#new_paper: Design, fabrication, and comprehensive investigation for optimal lasing material based on Eu3+ embedded SrO–TeO2–B2O3–P2O5– glass system
@elsevierconnect.bsky.social: optimal lasing material
doi.org/10.1016/j.op...

Near-infrared fluorescent Ag2S quantum dots stabilized by penicillamine enantiomers: influence of ligand chirality on linear and nonlinear optical properties and toxicity We present hydrothermal synthesis and comprehensive physicochemical characterization of water-soluble Ag2S quantum dots (QDs) emitting in the second near-infrared biological window (NIR-II), stabilize...

#new_paper: Near-infrared fluorescent Ag2S quantum dotsstabilized by penicillamine enantiomers: influence
of ligand chirality on linear and nonlinear optical
properties and toxicity
@rsc.org: fluorescent Ag2S
doi.org/10.1039/D5TC...

Ciprofloxacin–polymer conjugates targeted with iron(III) for effective treatment of intracellular bacterial infections The increasing prevalence of multidrug-resistant bacteria necessitates innovative antibiotic strategies beyond the discovery of new active compounds. Here, we report N-(2-hydroxypropyl)methacrylamide ...

#new_paper: Ciprofloxacin–polymer conjugates targeted with iron(III) for effective treatment of intracellular bacterial infection
@rsc.org: Ciprofloxacin–polymer,bacterial infections
doi.org/10.1039/D6BM...

#new_paper: Upconversion Colloid for Tracking Cellular Uptake of Nanoparticles
@mdpiopenaccess.bsky.social: nanoparticles
doi.org/10.3390/ijms...

Dual pH- and thermoresponsive nano-objects with tunable morphologies and dye encapsulation prepared via aqueous emulsion polymerization-induced self-assembly Abstract. Poly(triethylene glycol methyl ether methacrylate)-b-poly[2-(diisopropylamino)ethyl methacrylate] (PTEGMA-b-PDPA) nano-objects, synthesized via p

#new_paper: Dual pH- and thermoresponsive nanoobjects with tunable morphologies and dye encapsulation prepared via aqueous emulsion polymerization-induced selfassembly
@rsc.org: nanoobjects
doi.org/10.1098/rsos...

The graphene oxide evolution: Tailoring molecular architecture for next-gen nanocomposites - Advanced Composites and Hybrid Materials Advanced Composites and Hybrid Materials - The rising demand for lightweight, high-performance materials has intensified interest in graphene-based polymer nanocomposites (GPNCs). Yet, despite...

#new_paper: The graphene oxide evolution: Tailoring
molecular architecture for next-gen nanocomposites
@springernature.com: graphene oxide, nanocomposites
doi.org/10.1007/s421...

#new_paper: The effect of perfluorosulfonic acid membrane molecular structure on excessive swelling in the context of PEM water electrolysis at elevated
temperature and pressure
@elsevierconnect.bsky.social: acid membrane molecular structure
doi.org/10.1016/j.ij...

Building a Simple Platform for Tailoring Peptide Surface Chemistry to Enhance Cellular Uptake of Polymer-Coated Gold Nanoparticles Nanotherapeutic delivery requires particulate systems composed of only a few components yet featuring multiple capabilities to reach the clinic. In this study, we built a platform based on selective reactions (solid-phase peptide synthesis, peptide coupling chemistry, and click chemistry) to enhance cellular uptake of gold nanoparticles (AuNPs) by anchoring cell-penetrating peptides (CPPs) at the outermost layer of the constructs. Model amphipathic peptide (MAP), trans-acting activator of transcription (TAT), hexarginine (R6), and arginine monomer (Arg) were attached to the surface of AuNPs synthesized directly by using branched polyethylenimine (BPEI) polyelectrolyte. From a different perspective, a water-soluble CGSWQWRR sequence capable of promoting the reduction of auric species and steric stabilization of gold colloids was also synthesized. The structure and dynamics of particles were characterized using imaging, scattering, and spectroscopy techniques, and their biological performance was evaluated by assessing cell viability and cellular uptake. The nanoconstructs were noncytotoxic up to 1.0 ppm in the case of CPP–BPEI@AuNPs (5.2 nm metallic core) or up to 10 ppm for CGSWQWRR@AuNPs (30 nm metallic core). Those featuring CPPs at the surface were internalized faster and to a higher extent (∼40% in 4 h) compared to the precursor (∼20% in 4 h). The highest cellular uptake was found for CGSWQWRR@AuNPs (∼75% in 4 h), which mediated the membrane-wrapping process more effectively and was prepared by the easiest protocol (one-pot, two-reactant, no workup reaction in aqueous media). The findings of this study simplify nanoparticle manufacturing, thereby reducing the gap between chemical synthesis and clinical applications.

