And here is an interview with Sarah. We reflect on how the culture and structure of cardiology shape the experiences of women in training and practice.
@jaccjournals.bsky.social
www.jacc.org/digital-cont...
Proud moment.
My daughter’s Heartbeats essay at JACC, “Dueling Pursuits: Balancing Motherhood and Medicine,” reflects on pregnancy during med school and the structural barriers women continue to face.
Honest, thoughtful, and important. @jaccjournals.bsky.social
authors.elsevier.com/a/1mdcc_GjkR...
New Health & Veritas bonus episode with Ania Jastreboff, coinciding with the release of Enough: Your Health, Your Weight, and What It’s Like to Be Free (with Oprah Winfrey).
“Having obesity is not a choice. It’s driven by biology.”
@thehowie.bsky.social
🎧 insights.som.yale.edu/podcasts/hea...
“Older adults were, and still are, at the center of cardiovascular care, but they remain on the margins of cardiovascular science.”
My Editor’s Page in the new @JACCJournals issue reflects on why this gap persists, and what must change.
www.jacc.org/doi/10.1016/...
New JACC issue centers on cardiovascular care for older adults:
• Frailty and BP control
• Frailty as a prognostic tool in HF
• Loss of Y chromosome and CV risk
• Vascular cognitive impairment and dementia
Age is not the whole story.
👉 JACC.org @jaccjournals.bsky.social
“The goal isn’t just to live longer, it’s to live better.”
— Ezekiel Emanuel
New Health & Veritas bonus episode 🎙️
insights.som.yale.edu/podcasts/hea...
“If wellness requires constant self-denial, it won’t last.”
— Ezekiel Emanuel
Why eating your ice cream might actually be part of a healthy life.
🎧 Health & Veritas bonus episode
insights.som.yale.edu/podcasts/hea...
“Having friends is better for your immune system and your heart than most people realize.”
— Ezekiel Emanuel
Bonus episode of Health & Veritas 🎙️
🎧 insights.som.yale.edu/podcasts/hea...
“Wellness shouldn’t feel like self-denial.”
— Ezekiel Emanuel
A bonus episode of Health & Veritas on longevity, joy, and what the evidence really says.
🎧 insights.som.yale.edu/podcasts/hea...
🎙️Bonus episode of Health & Veritas
In this special episode, we talk w/Ezekiel Emanuel about his new book Eat Your Ice Cream, why wellness should not feel like punishment, and how evidence can support a life that includes joy. @thehowie.bsky.social
Listen here 👉 insights.som.yale.edu/podcasts/hea...
The Dry January Experiment: What happens to your blood pressure after just one less drink? Evidence from @jaccjournals.bsky.social suggests even light drinking affects your heart health. @yaleschoolofmed.bsky.social @yalesph.bsky.social
👉 neverdelegateunderstanding.substack.com/p/the-dry-ja...
Do clinical trials expire?
New heart attack studies show that evidence from 1980s may not apply to patients in 2025.
Beta blockers are a case study in how medicine evolves, and how slowly our evidence base often keeps up.
My latest Substack:
neverdelegateunderstanding.substack.com/p/do-clinica...
After two years and thousands of manuscripts, I’ve learned that the real work of an editor isn’t gatekeeping — it’s partnership.
My latest JACC Editor’s Page: The Partnership
🔗 www.jacc.org/doi/10.1016/...
#MedTwitter #AcademicMedicine #Cardiology
And be sure to check out our Adipokine Explorer!
www.jacc.org/jacc/interac...
Here is my substack on the topic: Fat, Reframed.
neverdelegateunderstanding.substack.com/p/fat-reframed
@jaccjournals.bsky.social is the place for ideas that may change our thinking; spark dialogue; and contribute to progress in advancing global cardiovascular health.
HFpEF is one of medicine’s biggest puzzles.
Maybe the answers lie not in the heart alone, but in the cross-talk between fat and myocardium.
Read the full JACC Adipokine Spotlight and join the conversation.
🔗 www.jacc.org/toc/jacc/cur...
#JACC #HFpEF #Cardiology #AdipokineHypothesis
The issue invites disagreement and testing.
Some cases of HFpEF may not fit the model.
But frameworks like this push the field forward—helping us ask sharper questions and design better studies.
Themes emerge:
• It’s about fat distribution, not just BMI.
• Adipokines act through endocrine-paracrine signaling.
• Sex, race, and metabolic context all shape expression and risk.
• New therapies (GLP-1RA, SGLT2i) may restore adipokine balance.
To deepen the discussion, we invited experts across cardiology and metabolism to weigh in:
• Erica Spatz: A Turning Point
• Carolyn Lam & Dalane Kitzman: From Pariah to Paradigm
• Subodh Verma & Deepak Bhatt: Parsing the Adipokine Axis
• Faiez Zannad, Jennifer Ho, Robert Mentz, and others.
As Editor-in-Chief, I wrote about why JACC published it:
Because progress in medicine requires ideas that connect disciplines and challenge assumptions.
🧠 “Ideas Worth Testing: The Adipokine Hypothesis.”
www.jacc.org/doi/10.1016/...
In this 25,000-word State-of-the-Art Review, Packer unites >1,800 references to build a testable framework explaining how dysfunctional adipose tissue could underlie HFpEF.
It’s bold, ambitious—and worth debating.
Dr. Milton Packer proposes that hypertrophied, inflamed fat cells secrete molecules—adipokines—that drive cardiac remodeling, inflammation, and fibrosis.
In other words: HFpEF may begin in fat, not the heart.
After decades of disappointment in HFpEF, a new idea is shaking things up.
Could heart failure with preserved EF actually be an adipose-driven disease?
JACC’s latest issue explores “The Adipokine Hypothesis.”
@jaccjournals.bsky.social
🔗 www.jacc.org/toc/jacc/cur...
Physician certification should not be an ordeal; it is in vast need of improvement.
My @jaccjournals.bsky.social Journals Editor’s Page explores how we can modernize physician certification to be relevant, humane, and effective.
🔗 www.jacc.org/doi/10.1016/...
In this Editor’s Page, I outline why we believe authors can use AI tools to improve scientific writing—if they fully own what they submit.
At JACC, we won’t stigmatize responsible use of AI. But we will insist on accountability.
jacc.org/doi/10.1016/...
@jaccjournals.bsky.social
In this Editor’s Page, I outline why we believe authors can use AI tools to improve scientific writing if they fully own what they submit.
At JACC,we won’t stigmatize responsible use of AI. We will insist on accountability.
www.jacc.org/doi/10.1016/...
@jaccjournals.bsky.social @yalemed.bsky.social
For anyone who has wanted a clear, authoritative summary of inflammation and cardiovascular disease, and where the science is heading, here it is.
The 2025 ACC Scientific Statement on Inflammation and Cardiovascular Disease. @jaccjournals.bsky.social www.jacc.org/doi/10.1016/...
This is an extraordinary report from @ihmeuw.bsky.social and published in @jaccjournals.bsky.social; it demonstrates that cardiovascular disease is a global scourge. And we are failing to leverage what we know to save lives. www.jacc.org/doi/10.1016/...
Congratulations to @uvmlarnermed.bsky.social medical student, Sarah Krumholz, for winning the Outstanding Research Publication award for her study in REGARDS investigating risk of hypertension by sRAGE level! Very well deserved!
Her paper: pubmed.ncbi.nlm.nih.gov/40708351/