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Posts by Julia Frunzke

It was a good pleasure to host Annegret Wilde @freecyano.bsky.social from @biologyunifreiburg.bsky.social and @sfb1381.bsky.social

To our INSPIRE seminar series @hhu.de with a close interaction between @mibinet.bsky.social and @ceplas.bsky.social

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Congratulations Florian!!
@mibinet.bsky.social

6 hours ago 4 3 1 0

Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !

4 days ago 78 33 0 0
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Trans-Atlantic Platform for Social Sciences and Humanities (T-AP) Call: Preparing for Tomorrow – Societies and Strategies in Times of Transition

#CallForProposals The DFG and the Trans-Atlantic Platform (T-AP) are pleased to announce its 5th international funding call: Preparing for Tomorrow: Societies and Strategies in Times of Transition. Aim of the call, scope and next steps:
www.dfg.de/de/foerderun...

3 weeks ago 9 1 0 0
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Congratulations to Johannes Hartl, Charité Berlin for receiving the 2026 VAAM Research Award for new research findings into the interplay of genes, the environment, and metabolism in microorganisms! ✨

Find more about his research and VAAM press statement on🔗https://t1p.de/2ghut

4 weeks ago 17 3 0 1
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Congratulations to Johannes Hartl (Berlin Institute of Health & Charité), awardee of this year’s VAAM Research Award @vaam-microbes.bsky.social!

4 weeks ago 13 1 1 0

David Botstein wrote one of the most insightful and inspiring papers I’ve read on the evolution of mobile genetic elements. Still very much worth a reading these days. Hard to find people with such diverse, outstanding contributions. nyaspubs.onlinelibrary.wiley.com/doi/10.1111/...

1 month ago 45 7 0 0
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Direktor:in (w/m/d) am Institut für Bio- und Geowissenschaften – Biotechnologie (IBG 1) in kollegialer Leitung am Standort Jülich mit Universitätsprofessur (W3) für Mikrobielle Biotechnologie an der H... Forschungszentrum Jülich GmbH bietet Stelle als Direktor:in (w/m/d) am Institut für Bio- und Geowissenschaften – Biotechnologie (IBG 1) in kollegialer Leitung am Standort Jülich mit Universitätsprofes...

Call for applications: New Director at the Institute of Bio- and Geosciences at @fz-juelich.de, combined with a joint W3 professorship with @hhu.de in "Microbial Biotechnology".

www.academics.de/jobs/direkto...

1 month ago 6 6 0 1
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Logo mit verschiedenen Bubbles und Schriftzug: DFG Chancengleichheit, sowie Hinweis auf den Kurzlink www.dfg.de/chancengleichheit

Logo mit verschiedenen Bubbles und Schriftzug: DFG Chancengleichheit, sowie Hinweis auf den Kurzlink www.dfg.de/chancengleichheit

Mit der einheitlichen CV-Vorlage ermöglicht die DFG u.a. freiwillige Angaben zur "Besonderen persönlichen Situation", wenn sie die Laufbahn >3 Monate beeinflusst hat (Care-Arbeit, Erkrankung, Flucht, eingeschränkte Mobilität etc). So können Leistungen vergleichbarer eingeordnet werden:
sohub.io/wdf5

1 month ago 18 3 0 0

Very excited to see this work out today!

Discovering viral immune antagonists directly from predicted protein structures. 🤩 www.science.org/doi/10.1126/...

Huge thanks to the amazing collaborators! 🤗

1 month ago 24 9 2 0

Amazing resolution of this beautiful mechanism!
@spp2330.bsky.social

1 month ago 6 3 0 0
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🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process.
www.biorxiv.org/content/10.6...

1 month ago 104 37 6 6
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Mathematisch-Naturwissenschaftliche Fakultät Heute ernannte Rektorin Prof. Dr. Anja Steinbeck den Biotechnologen Dr. Johannes Rebelein zum W3-Professor für Nachhaltige Biotechnologie. Rebelein wird damit auch Direktor des Instituts für Molekular...