#new_paper: Building a simple platform for tailoring peptide surface chemistry to enhance cellular uptake of polymer-coated gold nanoparticles
@pubs.acs.org: polymer-coated gold nanoparticles
doi.org/10.1021/acso...

#new_paper: Imidazolium–perfluorophenylborate ion-pair as a high-performance surfactant ionophore
@elsevierconnect.bsky.social: midazolium–perfluorophenylborate
doi.org/10.1016/j.je...

#new_paper: Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation
@elsevierconnect.bsky.social: tumor, nanoparticles
doi.org/10.1016/j.jc...

#new_paper: Effect of amine-terminal dendrimers and dendrimer-based star polymer on Pebax® gas separation membranes
@elsevierconnect.bsky.social: dendrimer-based star polymer
doi.org/10.1016/j.po...

Self-Assembled PEG-Based Fluorosomes for Cellular Internalization Fluorinated amphiphiles are gaining attention in nanomedicine for their unique self-assembly properties and stability, offering opportunities for intracellular drug delivery platforms. We synthesized ...

#new_paper: Self-Assembled PEG-Based Fluorosomes for Cellular Internalization
@acspup1.bsky.social: PEG-Based Fluorosomes
doi.org/10.1021/acsa...

Smart biosensors help detect inflammation early in patients with joint replacements A team led by Elena Tomšík from the Department of Conducting Polymers at the IMC is developing smart biosensors with higher accuracy, smaller dimensions, and broader diagnostic capabilities based on s...

Newly developed smart biosensors by @imcprague.bsky.social will enable faster, more accurate inflammatory markers detection.

“They can reveal inflammation before it fully develops and help precisely identify the causative agent of the infection,” Elena Tomšík says.

www.imc.cas.cz/en/news/smar...

UV-Induced Crosslinking of Poly(tetramethylene itaconate): Toward Sustainable Polymer Networks - Journal of Polymers and the Environment Herein, a novel potential ink for 3D bio-printing, composed of itaconic acid and 1,4-butanediol, was prepared and analyzed. This study investigated the effect of curing time on UV-crosslinked polymer ...

#new_paper: UV-Induced Crosslinking of Poly(tetramethylene itaconate): Toward Sustainable Polymer Networks
@springernature.com: sustainable polymer networks
doi.org/10.1007/s109...

Charge-Shifting Copolymers of 2-(N,N-Dimethylamino)Ethyl Acrylate and 2-Hydroxyethyl Acrylate via RAFT Polymerization: Balancing the Charge Content and Biological Response Synthetic polycations are key components for engineering polyelectrolyte complexes with wide-ranging biomedical potential. However, the high cytotoxicity of fully charged polycations remains a major l...

#new_paper: Charge-Shifting Copolymers of 2‑(N,N‑Dimethylamino)EthylAcrylate and 2‑Hydroxyethyl Acrylate via RAFT Polymerization: Balancing the Charge Content and Biological Response
@pubs.acs.org: copolymers
doi.org/10.1021/acsa...

#new_paper: HPMA polymers as functional excipients in dermal nanoformulations of imiquimod
@elsevierconnect.bsky.social: HPMA polymers
doi.org/10.1016/j.ij...

Nitrogen‐Doped Borane Cluster Network for High‐Performance Supercapacitors Under Universal pH Conditions Nitrogen-doped borane cluster network was prepared as a porous electrode material, featuring 1–2 nm micropores and specific surface area up to 626 m2 g−1. It delivers outstanding supercapacitor perfo...

#new_paper: Nitrogen-Doped Borane Cluster Network for High-Performance Supercapacitors Under Universal pH Conditions
@chemistryeurope.bsky.social: Borane cluster, high-performance supercapacitors
doi.org/10.1002/cssc...

#new_paper: Thermoplastic Starch Composites with Highly Exfoliated Nano-Clay Fillers and Excellent Barrier Properties
@mdpiopenaccess.bsky.social: Starch composites, nano-clay fillers
doi.org/10.3390/ma19...

#new_paper: Surface-engineered porous carbon electrode with polyaniline for high-energy density symmetric and Zn-ion hybrid supercapacitor
@elsevierconnect.bsky.social: carbon electrode, supercapacitor
doi.org/10.1016/j.es...

