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Posts by Alan Rogers

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Biologists Confirm Not Much Evolution Happened Today STANFORD, CA—Calling it a “pretty slow one” as far as natural selection and genetic drift were concerned, biologists from Stanford University confirmed Tuesday that not much evolution happened today. ...

Biologists Confirm Not Much Evolution Happened Today — theonion.com/biologists-c...

5 days ago 47 15 2 1

Morez Jacobs et al used 45k genomes to localize Neandertal haplotypes w/i the British; used these to infer the SFS of the introgressing Neandertals; and then inferred population history parameters of the introgressing pop. Also lots about selection. www.biorxiv.org/content/10.6...

1 week ago 4 1 0 0

Population replacement in Neolithic France at the end of the megalith period. scholar.google.com/scholar_url?...

2 weeks ago 0 0 0 0

The Neanderthal population history and the introgression landscape inferred from the UK Biobank www.biorxiv.org/content/10.64898/2026.04...

2 weeks ago 10 4 0 0

This is the most delightful thing I’ve ever read

2 weeks ago 2585 342 81 16
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A few years ago, using palaeoproteomics, we identified a tiny hominin bone from Denisova Cave and named it Denisova 17 (D17).

A rather unremarkable sliver.

At the time, I wondered, could it be Denny’s sibling (the Neanderthal/Denisovan hybrid we had just reported)?

Well, turns out: no. 🧵1/4

2 weeks ago 57 22 3 0
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This is my favorite climate change chart. Japanese monks, aristocrats, and emperors kept meticulous records of cherry blossom festivals for 1,200 years and accidentally built the world's longest climate dataset.

2 weeks ago 18121 6866 168 254

“Human ancestors interbred with two distinct populations of distant relatives” nice new preprint by @alanrogers.bsky.social @colinmbrand.bsky.social @timwebster.bsky.social showing that “archaics” & “moderns” interbred with two distinct “superarchaic” populations
🧪🧬💀

3 weeks ago 15 7 2 0
Graph showing history of human population size, separation, and gene flow over past 1.5 Ma.

Graph showing history of human population size, separation, and gene flow over past 1.5 Ma.

Can anyone tell me what software makes graphs like this (from Cousins, Scally, and Durbin 2025)?

3 months ago 4 1 2 0
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Welcome to Minnesota, fuckers. Also this is super disturbing because the ICE agent's assault rifle appears to fire as he falls down.

This was filmed by a friend near Chicago and Lake last night.

3 months ago 10293 3176 723 837
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BOMBSHELL: Russia Was Planning a Massive Terrorist Attack on Europe and the U.S. in 2024 Shocking new story out of The Financial Times (paywalled) that supports a BBC report from last year: Russia has been conducting a terror war against the rest of Europe for years. Assassinations, acts ...

"Trump’s National Security Strategy made one thing brutally clear and that is that the United States is no longer fully shaping its own foreign policy. The document reads like parts of it were written in Moscow and stamped in Washington." www.dailykos.com/stories/2025...

4 months ago 3 1 0 0

I often restrict sample of loci to those with identical alleles in reference genomes of two outgroup species, chimpanzee and gorilla. But if N of species A is large, different individuals should differ in difference to B.

4 months ago 2 0 0 0

@peercommunityin.bsky.social is one solution to this problem. We should all support it. #peercommunityin

4 months ago 2 0 0 0
Biol 5221: Human Evolutionary Genetics

Here's a link to the website of this course as hosted by the University of Utah: content.csbs.utah.edu/~rogers/tch/...

4 months ago 8 3 0 0
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GitHub - alanrogers/popgen: A course on population genetics A course on population genetics. Contribute to alanrogers/popgen development by creating an account on GitHub.

