DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active state complexes and deep learning embeddings G protein-coupled receptors (GPCRs) are important cell surface receptors involved in numerous physiological processes. Although peptides are the cognate ligands for many of these receptors, identifyin...

And a slightly older (but also very exciting!) preprint from the ingenious @lariferg.bsky.social
www.biorxiv.org/content/10.1...

Novel dopaminergic neurotransmission in the Octopus visual system Coleoid cephalopods such as the common octopus have a complex visual system, with a camera-type eye and a large optic lobe, that evolved independently from its counterpart in vertebrates. However, the...

Exiting new preprint from the amazing @amycourtneyyy.bsky.social : www.biorxiv.org/content/10.1...