A Modular Synthetic Strategy toward Fast-Growing Poly(amide-carbosilane) Dendrimers Based on Click Chemistry and Organic Solvent Nanofiltration Dendrimers, constituting a prominent class of monodisperse and multivalent macromolecular compounds with outstanding properties, are characterized by regular and highly branched three-dimensional arch...

#new_paper: A Modular Synthetic Strategy toward Fast-Growing Poly(amidecarbosilane) Dendrimers Based on Click Chemistry and Organic Solvent Nanofiltration
@pubs.acs.org: nanofiltration
doi.org/10.1021/acsp...

Excited-state dynamics of colloidal gold nanoshells functionalized with trimethoxysilylazachalcones In this study, we present a new synthetic approach to obtain trimethoxysilylazachalcones, a family of donor–acceptor chromophores exhibiting strong intramolecular charge-transfer behavior. Their disti...

#new_paper: Excited-state dynamics of colloidal gold
nanoshells functionalized with trimethoxysilylazachalcones
@rsc.org: gold, nanoshells
doi.org/10.1039/D5TC...

Single-Nanoparticle Luminescence Nanothermometers with Enhanced Sensitivity in Physiological Temperature Range In this paper, we presented the unique optical properties of monodispersed and uniform luminescence nanothermometers (LNTs), composed of core (NaYF4:Yb3+,Er3+) and core–shell (NaYF4:Yb3+,Er3+@NaYF4) u...

#new_paper: Single-Nanoparticle Luminescence Nanothermometers with Enhanced Sensitivity in Physiological Temperature Range
@pubs.acs.org: nanothermometers
doi.org/10.1021/acso...

#new_paper: Morphology control in benzoic imine-linked polymer-drug conjugates for adaptive drug delivery and enhanced in vivo efficacy
@elsevierconnect.bsky.social: drug delivery
doi.org/10.1016/j.eu...

#new_paper: Increasing Tc retention during nuclear waste vitrification: Structural and phase change analysis of Al-source behavior by 27Al MAS NMR
@elsevierconnect.bsky.social: nuclear waste vitrification
doi.org/10.1016/j.jn...

#new_paper: Modification of Chitosan with (−)-Gossypol and (−)-Gossypol Acetic Acid Using Free-Radical Grafting Method
@mdpiopenaccess.bsky.social: chitosan, radical grafting method
doi.org/10.3390/ijms...

Structural dependence of the solution behavior of HPMA-based polymers Water-soluble polymers are extensively studied materials in the field of biomedical chemistry research. This study investigates the behavior of methacrylamide-based homopolymers and copolymers with li...

#new_paper: Structural dependence of the solution behavior of HPMA-based polymers
@rsc.org: HPMA-based polymers
doi.org/10.1039/d5py...

Targeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl4-intoxicated mice Carbon tetrachloride (CCl4) metabolism results in the production of highly reactive free radicals and consequent liver tissue damage, making CCl4-induced liver injury an ideal model for studying drug ...

#new_paper: argeted delivery of berberine via ROS-sensitive polymersomes enhances its hepatoprotective activity in CCl4-intoxicated mice
@rsc.org: berberine, intoxicated mice
doi.org/10.1039/D5NA...

#new_paper: Long-term chemical composition of clinker-free hydraulic binder from metakaolin, anhydrite II and lime: 27Al and 29Si MAS NMR, DTA-TG-MS, XRD and SEM investigation
@elsevierconnect.bsky.social: clinker-free hydraulic binder
doi.org/10.1016/j.ri...

#new_paper: Bisphosphonate-Modified Polymer-Coated NaYF4:Yb,Er,Pr Upconverting Nanoparticles for Cell Imaging: Synthesis, Physicochemical Characterization and Biosafety
@wiley.com: polymer coating, nanoparticles, biosafety
doi.org/10.1002/jbmb...

Polymeric Nanocarriers of a Monosubstituted Tetraphenylporphyrin Sensitizer Intended for Photodynamic Therapy and Tumor Imaging To effectively combat advanced cancers, next-generation nanomedicines should combine both therapeutic and diagnostic functions. In this study, we developed stimulus-responsive theranostics systems bas...

#new_paper: Polymeric Nanocarriers of a Monosubstituted Tetraphenylporphyrin Sensitizer Intended for Photodynamic Therapy and Tumor Imaging
@pubs.acs.org: nanocarriers,therapy, tumor
doi.org/10.1021/acso...