New blog post!
I use ntHash all the time to hash k-mers, yet it turns out it has some unexpected flaws (collision propagation, bias on leading zeros...). The good news: each of them can be fixed!
igor.martayan.org/posts/breaki...
A photo of a large barn flanked by rolling green hills on a bright spring morning.
A photo of a seated crowd in the barn, as Adrianna Tan is on stage presenting. The slide currently projected on screen reads: Do not want - Work on ads - Work on weapons - Abet genocides - Make the world worse - Use Microsoft Teams
A photo of a glorious orange cat cleaning themselves in a barn window.
A photo of a crowd of folks who stuck around at the end of North Bay Python 2025 to help clean up.
@northbaypython.org returns for its 7th year this Apr 25 & 26! Join us for a tech conference like no other, featuring barn cats, about the tech we build and the people we build it for.
We're a small local event with a global draw. If you've never been, come find out why 😁
northbaypython.org #NBPy
ganhei um leitor novo pelo Lerama do @manualdousuario.net , fui fuçar e achei outros posts mto legais pra conhecer outros blogs e newsletters
Já fiz meu apoio pra CryptoRave deste ano e seria muito importante mais gente ajudar nessa reta final também (faltam só 4 dias pra bater a meta de financiamento coletivo🙏🏼)
www.catarse.me/cryptorave2026
The current moment in tech is loosely understood as software guys getting so evil they made hardware guys discover Marxism from first principles.
I find it super frustrating, we were that close to modularity with Rust, and you port nice librairies with fine APIs to C? I'm judging you. 👀 If you wish to vibe code then Claude can interface the Rust for you instead?
Our work on 'hidden diversity' in unbinned contigs is now published in @natmicrobiol.nature.com :
www.nature.com/articles/s41...
See the linked threads for more details!
Thread de utilidade pública.
É o tipo de discussão que deveria ser feita pela imprensa, se ainda existisse jornalismo no Brasil. Infelizmente o jornalismo de tecnologia hoje serve de relações públicas pra Big Tech.
Saiu na piauí a carta aberta que escrevi ao menino que teve a redação zerada na Fuvest. Conto um pouco da minha experiência antiga e deixo dicas para a próxima vez em que ele for tentar. Espero que as dicas sejam úteis a mais gente.
A quick rant on people vibe-translating our Rust libraries to other languages
That's the second time in a week that I see new bioinformatics tools with a vibe-coded translation of our Rust libraries to C/C++.
I have two major issues with that:
photograph or a poster on cream colored paper. "Dear President Ambar, we are writing to you on a typewriter that is over 70 years old. This is a machine that we all know well. With it, we misspell words without the crutch of spell check or generative AI and we think intently about every phrase we pound out. As we force ourselves, for once, to slow down, we engage in a cognitive dialogue with ourselves. We do not seek perfection because we know that education is about the growing and challenging of our young minds' potential, not the chasing of institutional 'gold-star' approval. We do not believe that your so-called 'Year of AI Exploration; providing enterprise ChatGPT and Google Gemini subscriptions to every Oberlin student aligns with our college's founding principles. You claim that this year will be one of experimentation, not adoption. But even just one semester of accepted (encouraged even) chat bot use will jettison our student body down a lazy and irredeemable tunnel of intellectual destruction. We are a college grounded in learning and labor, which now risks straying from these rooted ideals. With ChatGPT at the helm, our emails, essays,and discussion posts will be generated for us, not by us. And let's not fool ourselves. This is precisely what these platforms will be used for by our busy, anxious student body. We see your vision for this year as.advancing the college's 'businessification'--an alarming trend also seen in the takeover of our beloved library cafe by a 'bookstore' with no books in stock and an app replacing customer service. In one instance, the college assumes we want efficiency at all costs through automated rather than hand pulled coffee. In the other lies the false belief that we simply desire to turn in an essay, regardless of how little we've written of it." there's more that doesn't fit in the 2000 character limit :(
OH MY HEART...the Oberlin Luddites Reject "The Year of AI Exploration"! 💚
Why phylogenies compress so well: combinatorial guarantees under the Infinite Sites Model www.biorxiv.org/content/10.64898/2026.03...
GG Lasso
um traço geracional forte é que mesmo com outras telas, uma pesquisa séria me faz abrir o notebook, não tem jeito
Preprint alert!
TLDR:
Super Bloom is a Bloom-filter variant for streaming k-mer queries.
It uses minimizers to group adjacent k-mers into super-k-mers and map them to the same memory block.
Result: much better locality, faster queries, and with the findere trick, dramatically fewer false positives.
We have two paid internships available in our group starting this summer, suitable for master's / pre-PhD students:
- Protein structure search
- Promoter variation
For full details and how to apply see: www.bacpop.org/jobs/
We're Hiring! Computational Biologist / Genomic Data Scientist.
Join our lab to use cutting-edge data & AI/ML to advance human health.
- Genetics & Genomics analysis
- AI/ML in biology
- Solving real-world genomic problems
📄 Full details: docs.google.com/document/d/1...
Preciosidade absoluta: tem até show dos Cascavellettes em Viamão em 1991.
Harry Potter tattoo regret rate is an order of magnitude higher than regret for Gender Reassignment Surgery and yet no one has been brave enough to suggest we legislate Harry Potter tattoos.
Terramar é bom demais, e a partir de Tehanu vai pra um caminho que deixa melhor ainda
As três melhores conferências técnicas do Brasil são a #PythonBrasil, a #Gambiconf, e a #Tosconf.
Sábado tem #Tosconf, e vou apresentar meu tutorial sobre construção de interpretador em 120 minutos.
Olha que maravilha a programação, pessoal!
tosconf.lhc.net.br
Prezados, no ano passado eu praticamente desisti de tentar lecionar em turmas regulares. Há tempos venho pensando em oferecer cursos livres meus, e agora estou na fase final disso. Queria entender um pouco mais o que as pessoas que me conhecem julgam fazer sentido.
HORA DO ANÚNCIO! 🐵📣
Depois de muito tempo, a página do Steam to do Toada ESTÁ NO AR
Se liga no nosso trailer e deixa seu wishlist no Steam
#jrpg #steam #indiegame
Super Bloom: Fast and precise filter for streaming k-mer queries www.biorxiv.org/content/10.64898/2026.03...
Tira de quadrinhos, 2x2. Primeiro quadro: crianças apontam para um monstro, “um monstro!”, “vai destruir tudo! Segundo quadro: monstro responde “perdão, não quis assustar, estou só de passagem” Terceiro quadro: crianças na frente de um prédio dizendo “casa o carai, é tudo datacenter” Último quadro: monstro e crianças pisando alegremente nos escombros do datacenter
(Mas, claro, todo mundo esperando Godzilla)
Alguns que podem ser úteis:
simonwillison.net/guides/agent...
oxide-and-friends.transistor.fm/episodes/eng...
www.rockoder.com/beyondthecod...
You can now view a tree of 2,399,238 bacterial genomes we made from AllTheBacteria (on the great Taxonium):
taxonium.org/atb
That's a big tree!
(unless you're used to SC2 trees)
usar IA é basicamente estrangular com as proprias mões o wikipedinho . repassem
