Hard at work deciphering cilia! I am really proud of Nicholas Hadas for being accepted to the PhD program in Bioinformatics at the Francis Crick Institute in the UK.

China turns the tables in biotech For at least a century, major scientific research initiatives have reliably occurred in the United States, usually in response to geopolitical competition. This helped establish the country’s status a...

This is a quick read summarizing what many of us have been seeing the past several years..

www.science.org/doi/10.1126/...

Merry Christmas to all my colleagues. I am thrilled to spend the holiday with a very very dear friend of mine, Dr Kareem Azab, from UT Southwestern. Drinking coffee as only a scientists might understand 😊

I was invited to give talks to 4 separate meetings the past 2 months. However, I am particularly excited to be invited by my former Chief, Tom Ferkol, to present at U of North Carolina. Together with my research mentor, now collaborator, Steven Brody, he is a main reason I work in cilia and PCD.

I am excited to share our latest preprint describing comparative transciptomic analysis between primary ciliary dyskinesia and cystic fibrosis. The more we understand the pathways driving disease the better equipped we are to find a cure.

www.biorxiv.org/content/10.1...

Machine Learning Analysis of Cilia-Driven Particle Transport Distinguishes Primary Ciliary Dyskinesia Cilia from Normal Cilia Rational. Primary ciliary dyskinesia (PCD) is a genetic condition that results in dysmotile cilia and abnormal mucociliary clearance. Despite advances in understanding the pathogenesis of PCD, diagnos...

I am excited to share our preprint on the use of machine learning to identify abnormal cilia function. I am proud of Nicholas Hadas, a talented PhD candidate, for his hard work in compiling the code and preparing this manuscript.
www.biorxiv.org/content/10.1...

I would like to share a Guideline-in-Focus episode that summarizes the recently published ERS/ATS PCD diagnosis guidelines. These guidelines are an important step in standardizing our approach to #PCD diagnosis across the world.

channel.ersnet.org/channel-38-g...

I am excited to share the new PCD diagnostic guidelines.
A great collaboration with PCD experts from all over the world.

publications.ersnet.org/content/erj/...

It is bitter sweet to say goodbye to my patients. Last week was tough for the WASHU PCD and Rare lung team, as we saw 4 patients graduate to the adult side. I had the privilege to care for some for almost 15 years. I am glad to share their journey and be part of their lives.

Congratulations to the winner of the best poster awards and the best flash talks awards at the #OTM2025. Shout out to all the excellent posters on #primaryciliarydyskinesia #PCD.

PCD Foundation On The Move 2025 kicks off in Minneapolis. President Michele Manion welcomes an audience of 200! Exciting times ahead for #PrimaryCiliaryDyskinesia- registries, clinical trials and more! #OTM2025

Incredibly powerful patient panel to counter narrative that PCD is mild- importance of advocacy for care for their own health in a system where PCD is under appreciated. Burden of airway clearance & toll of school, family & work. Trade-offs choice of nebs, commitments & health trade-offs. #OTM2025

Time to celebrate.. the WASHU PCD Time is excited to see it's rank expand. We wish the expecting moms all the best, and we can't wait to meet the little ones.

Amazing accomplishment for Susan Dutcher. A well deserved and overdue recognition #NAS.

I am proud of Nicholas Hadas, a talented bioinformatician @horanilab.bsky.social @wu-ciliopathygroup.bsky.social (and a future PhD candidate) for wining first place in predictive analytics with his group, at the The CAIDF Hackathon in Chicago.

Dutcher elected to National Academy of Sciences Susan K. Dutcher, a professor of genetics and of cell biology and physiology at Washington University School of Medicine in St. Louis, was elected to the National Academy of Sciences in recognition of...

👏👏🙌
source.washu.edu/2025/05/dutc...

I am excited to welcome Shams Neupane, PHD to the Horani lab. I look forward to see what she can accomplish during her postdoc with us.

Looking forward to joining the ERN Lung meeting and discuss science and advanced in PCD with my European colleagues 😊

Genetic analysis explains rare disease severity, points to possible treatment Researchers at Washington University School of Medicine in St. Louis have uncovered why some patients with a rare genetic disorder called primary ciliary dyskinesia have worse lung problems than other...

Genetic analysis explains rare disease severity, points to possible treatment 👇 #ciliopathies #PCD

@dutcherlab.bsky.social @brodylab.bsky.social @horanilab.bsky.social @mahjoublab.bsky.social @washu.bsky.social

source.washu.edu/2025/03/gene...

World wide reach! WashU and our own Susan Dutcher were featured on the cover of Le Monte (Paris) during Stand Up for Science day.

So privileged to work with and alongside a group of thoughtful and amazing scientists at WASHU medicine as part of the @wu-ciliopathygroup.bsky.social with our fearless leaders @dutcherlab.bsky.social and @brodylab.bsky.social and motile cilia group @horanilab.bsky.social and @mahjoublab.bsky.social

Despite the uncertainties over science and research's future now adays, life needs to continue. The WASHU ciliopathy Research group and PCD and Rare lung disease center @washu Medicine is heading to a medical outreach mission to see PCD patients. #PCD #cilia

Steve wanted to relive his postdoc years.. we were glad to oblige : )

Undocking of an extensive ciliary network induces proteostasis and cell fate switching resulting in severe primary ciliary dyskinesia CCDC39 and CCDC40 variants interrupt the motile cilia assembly program, disrupt cilia architecture, and alter motility-independent cell functions.

Excited to share our recent work unraveling the effects of CCDC39/CCDC40 PCD variants on cilia. The result of years of work and collaborations of several members of the @wu-ciliopathygroup.bsky.social research group, lead by @dutcherlab.bsky.social and @brodylab.

www.science.org/doi/10.1126/...

Hello #Bluesky! We'd like to introduce ourselves...

We are the WashU Ciliopathy Research Group - a multidisciplinary team of investigators at Washington University in St Louis that perform fundamental, translational, and clinical research on #ciliopathies.

Follow us for updates from the group! 👇

Aberrant centrosome biogenesis disrupts nephron progenitor cell renewal and fate resulting in fibroc... bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

ACCEPTED! Great way to start a Monday.

Congrats to my amazing postdoc Tao Cheng!!!

Updated version of this coming soon: www.biorxiv.org/content/10.1...