuelmurail...
📣 Two weeks left to apply! 📣
I2BC is recruiting new team leaders in molecular and cellular biology, with special attention to multidisciplinary approaches and computational biology. 🧬🧪🔬👩🔬🧑💻
We provide a great environment with top-notch technological facilities.
🗓️ Apply by April 22, 2026!
Two (or more) PhD student positions are open with me in protein structure evolution (using AI). Please apply/spread the word.
su.varbi.com/en/what:job/...
Attention Military Servicemembers
If you’re in the US military and seeking discharge or reassignment as a Conscientious Objector, we can help. We’ll work with you to navigate the complex admin process. Services are free of charge. If you’re facing deployment, don’t wait to call us at 800-379-2679.
The Critical Assessment of Structure Prediction (CASP) experiment is calling for prediction targets: Immune Complexes, Organic Ligand-Protein Complexes, Nucleic Acids and Complexes, Conformational Ensembles, Difficult Protein Structures and Complexes. Rule of Thumb: If AlphaFold3 can generate a high-quality model, it is likely not a CASP-grade challenge. If it struggles, we want it.
Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬
Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes.
The Rule of Thumb: If AF3 can’t model it, we want it.
Fil RH #CNRS de la semaine
#ESR #SNPTES #VeilleESR
Des nouvelles du baromètre social au CNRS ?
Je grille la politesse à la DRH qui a prévu prochainement une communication sur les résultats du barom social lancé en janv ; et bah, en voici qqs éléments, en exclusivité mondiale ! (pas du tout)
1/14
New preprint🚨
Imagine (re)designing a protein via inverse folding. AF2 predicts the designed sequence to a structure with pLDDT 94 & you get 1.8 Å RMSD to the input. Perfect design?
What if I told u that the structure has 4 solvent-exposed Trp and 3 Pro where a Gly should be?
Why to be wary🧵👇
La science n'est pas toujours d'accord avec notre intuition. C'est pour ça qu'on fait de la science : pour ne pas seulement suivre le bon sens (celui qui peut nous faire croire que le soleil tourne autour de la Terre).
À la maison on est passé de 2/4 à 4/4 après 18h. Mais on ne vote pas à Paris...
Il fait beau les gens vont voter en rentrant de leur sortie ...
Non pas vu... Dommage...
You asked, we listened. Millions of AI-predicted protein complex structures are now available in the #AlphaFold Database.
This spans homodimers from 20 of the most studied species, including humans, as well as the World Health Organization’s priority pathogens list.
www.ebi.ac.uk/about/news/t...
"AI" is not a stochastic parrot.🦜
I wrote this piece a couple weeks ago, but it was hard for me to finish up given AI's role in society and war over the past few weeks. I should share it at some point though. Not perfect, but here it is.
medium.com/@margarmitch...
holy shit
Original (left) and corrected (right) Fig. 4a in the paper https://www.nature.com/articles/s41586-026-10305-0 showing the chemical structures of amino acids (only the right one) the left figure is just an embarrassment
I wonder... 🤔🤔🧪 #chemsky
a) what program did the authors use to make the original (left) figure in the paper? Wild guess, ChatGPT
b) how such high school science level of disgrace pass peer review in @nature.com?
Note this was Fig.4.a NOT in SI
www.nature.com/articles/s41...
We are currently recruiting PhD students, postdocs, and a group leader to join the Institute.
If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: johannes.rebelein@hhu.de.
We could be interested to articulate your genome wide approach results with our tests targeting specific membrane proteins.
The IBS in Grenoble has an opening for a three-year postdoctoral researcher in SNaX team of the DYNAMOP group. The aim of the researcher is to advance data analysis tools for time-resolved serial X-ray crystallography and cryo-EM.
For more information, see instruct-eric.org/jobs/postdoc...
We;re hiring Junior Group Leaders! 🔬✨
We’re looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment.
www.nki.nl/news-events/...
Des scientifiques découvrent que la violence aurait été inventée avant les jeux vidéos www.legorafi.fr/2026/02/20/des-scientifi...
Logo MERIT SFBI
📌 Enquête MERIT-SFBI sur les conditions de travail des bioinformaticien·ne·s dans les instituts de recherche, universités, établissements d’enseignement et recherche, secteur associatif ou privé
📎 framaforms.org/enquete-meri...
⏳ temps estimé : 20 minutes
📅 date limite de réponse : 31/03/2026
As far as I understand it the current problem with the winter Olympics is that it is snowing...
C'est le principe de la roulette russe... Et c'est général les mauvaises nouvelles s'accumulent dans ma boîte mail ...
Désolé que vous subissiez la loterie. Bon courage !
Graphic showing changes in CO₂, global temperatures and global sea levels over the last 2025 years. Steep increases are visible after the industrial revolution.
Updated climate indicators graphics, now including 2025
ed-hawkins.github.io/climate-visu...
