This is a big advance, folks. We've never had a disease-modifying drug for this devastating inherited disease
www.science.org/content/arti...
www.washingtonpost.com/health/2025/...
www.economist.com/science-and-...
Never thought this would happen in my lifetime.
youtu.be/bhExSMZt1zs?...
It turns out the immune system is playing 4D chess while we thought it was just playing checkers. Using #spatialtranscriptomics from @10xgenomics.bsky.social and @vizgen.bsky.social we were able to peek into the secret lives of tissue resident T cells in the gut as they form after infection 1/n
FastReseg: using transcript locations to refine image-based cell segmentation results in spatial transcriptomics, from Broker Spatial Biology, former NanoString
www.biorxiv.org/content/10.1...
@pkrugman.bsky.social how does it feel to hang it up after 25 years? As a member of the life sciences, I’ve benefited from the crisp and succinct arguments you have put in your columns. Definitely shaped how I communicate as a physician and as a scientist. Thanks a million!
Kudos to Vince Luca and the other laboratories for this achievement! Notch signaling is critical to epithelial, cancer, and T cell biology!
www.moffitt.org/research-sci...
What’s it gonna be?
Colleagues:
We have one unfilled position for July 2025 in our ID fellowship program at Medical College of Wisconsin in Milwaukee. Interested candidates please DM me or email at id_info@mcw.edu.
#IDSky
#MedSky
Please amplify 🙏🙏
www.mcw.edu/departments/...
For all of those in the lung organoid field, add 100ug/mL holotransferrin to your growth media to boost your human adult AT2 cultures. Great example of how serendipity in a mouse model yields insight into human biology.
New in @natureportfolio.bsky.social from the Tuomas Tammela Lab: how aging suppresses tumorigenesis and stemness in the lung by promoting functional iron insufficiency in the alveolar epithelium. Interestingly, this renders aged cells resistant to ferroptosis. #OncSky www.nature.com/articles/s41...
Same
Durvalumab now FDA approved for limited stage #SCLC based on the phase III ADRIATIC trial showing a PFS and an OS benefit (HR 0.73) with 2y of durvalumab after completion of definitive chemoradiation (avoid concurrent use). #LCSM #OncSky
www.targetedonc.com/view/durvalu....
Hi everyone, for giving Tuesday I have set up a patient fund for assistance with the basics to complete curative intent cancer treatments. My patients often have incomplete treatments due to transportation or food issues, despite being fully insured. DM me if you can help! Repost to spread the word!
When Susan was diagnosed with lung cancer we quickly learned we had many unanswered questions. We launched the @23andme Lung Cancer Community with the intention of getting answers.
23andme.com/lung-cancer/
As we embark on Thanksgiving week I want to take a moment to reflect on this year and my family. Unfortunately I lost my sister to lung cancer in August.
blog.youtube/inside-youtu...
Thanks! This is a great resource!
Mind if I'm included?
Congrats!
16%? I've heard 5% and recently 7% from @ryangentzler.bsky.social . Are numbers going up or it depends on where we look?
What do we need to do to achieve parity with mammograms? @ryangentzler.bsky.social
www.nature.com/articles/s41...
Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Ironically I recall a major motivation for Musk's acquisition of Twitter was to reduce censorship and promote free speech.
The unknown factor you didn't account for going to ruin your experiment
If interested in this list mark it 📌
Nailing down risk in early stage breast cancer —with @coffeemommy.bsky.social and Dr. Kevin Kalinsky #OncSky #MedSky
doi.org/10.1093/jnci...
Figure 3. Percentile as a discriminator of high productivity versus low productivity
