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Posts by Manuel San Silvestre, MD
Postdoctoral openings to investigate how (i) experience-dependent actuators of inhibitory circuit plasticity mechanisms & neurogenesis contribute to memory operations (ii) how a novel lipid signaling mechanism mediates cognitive resilience and regulates healthspan. www.sahaylab.com/publications
Hi! Here a prospective Oxford PhD student on the electrophysiological signature of the cognitive cerebellum. I’d love to join the seminars.
He’s too good! A great example of how discipline pays off in any field.
El científico español Mariano Barbacid ha encontrado la cura del cáncer de páncreas.
"Si no se investiga no se avanza".
El Premio Nóbel ya tiene dueño.
As a student, this is very cool!!
An image of Professor Clare Mackay, Professor of Neuroscience, with a quote from her saying: "Many of us with BFRBs know that shame plays a huge role, so it is no surprise that it shows up strongly in this group. What is important is that we have demonstrated that shame is already prevalent in young people aged 13-18, and that it strongly relates to depression and anxiety.”
🔊NEW RESEARCH: Shame plays a major role in hairpulling, a type of body-focused repetitive behaviour (BFRB), among young people, according to a study by @ox.ac.uk
Read more 👉 tinyurl.com/ajjxz7rz
@claremackay.bsky.social @pollywaite.bsky.social #BFRBs @acamh.bsky.social @oxhealthbrc.bsky.social
The ApoE2, longevity & cognitive resilience triad raises the tantalizing (& least understood relationship) possibility that cognitive resilience may promote lifespan, as suggested by cognitively resilient centenarians (100-plus study). Identities of mechanisms remain elusive. 1/2
would result in a DG optimized to flexibly recruit new neurons to generate distinct representations. GABAergic inhibition-dep. reduction of interference btw memory indexes preserved their integrity. This study explains how this obviates need for pattern separation.
www.nature.com/articles/s41...
With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.
My hope is that this will be a living document, continuously improved as I get feedback.