Engineering blood–brain barrier microphysiological systems to model Alzheimer's disease monocyte penetration and infiltration Alzheimer's disease (AD) is a progressive and neurodegenerative disease, predominantly causing dementia. Despite increasing clinical evidence suggesting the involvement of peripheral immune cells such...

New collaborative paper by #IUStemCell members Feng Guo and Scott Canfield, "Engineering blood–brain barrier microphysiological systems to model Alzheimer's disease monocyte penetration and infiltration"

pubs.rsc.org/en/content/a...

Alcohol diminishes barrier integrity in human stem cell-derived brain microvascular endothelial cells: Role of reactive oxygen species The World Health Organization has linked alcohol consumption to over 200 diseases including neurodegenerative diseases. A dysfunctional blood–brain ba…

Check out the latest research from the lab of #IUStemCell member Scott Canfield! In this study, they demonstrate that excessive alcohol levels impair the integrity of the blood-brain barrier in human stem cell-derived models, contributing to the onset or worsening of neurological disorders.

Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids Guo and colleagues developed vascular network-inspired diffusible (VID) scaffolds for engineering midbrain organoids, providing a versatile technology for organoid development and therapeutic innovati...

Congratulations to Feng Guo and his lab for their recent exciting publication in @cp-cellstemcell.bsky.social where they pursue the use of diffusible scaffolds for functional maturation of midbrain organoids! Very cool work!

Happy to have hosted an informational session from @miltenyibiotec.bsky.social today! Great turnout to hear about some of the latest tools for stem cell research

@iustemcell.bsky.social representing at the Wisconsin Stem Cell Symposium today! #IUStemCell