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Posts by Jaroslav Icha

21st century dev bio at its best! I can't help but point out that not one but two Bruker microscopes (Acquifer IM, MuVi) were used for gentle&long term time lapse imaging of developing Nematostella here. No need to mount your invertebrate (cnidaria, planaria, crustaceans), we can do the time lapse!

2 days ago 4 1 0 0

Now published. Congrats to Soham and all co-authors! www.science.org/doi/10.1126/....
@embl.org

3 days ago 52 20 2 1

program and registration: www.bruker.com/en/news-and-...
Perhaps not the most convenient time for EU, where most people, who will see this post, live. However, one can always go back to the recordings.

1 week ago 0 0 0 0

The relevant technologies featured are our benchtop multiphoton microscope Ultima 2P Plus, the range of Inscopix miniscopes and the superresolution Vutara VXL microscope.

1 week ago 0 0 1 0
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Like last year, we are running an online Bruker Fluorescence Microscopy neuroscience miniconference. It is focused on the actual science one can do with our microscopes presented by researchers, not sales presentations.

1 week ago 1 0 1 0

We are looking for an experienced light microscopy specialist, motivated to support our users in the Advanced Light Microscopy Facility at EMBL Heidelberg.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j... -closing date 11 May 2026 @eurobioimaging.bsky.social @globalbioimaging.bsky.social

1 week ago 35 35 0 2
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Don't miss it! We will present several different imaging modalities popular among zebrafish researchers #lightsheet #HCS #screening

2 weeks ago 0 0 0 0
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I suppose most EU zebrafish researchers will attend European zebrafish meeting in July in Vienna #EZM2026. It is going to be a great event like the previous one in Krakow.

Important note for you: Come early, already on 6th in the evening. The conference starts with Bruker Luxendo workshop on 7th.

2 weeks ago 1 0 1 0

Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex...
@embl.org

1 month ago 140 64 5 3
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Interesting points:
📌max projection on the fly to see what's going on
📌data compression helps hugely (zeroing the background, especially if your sample takes up only a small part of FOV)
📌not only processing, also "just" visualization of a 4D lightsheet dataset is non-trivial
So, go and listen.

1 month ago 0 0 0 0
Image Analysis in Light-Sheet Microscopy: Big Data Processing, Handling, and Storage
Image Analysis in Light-Sheet Microscopy: Big Data Processing, Handling, and Storage YouTube video by Bruker Fluorescence Microscopy

Whoever tried some lightsheet microscopy knows that image acquisition is the fun easy part. The real challenge comes later.
This @brukercorporation.bsky.social Luxendo podcast episode touches on the real challenges.
www.youtube.com/watch?v=tAjl...

1 month ago 8 2 1 0
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Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - FocalPlane Spider-like neurons finding their way: signposts for multipolar migration in the developing brain - News

📢New behind the paper story

Using the #zebrafish retina as a model, Jaakko Lehtimäki
@jalehtimaki.bsky.social, Caren Norden
@nordenlab.bsky.social & team dissect multipolar migration in the developing brain. In this post, Jaakko takes us through their research.

1 month ago 22 5 0 2

Lovely perspective on the recent paper by @nordenlab.bsky.social, written by first-author (and former Postdoc) @jalehtimaki.bsky.social 🐟

🔗 to feature: focalplane.biologists.com/2026/03/11/s...
🔗 to original research paper ICYMI: www.sciencedirect.com/science/arti...

1 month ago 3 1 0 0

New work from Metz Lab @ribesresearch.bsky.social 🐟

🔗 to paper: journals.biologists.com/jeb/article/...

1 month ago 4 1 0 0
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If you are going to the 1st German Fish Model Research Meeting" in Heidleberg in September, consider signing up for Bruker workshop. The registration is already open.

We will cover high throughput screening as well as time-lapse imaging on a lightsheet.

www.bruker.com/en/news-and-...

1 month ago 1 1 0 0
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Acquifer HIVE: The Next Generation of Big Data Management for Microscopy This Bruker webinar introduces the Acquifer HIVE, a centralized data storage and computing solution for processing, analyzing, and visualizing scientific data.

The HIVE underwent quite some upgrades so we are running a webinar to introduce them. If big microscopy data is something you are dealing with, do consider joining. 👇
www.bruker.com/en/news-and-...

1 month ago 1 0 0 0
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One of the Bruker FM products I sell to light microscopists is a server for image processing and storage, the HIVE.
>150 mainly imaging facilities over the years thought it is a good idea to get a HIVE and I'm sure they still do. Even the first installs now 10 years old are mostly still running.

1 month ago 2 0 1 0

But jokes aside, this will be a condensed value proposition directly from my colleague who is building these. So if big data is something you are dealing with, I recommend to join and get all the info and insights first hand.