Welcome to our new colleague Johannes Rebelein, head of the Institut of Sustainable Biotechnology @hhu.de and our new colleague at the Institute of Bio- and Geosciences 1 @fz-juelich.de.
Welcome to @mibinet.bsky.social!

www.chemie.hhu.de/en/latest-ne...

1 month ago 24 5 4 2

Fantastic collaboration w/ @dbikard.bsky.social @audeber.bsky.social @rayanchikhi.bsky.social labs led by @jmouradesousa.bsky.social : We assessed the rates of variation of anti-phage systems in P4-like satellites and P2 helper phages. Quick conclusion: Huge variation! We focus on 4 key questions/5

1 month ago 48 22 1 1
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Save the date for the next International Conference on Gram-Positive Bacteria which will take place between 29 June–2 July 2027. The organizers (@annadragos.bsky.social, @polonca32.bsky.social, and Ines Mandic-Mulec) look forward to welcoming you to Ljubljana, Slovenia

1 month ago 17 10 1 0

@spp2330.bsky.social

1 month ago 2 1 1 0
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New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

1 month ago 53 50 5 4
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Assistant/Associate/Full Professor Computational Biology Assistant/Associate/Full Professor Computational Biology

Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social

Application deadline on 15 March 2026
👇
careers.universiteitleiden.nl/job/Assistan...

1 month ago 21 22 0 0

Cell death is a fundamental mechanism of antiviral immunity across diverse organisms, including bacteria. As my final PhD project with @jbdsf.bsky.social, I was curious whether cell death is required for successful immunity with the ancient cGAS pathway known as ‘CBASS.’

Spoiler – the answer is no!

1 month ago 36 14 2 2

Glückwunsch Lena!

1 month ago 4 0 0 0
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Please RT:
Looking forward to our International Symposium on "Microbial Networking - from organelles to cross-kingdom communities".
Highlight of our first funding period of our Collaborative Researc Center @mibinet.bsky.social, @dfg.de

www.sfb1535.hhu.de/mibinet

@hhu.de , @fz-juelich.de

2 months ago 10 9 1 0
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Lasse presents our CRC1535 MibiNet project at the first RNA confluence meeting at the EMBL.
@rhinelandrna.bsky.social @mibinet.bsky.social

2 months ago 7 3 0 0
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PhD advertisement - Pausch lab | Patrick Pausch | 15 comments Please share! 📤 The Pausch lab at Vilniaus universitetas / Vilnius University is looking to recruit PhD students to work on: ⚔️ 🛡️: Bacterial Immune Systems (CRISPR, retrons, & beyond) 🧬 ✂️: De...

Great opportunity to join the lab of @patrick-pausch.bsky.social !

www.linkedin.com/feed/update/...

2 months ago 5 5 0 0
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Save the date, please RT:

Looking forward to an exciting International Symposium @spp2330.bsky.social "New concepts in prokaryotic virus-host interactions".

October 5-7, 2026; Harnack-Haus Berlin (Germany).

@dfg.de @hhu.de @fz-juelich.de

3 months ago 29 19 1 0

Congratulations! Nice to see this published!

3 months ago 1 0 0 0
A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

3 months ago 10 8 1 0
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Great collaboration with @hoeferlab.bsky.social, @aharms485.bsky.social, @pozhydaieva.bsky.social, @usadellab.bsky.social, @vivienrosenthal.bsky.social

3 months ago 6 1 0 0

This shows that "abortive infection" phenotypes are not neccessarily in all cases a "last line" of defense, but may be the consequence of mechanisms interferring with early steps in the phage life cycle.
We further show synergy of daunorubicin with RM systems targeting the FST region T5 phages.

3 months ago 3 1 1 0
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Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"

www.biorxiv.org/content/10.6...

@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social

3 months ago 44 26 2 0
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Postdoc (m/f/d) in Endosymbiosis Research

📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!

4 months ago 24 35 0 0