Big news for medRxiv users: you can now publish your data on Dryad as part of your preprint submission! 🎉

What happens:
✅upload your research data directly to Dryad when posting your preprint
✅other researchers can build on your findings immediately

Learn more: openrxiv.org/dryad-integr...

✏️ Authors can engage with commentary that helps surface new ideas and strengthen evolving work

🔬 Research groups, journal clubs, and educators gain a structured way to bring active discussion into preprint reading.

Head to a preprint, click on Comment and join the conversation. 💚

Here's what's new:

✅ Refreshed, open-source commenting experience
✅ Author email notifications when the first comment is posted, so no discussion gets missed

📗 Readers can continue to share insights, ask questions, and contribute perspectives directly on bioRxiv & medRxiv preprints.

Preprints thrive when embedded in an active scientific ecosystem 🎉

That's why we're excited to announce updated article-level commenting on @biorxiv-medrxiv.bsky.social, now powered by Hypothesis.

openrxiv.org/hypothesis-c...

#OpenScience #Preprints #bioRxiv #medRxiv

And subscribe here: openrxiv.org/newsletter/?...

The latest edition of Re:Port is live! Check it out and make sure to subscribe to get the latest updates from openRxiv right to your inbox.

openrxiv.org/wp-content/u...

We are thrilled to welcome Dr. Martina Proietti Onori, and Dr. Sanchari Ghosh, Scientific Content Specialists at @openrxiv.bsky.social, the new organizational home for bioRxiv & medRxiv for this upcoming event! 🚀

🔗 Registration is open now: shorturl.at/9yAAt
🗓 April 1st, 2026. 5 pm EST

Subscribe to the openRxiv Re:Port newsletter for the latest news, community updates, and insights from the openRxiv team.

Stay informed & sign up today!

openrxiv.org/newsletter/

#OpenScience #ScholarlyCommunication #Research #Preprints #openRxiv

Versions in action: updating our preprint on preprints - openRxiv bioRxiv and medRxiv were initially an experiment themselves, to see how preprint servers in the life sciences could work and impact science. In that vein, in 2019 we posted a preprint on bioRxiv summa...

See a summary in our blog post: openrxiv.org/updated-prep...

Quantitative survey results on zenodo: doi.org/10.5281/zeno...

Results from a 2023 survey. N=4,042. Horizontal bar chart of percentage of respondents who value preprints for different reasons. Quality, Impact and Discoverability. To increase awareness of your research, 82%. To benefit science, 64.3%. To control when your research is available, 53.5%. To receive feedback, 37.8%. To increase awareness on social media, 32.5%. Credit and acknowledgement. To stake a priority claim, 55.5%. To cite your research in a grant proposal, 47.9%. To cite research progress in a job application, 30%. To cite your research in a tenure application, 12.8%. Recommendations. Principal/Senior Investigator's recommendation, 24.6%. Comply with funding agency's policy, 21.2%. Co-author recommendation, 15%. Other colleague's recommendation, 9.9%. Other, 5.8%.

The survey results meanwhile reveal authors’ motivations for preprinting, when they choose to post, how they receive feedback, and the spectrum of authoring tools used.

#preprints #bioRxiv #SurveyResults

Vertical bar plot of number of new papers and revised papers per year and per month from 2013 to 2025. New papers start around 100 per year in 2013-2014. They increase steadily to about 2500 in 2019, with a spike up to 3800 in 2020. They then decrease to about 3000 in 2022 and rise back up to 4000 in 2025. Revised papers follow a similar trend, with the peak to about 1200 in 2020 a decrease and then to 1500 in 2025.

We include an overview of our technological approach and present data on the growth in submissions, revisions, publication outcomes, revisions, withdrawals, license choices, and adoption across different subdisciplines.

#preprints #bioRxiv

✨ Updated preprint on bioRxiv preprints!

A new version of our preprint summarizes #bioRxiv progress over the last 12 years. This is an update of our original 2019 preprint with new data & highlights from a more recent survey of >7000 users. www.biorxiv.org/content/10.1...

#preprints #OpenScience

The Story behind the Science: Preprints of pandemic potential—how bioRxiv and medRxiv brought preprints to the life sciences | mBio When we launched medRxiv in mid-2019, we never could have anticipated that just a few months later, New York would be at the epicenter of a rapidly escalating global pandemic, and we would be handling hundreds of papers about a previously unknown virus every week. Articles about bioRxiv and medRxiv preprints would appear on the New York Times front page, and our team worked every waking hour, seven days a week, making rapid decisions about sometimes controversial work and disseminating results of COVID research to millions of readers around the globe. Along the way, we were called dangerous and irresponsible by some, wimps and censors by others, but most in the biomedical community valued the service, and even Anthony Fauci and the head of the WHO called attention to the importance of preprints.

