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Posts by Aaron Guinn

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Developing and Evaluating LLM-Generated Emergency Medicine Handoff Notes This cohort study evaluates large language model (LLM)–generated emergency medicine–to-inpatient handoff notes and evaluates their accuracy and safety compared with physician-written notes.

Kudos to this study team using LLMs to write ED handoffs. Gen AI notes scored better on automated measures, but a bit lower on physician review. Zero critical safety issues, but a few issues with logic/completeness. Smart new framework for safety eval. #EMedSky

jamanetwork.com/journals/jam...

1 year ago 3 1 0 0
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Dissection and dissecting aneurysms of the aorta: twenty-year follow-up of five hundred twenty-seven patients treated surgically - PubMed Dissection and dissecting aneurysms of the aorta: twenty-year follow-up of five hundred twenty-seven patients treated surgically

It’s a a bit of an outdated term, but it is a proper medical term. Whether it’s accurate here is a separate issue. Here’s DeBakey writing about it: pubmed.ncbi.nlm.nih.gov/7147190/

1 year ago 1 0 0 0
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A Randomized Trial Comparing Inhaled Insulin Plus Basal Insulin Versus Usual Care in Adults With Type 1 Diabetes OBJECTIVE. To evaluate a regimen of inhaled Technosphere insulin (TI) plus insulin degludec in adults with type 1 diabetes, who prestudy were predominately

A regimen of inhaled insulin plus basal insulin showed similar HbA1c outcomes compared to usual care for type 1 diabetes patients.

by Hirsch IB, Beck RW (...) Calhoun P et 37 al. in Diabetes Care #MedSky

📖 read the article:

1 year ago 16 3 0 0
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You’re never too busy to show kindness to a child.

When this preschooler showed up for a race (on his pedal-less strider bike) at the local BMX park, his family discovered that he was the only one in his age group to attend.

(Thread 🧵)

1 year ago 149 24 5 5
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Ingestion of gelatinous candy, mimicking acute gastric bleeding A detailed medical history is vital in the correct interpretation of medical images: Peer‐to‐peer feedback and a thorough medical history can help avoid diagnostic pitfalls and unnecessary therapy. Ke...

One of my favorite case reports. Includes 3D reconstruction CT images of a bag of gummy bears 😂

pmc.ncbi.nlm.nih.gov/articles/PMC...

1 year ago 0 0 0 0

Interesting result…

>Importantly, despite mortality benefit for the entire patient population studied, the authors found no effect of the intervention on mortality for patients with an alert, raising the possibility that the intervention was exerting broader effects on care patterns

1 year ago 1 0 0 0

Hope to be there if life permits!

1 year ago 3 0 0 0
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It’s like a Platonic solid just with less albumin usually.

1 year ago 1 0 1 0
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Does Andexanet Alpha Improve Outcomes Compared With Four-Factor Prothrombin Complex Concentrate for Reversal of Direct Oral Anticoagulants? www.annemergmed.com/article/S019... #education #MedSky #MedTwitter #EMSky #EMedSky #BlueSky

1 year ago 6 3 0 0

I’ve used it sporadically over the years. It seems to work a solid “meh.” It does a bit but isn’t saving the day. Honestly once I learned that you can give up to 80-100mg of IV maxuran, Ive almost never had to use anything other than maxuran and NSAIDs for about 10 years now.

1 year ago 1 0 1 0
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Splash pads really are fountains of fecal material; CDC reports 10K illnesses A big problem is leaky swim diapers and kids sucking up recirculated water.

Between 1997 and 2022, splash pads across the country were linked to at least 60 outbreaks, with the largest sickening over 2,000 water frolickers in one go.

1 year ago 98 34 7 17

Antipsychotics are used to treat *agitation* in dementia when non-pharmacological attempts don’t work and there are concerns the patient may hurt themselves or someone else. This is standard practice supported by both Canadian and international guidelines. Ex: ccsmh.ca/wp-content/u...

1 year ago 0 0 0 0

There’s nothing about daily fines, or restricting students from moving out of province. The bill is here: m.assnat.qc.ca/Media/Proces...

1 year ago 0 0 0 0

The actual text of this tabled bill is extremely different than what is suggested in this article. It basically establishes fines for MDs who bill for publicly covered services within the first 5y of practice, and allows the government to create a RoS agreement with students.

