New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.
The tissue morphogenesis logic, now engineered into living, programmable materials.
www.biorxiv.org/content/10.1...
#ActiveMatter #TissueEngineering
Posts by Alexey Tolchinsky
Thank you. I didn't pull, I was invited. Michael initiated this conversation.
I recall several interesting discussions on "bright lines" in various models. This topic has settled in my mind. Here's what I think:
alexeytolchinsky.substack.com/p/digitize-t...
For those working with cult survivors, complex trauma and DID, this documentary might be useful.
www.youtube.com/watch?v=7iPa...
A conversation with @drmichaellevin.bsky.social, Mark Solms, Karl Friston, and Richard Watson on forgetting, it's adaptive and maladaptive forms. Forgetting is often misunderstood. It essential for us to be able to function and it is a balancing act.
www.youtube.com/watch?v=w_ci...
New discovery! Spoiler alert: Neural dynamics are key.
Evidence for predictive computations in a brain hierarchy during a visual search task
doi.org/10.64898/202...
Work led by @pinotsislab.bsky.social
#neuroscience
New #preprint:
arxiv.org/abs/2604.01932
"BraiNCA: brain-inspired neural cellular automata and applications to morphogenesis and motor control"
@bhartl.bsky.social and Leo Pio-Lopez:
What should the internet look like? Arxiv or wikipedia.
Erik Hoel makes a compelling case for "why sex" as opposed to reproduction via cloning.
substack.com/home/post/p-...
Some planaria reproduce by asexual fission and they are indeed highly resilient, as @drmichaellevin.bsky.social's work shows. Seems that fission eliminates error accumulation.
youtube.com/shorts/FE-ri...
New preprint! Memory in Xenobots.
@paivaibhav.bsky.social , James A. Traer, Megan M. Sperry, Yuxin Zehg
www.biorxiv.org/content/10.6...
Two different experiences produced distinct, long-term, stimulus-specific memories, detectable through both transcriptional and physiological signatures.
A useful computational model of PTSD by @adamlinson.bsky.social and colleagues with a focus on the loss of flexible contextual assessment of danger
www.biorxiv.org/content/bior...
Action potentials are fundamental but there is more going on in brain function.
doi.org/10.3389/fnsy...
#neuroscience
Thank you @chrisfields38.bsky.social
I provide references to specific frameworks in psychiatry and neuroscience where large theoretical buildings were built on an assumption of separability.
#scale
#separability
#context
#quantum
#FEP
#informationtheory
#substrateindependence
We often assume separability in biology, psychology and neuroscience. Sometimes this assumption is justified and sometimes not. Here's a text based on the work of Chris Fields and James Glazebrook illustrating the necessary criterion for separability.
alexeytolchinsky.substack.com/p/context-is...
I realize this thought might sound trivial, but I was hoping to highlight that we extend our mind not only to a calculator or a camera, but also to a fellow human being. Parenting, learning, psychotherapy are prime examples of a small collective - a dyad.
@drmichaellevin.bsky.social's collective intelligence has extended mind idea as component. In a collective, the individual mind is extended onto peers, not tools, and then, because of emergent properties, we have higher, second-order effects of a collective.
Neuroscientist who is great with new media and cares about scientific rigor? DM me. We want to hire someone like you (part time).
including Laurence reminding us that dissociative experiences have been used in religious and spiritual practices for generations.
Thank you also to our wonderful reviewers Ruth Lanius and T. Ryan O'Leary for critique and comments.
Any feedback is welcomed.
Many thanks to Laurence Kirmayer and Ana Gomez-Carrillo, Olivia Norrmén-Smith and everyone who helped organize this meeting, attended, asked very interesting questions and brought up important points
This is a presentation based on our paper with @drmichaellevin.bsky.social, @chrisfields38.bsky.social, Daniel Friedman @activeinference.bsky.social, @lancelotdacosta.bsky.social, David Pincus, Rachael Murphy.
www.frontiersin.org/journals/psy...
A recording of a recent talk at McGill, The Division of Social and Transcultural Psychiatry.
Temporal depth in a coherent self and in depersonalization.
www.youtube.com/watch?v=-8me...
This is not good.
Replies to the comments on
www.sciencedirect.com/science/arti...
is now out here:
www.sciencedirect.com/science/arti...
"From complementarity to non-duality: Seeing objects and processes as pragmatic constructs"
Source
Hoel, E. (2025). A Disproof of Large Language Model Consciousness: The Necessity of Continual Learning for Consciousness. arXiv preprint arXiv:2512.12802.
arxiv.org/pdf/2512.12802
#LLM
#continuous
#learning
#zero-shot
#consciousness