I hate the direction lab equipment design has gone in recent years.

I don't want touchscreens, I don't want wifi integration, I don't want centrifuges demanding to know what time zone they're in.

I just want reliable instruments - with physical buttons - that do the one task they were made for.

Very cool work, Zibo! I remember seeing your presentation at RosettaCon and being fascinated. Congrats!

Stereochemistry in the disorder–order continuum of protein interactions - Nature Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.

We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered???

www.nature.com/articles/s41...

Really liking the "Popular With Friends" feed on BlueSky, just in case people were not aware of it.

🧪 For people interested in AI & enzymes (enzyme engineering, design, discovery, ...), I'm assembling a starter pack for us.

DM if you'd like to be included!

go.bsky.app/MhfaQBh

Two BioML starter packs now:

Pack 1: go.bsky.app/2VWBcCd
Pack 2: go.bsky.app/Bw84Hmc

DM if you want to be included (or nominate people who should be!)