@richardsever.bsky.social reflects on the birth of @biorxiv-medrxiv.bsky.social, the crucial role members of the community have played, the experience during the pandemic, & the launch of openRxiv set up to oversee the servers. It truly takes a village.
journals.asm.org/doi/10.1128/...

#OpenScience

In our first year as an independent nonprofit, we grew leadership & collaborations & saw recognition for preprints.

There were also the most new @biorxiv-medrxiv.bsky.social preprints in a year yet! 🎉

Our year in review: openrxiv.org/2025-year-in...

Thank you for continuing to build together. 💚

SciCon 2025 - Panel: Can and Should Academia be Decentralized YouTube video by ResearchHub Foundation

How might academia be decentralized?
openRxiv CEO, @tracykteal.bsky.social, joined leaders from arXiv, Feinstein Institutes, and Mount Sinai to explore what decentralization would mean for science.
Watch: www.youtube.com/watch?v=RlNM... #OpenScience #AcademicPublishing

They'll be in this account!

Why the name 're:Port'? re:Port embodies the dynamic exchange of scientific knowledge - replying to and reporting on emerging research while serving as an open portal where discoveries can flow, accelerating the journey from insight to impact.

We're excited to continue sharing the journey. 💚

Our first issue highlights updates to our DOI, launches of integrations & funder metadata fields, highlights from a recent meeting, and community opportunities.

Read the first issue -> openrxiv.org/wp-content/u...

Introducing the openRxiv re:Port newsletter 📬 🎉

openRxiv's new newsletter = updates on bioRxiv & medRxiv, new initiatives, & community highlights.

Stay connected on what's next in 'communication at the speed of science'.

Subscribe & view the first issue → openrxiv.org/newsletter/

#OpenScience

openRxiv team members are presenting“bioRxiv and medRxiv: The Next Chapter” at Cell Bio 2025!
🗓️ Mon, Dec 8
⏰ 11:15 AM
📍 Room 117
Come hear what’s next for preprints + open research. Don’t miss it!

#CellBio2025 #OpenRxiv #ScienceForward #OpenScience #ResearchCommunity

Promotional flyer for openRxiv at Cell Bio 2025, December 6-10 in Philadelphia, PA, booth #1134, with a background of illustrated cells.

openRxiv is heading to Cell Bio 2025 in Philadelphia 🔬
See us at Booth 1134 with Cold Spring Harbor Laboratory Press from December 6-10. We’re excited to meet the community, share what we’re building, and talk about the future of open science. We hope to see you there.

So today on this #GivingTuesday it's a chance to celebrate + support the people and orgs behind open infrastructure.

Donate, volunteer, amplify—it all counts in supporting and contribute to this work. 💚

#OpenInfrastructure

But here’s the paradox: When infrastructure works, it can be invisible.

The better it functions, the easier it is to overlook, especially when it’s time to show support.

#GivingTuesday #OpenScience

...
@cos.io
@investinopen.bsky.social
@orcid.org
@openalexix.bsky.social

They make collaboration + discovery possible.

#OpenSource #OpenData

Just a few of the quiet champions behind open research are orgs like:

@datadryad.bsky.social
@creativecommons.bsky.social
@prereview.bsky.social
@carpentries.carpentries.org
@pyopensci.org
@ropensci.org
@thecscce.bsky.social
@datacite.org
@crossref.bsky.social
...

Scientific open infrastructure is the invisible backbone of research. It’s what connects scientists across disciplines + borders, builds essential skills, sparks collaboration, and preserves knowledge for future discovery.

#OpenScience #OpenInfrastructure

Photo of a group of 20 people in an open space with windows and desks. People are in a standard group photo pose facing the camera and smiling.

Building trust, building together: In San Diego @continuous.foundation & openRxiv hosted a workshop bringing together developers of scientific communications tools. Implementation focused, and most importantly we got to work together.
Learn more: articles.continuousfoundation.org/articles/sci...

bioRxiv and medRxiv experienced an outage this morning due to the global Cloudflare outage. The sites were unavailable for several hours and may be slow or intermittently unresponsive as services recover. There is no impact on submissions or underlying data. Thank you for your patience.

This pilot expands the @biorxiv-medrxiv.bsky.social review ecosystem alongside bioRxiv/medRxiv to journal transfers, TRiP transparent reviews, @prereview.bsky.social, & @asapbio.bsky.social partnerships.

As preprints decouple dissemination from review, we hope to enable experiments in review.

Founded by molecular biologist @odedrechavi.bsky.social and colleagues, q.e.d. analyzes claims against data, identifies gaps, and highlights original contributions, typically delivering detailed reports for authors in ~30 minutes.