2 months ago 0 0 0 0
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I talked about this server for image processing and storage to all microscopists that were willing to listen (also to those not refusing too actively).
HIVE underwent an upgrade for next generation hardware. So it is time for everyone's favorite pastime activity...a webinar! goto.bruker.com/4aCYm0J

2 months ago 0 0 1 0
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Featured image with Jan Martinek - FocalPlane Featured image with Jan Martinek - News

focalplane.biologists.com/2026/02/13/f...

2 months ago 0 0 0 0

For whoever going to BonnBrain in March, consider extending your stay by one day and participate in our hands-on! workshop.
Imaging neuronal activity with Inscopix 2P miniscope and voltage imaging with the Ultima 2P Plus multiphoton microscope.
www.bruker.com/en/news-and-...

2 months ago 2 1 0 0
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Expansion Microscopy Has Transformed How We See the Cellular World | Quanta Magazine How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.

Eye candy: article about expansion microscopy of protists.
www.quantamagazine.org/expansion-mi...
Unicellular eukaryotic diversity is often overlooked but I'm thankful it was part of curriculum during my undergrad in Prague. There is exciting and weird cell biology going on in different protists.

2 months ago 0 0 0 0
Nanodiamonds for spatial resolution benchmarking in two-photon microscopy Reliable and reproducible measurement of spatial resolution is essential for validating and comparing the performance of two-photon microscopy systems. We present fluorescent nanodiamonds as robust, photostable, reusable, and biocompatible probes for benchmarking spatial resolution. Owing to their nanoscale dimensions and stable fluorescence, nanodiamonds act as near-ideal point-like emitters, enabling accurate characterisation of the point spread function across varying imaging conditions. We demonstrate that nanodiamond-based phantoms serve as a reliable alternative to conventional fluorescent beads embedded in agarose, while at the same time offering advantages in stability and optical properties. Our results position nanodiamond phantoms as a next-generation calibration material that bridges ease of use and reproducibility, advancing quantitative imaging and cross-platform comparability in modern fluorescence microscopy. ### Competing Interest Statement The authors have declared no competing interest. Wellcome Trust, https://ror.org/029chgv08, Investigator Award in Science 220277/Z20/Z European Research Council, https://ror.org/0472cxd90, ERC-StG “NeuroVisEco” 677687, ERC AdG “Cones4Action” covered under the UK’s EPSRC guarantee scheme EP/Z533981/1 UK Research and Innovation, https://ror.org/001aqnf71, BBSRC, BB/R014817/1, BBSRC, BB/W013509/1 International Human Frontier Science Program Organization, https://ror.org/02ebx7v45, RGP001/2025 Leverhulme Trust, https://ror.org/012mzw131, PLP-2017-005, RPG-2021-026, RPG-2-23-042 Lister Institute of Preventive Medicine Gdańsk University of Technology, https://ror.org/006x4sc24, Nobelium DEC-4/1/2024/IDUB/I.1a/No, Platinum 1/1/2025/IDUB/I.1B/Pt

1/10 New preprint on bioRxiv
Nanodiamonds for spatial resolution benchmarking in two-photon microscopy

We introduce nanodiamond-based phantoms as a robust, reusable alternative to bead–agarose samples for PSF calibration.

www.biorxiv.org/content/10.6...

3 months ago 6 5 1 0
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Deadline for abstract submission in one week!

I'm sharing this reminder because right after the conference we have an open demo day at DZNE Bonn, which will include voltage imaging on Bruker 2P microscope and Ca imaging in freely moving mice with Inscopix miniscopes
www.bruker.com/en/news-and-...

4 months ago 3 0 0 0
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We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes.
📅 March 26th 2026
📌 DZNE in Bonn
Whole day event with hands on sessions, presentations and discussions with our existing 2P users.

Register: www.bruker.com/en/news-and-...

4 months ago 2 1 0 0
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We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes.
📅 March 26th 2026
📌 DZNE in Bonn
Whole day event with hands on sessions, presentations and discussions with our existing 2P users.

Register: www.bruker.com/en/news-and-...

4 months ago 2 1 0 0

We (Bruker Fluorescence Microscopy) will run a satellite event on March 26th. A mixture of a hands on demo of our 2P and miniscopes and our user meeting.
One can attend independently of the conference, so this is a free event for anyone who can make a daytrip to Bonn.
www.bruker.com/en/news-and-...

4 months ago 2 0 0 0
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First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.

4 months ago 3 1 1 0
Flyer advertising the BonnBrain Conference 2026, "From Genes to Circuits and Behavior".

Flyer advertising the BonnBrain Conference 2026, "From Genes to Circuits and Behavior".

Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!

7 months ago 33 22 1 1