I taught (and co-taught) a course on human population genetics from 2000-2024. Having retired, I'm now making all the course materials public: github.com/alanrogers/p... #popgen #evbio

4 months ago 285 103 5 0

#popgen #evbio

5 months ago 2 1 0 0

Maybe so. The estimated rate of M>N gene flow is lower than that in the other direction, but it would surely contribute.

5 months ago 1 0 1 0

#popgen #evolgen

5 months ago 2 0 1 0
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Measuring the Phylogenetic Information in Proteins

How much phylogenetic information is in a small sample of proteins? Pastramanis et al answer this question and also discover a puzzle: each protein added to an analysis of modern and archaic humans increases support for a single implausible hypothesis. evolbiol.peercommunityin.org/articles/rec...

5 months ago 6 2 1 1
A post from Donald Trump reads: “Senator Cryin’ Chuck Schumer is demanding over One Billion Dollars in order to approve a small number of our highly qualified nominees, who should right now be helping to run our Country. This demand is egregious and unprecedented, and would be embarrassing to the Republican Party if it were accepted. It is political extortion, by any other name. Tell Schumer, who is under tremendous political pressure from within his own party, the Radical Left Lunatics, to GO TO HELL! Do not accept the offer, go home and explain to your constituents what bad people the Democrats are, and what a great job the Republicans are doing, and have done, for our Country. Have a great RECESS and, MAKE AMERICA GREAT AGAIN!!!”

A post from Donald Trump reads: “Senator Cryin’ Chuck Schumer is demanding over One Billion Dollars in order to approve a small number of our highly qualified nominees, who should right now be helping to run our Country. This demand is egregious and unprecedented, and would be embarrassing to the Republican Party if it were accepted. It is political extortion, by any other name. Tell Schumer, who is under tremendous political pressure from within his own party, the Radical Left Lunatics, to GO TO HELL! Do not accept the offer, go home and explain to your constituents what bad people the Democrats are, and what a great job the Republicans are doing, and have done, for our Country. Have a great RECESS and, MAKE AMERICA GREAT AGAIN!!!”

The Art of the Deal.

8 months ago 197 43 67 6

Troff came before TeX, at least in my life. But yes, it was wonderful.

8 months ago 2 0 0 0

Thanks. I'll look at your preprint.

9 months ago 1 0 0 0

Very interesting. 2 questions: 1. How large are samples from A and B? 2. Can the result be expressed in terms of a molecular clock instead of a drift clock? A drift clock is usually needed only when one doesn't know which allele is ancestral.

9 months ago 0 0 1 0

Over multiple generations, you need to account for changes in p_i q_i. If the initial p is near 1/2, then pq changes much less than p does, so you can ignore changes in p_i q_i over short intervals.

9 months ago 1 0 0 0

In daughter population i, one generation of drift adds a random increment to allele frequency with mean 0 and variance p_i q_i/2n. These increments are independent, so the between-daughter variance would be twice this value.

9 months ago 1 0 1 0

If I understand you correctly, 1/2n, where n is sample size. But why do we need 2 samples? The Fst of each sample relative to the pop is 1/2n.

9 months ago 0 0 1 0
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He doesn’t remember nominating Jerome Powell.

9 months ago 12290 4119 1001 550

Fuck it, they killed him live.

9 months ago 12689 2889 732 236
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This is the consequences when we chose the wrong
direction.

9 months ago 18790 7897 1710 893
NEVER HAVE I SEEN A MORE APT NATURAL ANALOGY TO THE CURRENT MAJORITY OF THE U.S. CONGRESS.
olors
Nature
The sea squirt digests its own brain after attaching to a rock: Once it finds a permanent home, it no longer needs to think or move.

NEVER HAVE I SEEN A MORE APT NATURAL ANALOGY TO THE CURRENT MAJORITY OF THE U.S. CONGRESS. olors Nature The sea squirt digests its own brain after attaching to a rock: Once it finds a permanent home, it no longer needs to think or move.

My old lady neighbor who texts me memes all day is my new favorite person

9 months ago 121 35 3 3