1 year ago 0 0 0 0
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Happy Friday!
Just going to leave this here and hopefully put a smile on one or two faces 😀

Our hospital greeter
#dogtherapy #MedSky

1 year ago 6 1 0 0
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Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury This randomized clinical trial assesses the effect of a liberal vs a restrictive hemoglobin threshold for red blood cell transfusion on unfavorable neurological outcome in patients with acute brain injury.

A liberal transfusion strategy in acute brain injury patients leads to better neurological outcomes than a restrictive approach.

by Taccone FS, Rynkowski Bittencourt C (...) Vincent JL et 25 al. in JAMA

📖 read the article:

1 year ago 3 2 0 0

Improves cognitive performance too, right??? #medsky

1 year ago 3 0 0 0
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Hot off the Press: Enhancing Emergency Department Triage Equity With Artificial Intelligence: Outcomes From a Multisite Implementation www.annemergmed.com/article/S019... #education #MedSky #EMSky #EMedSky #BlueSky

1 year ago 4 3 0 1
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Predicting troponin biomarker elevation from electrocardiograms using a deep neural network Background Elevated troponin levels are a sensitive biomarker for cardiac injury. The quick and reliable prediction of troponin elevation for patients with chest pain from readily available ECGs may p...

#news "The model exhibited clinically meaningful performance, notably its high negative predictive accuracy"

"Clinical use of comparable #AI in first-line, quick-response triage of patients with chest pain or dyspnoea appears as a valuable option" #emedsky #medsky
openheart.bmj.com/content/11/2...

1 year ago 2 2 1 0
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Health system-wide access to generative artificial intelligence: the New York University Langone Health experience AbstractObjectives. The study aimed to assess the usage and impact of a private and secure instance of a generative artificial intelligence (GenAI) applica

NYU gave their staff access to HIPAA-secure ChatGPT last year. It's a pretty great paper looking at real-world usage of GenAI. If you run the numbers, you could arguably give healthcare users access for like $20 a year, which seems kind of mind-blowing to me.

academic.oup.com/jamia/advanc...

1 year ago 10 6 2 0
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Skytorial: can you crack the case?

A middle-aged healthy patient undergoes colonoscopy under propofol sedation.

Colonoscopy is unremarkable.

Post-procedure, the patient doesn't wake up and has rhythmic movements involving the legs as shown here.

Labs are normal.

What might be going on?

1 year ago 95 33 5 6
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Insights into durability against resistance from the antibiotic nitrofurantoin - npj Antimicrobials and Resistance npj Antimicrobials and Resistance - Insights into durability against resistance from the antibiotic nitrofurantoin

📣 New perspective paper: Insights into durability against resistance from the antibiotic nitrofurantoin

We discuss what makes nitrofurantoin robust against resistance evolution, in spite of prolonged and extensive usage against UTIs #MicroSky

Open access/CC-BY-4.0: www.nature.com/articles/s44...

1 year ago 71 37 7 4
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Achieving optical transparency in live animals with absorbing molecules. @science.org #scisky #Medsky #News #Technology

Read more
www.science.org/doi/10.1126/...

1 year ago 6 1 1 0

Interesting. Definitely had been taught to avoid cephalexin in pyelo. Our lab still comments on urine cultures that it’s not appropriate to use to treat pyelo. #medsky #emedsky

1 year ago 3 0 0 0
A photograph looking down on a larval insect. You can see a rounded head at the top and the fluffy tapered bottom. Between these are six segments, alternating white and black. There are hairs coming off of the six black segments, but not the shiny white segments between them.

A photograph looking down on a larval insect. You can see a rounded head at the top and the fluffy tapered bottom. Between these are six segments, alternating white and black. There are hairs coming off of the six black segments, but not the shiny white segments between them.

#EntomologyConsult: A patient has a persistent rash. Concerned about insects are the cause, looked through the bedroom and found these. Would these have caused the rash?

1 year ago 4 3 2 0
Yes I am a pink axolotl deal with it

Yes I am a pink axolotl deal with it

Sometimes, you just need to bow to the absurd a little bit…

1 year ago 1 0 0 0

Equally applicable in my line of work! #emedsky

1 year ago 4 1 1 0
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Your baby may be able to sit upright without assistance as early as 6 months, but, like most skills, this is one perfected over time.

This happy little guy is almost there. It’s hard when Dad has more jokes than you have balance and core strength!

(Thread 🧵)

1 year ago 196 20 9 5
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Your energy affects everyone around you. 😄

1 year ago 2493 586 77 51
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“Check”

1 year ago 496 35 0 2