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Posts by Zebrafish Rock!

Rock on, @wattlab.bsky.social πŸŽ‰ Congrats! #WomenInScience #zebrafish

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πŸ§ͺ

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For those interested πŸ‘‡ #ZebrafishMeeting

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The plasmids from Karapidaki et al. are on Addgene!
Grab them here:
www.addgene.org/browse/artic...

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Spine-tingling findings from @bertaverd.bsky.social et al. 🀩 πŸ§ͺ #cichild

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Do you know why they are collecting date of birth? 🀨

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Try the free WebApp here: www.mpi-hlr.de/danioheartat... @mpi-hlr.bsky.social 🐟❀️

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Submit your abstracts to be considered for oral presentations during the main sessions or at the Research Interest Group (RIG) mini-sessions 😎 #ZDM19 #ZebrafishMeeting

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Image of a historic building on the campus of Worcester College in Oxford, UK.

Image of a historic building on the campus of Worcester College in Oxford, UK.

Attending #ZDM19? Do consider attending the satellite meeting, Zebrafish Infection and Immunity 9, which takes place at Worcester College the day after #ZDM19 concludes (on 1st October). You will need to submit a separate abstract for #ZII9. More details here: www.zebrafishinfection.co.uk/abstracts

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Logo for the upcoming Zebrafish Disease Models 19 (ZDM19) conference in Oxford, UK. There are two silhouettes of fish that are swimming (one grey and one blue).

Logo for the upcoming Zebrafish Disease Models 19 (ZDM19) conference in Oxford, UK. There are two silhouettes of fish that are swimming (one grey and one blue).

Less than two weeks to go before the abstract deadline for #ZDM19 (Due 1st May) πŸŸβŒ› Don't miss your chance to present in front of the vibrant #ZDMS community! For more details, visit: www.zdmsociety.org/zdm19-abstra...

Please share with your colleagues & labmates 😊 We hope to see everyone in Oxford!

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Do you want to know when your favorite species activates its genome?

Just input its genome size (🧬 in bp) and egg volumen (πŸ₯š in um3) here!

ZGA_onset = -2.37 * log10(gDNA/EggVol) + 11.74

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β€œHere, we generated a comprehensive transcriptomic atlas of early embryogenesis from 61 animal species, spanning 13 phyla. By applying a unified computational framework, we systematically inferred the timing of ZGA across species.”

This is a big one from @mirimiam.bsky.social et al. πŸ”₯πŸ§ͺ

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Maybe πŸ€” It would definitely be cool if the model recapitulates what human hypothyroid disease patients experience!

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Eye growth was not affected by thyroid status. (A) Representative images from sp7:EGFP timeseries illustrating normal growth of the eye in hypoTH fish (orange dashed line), consistent with the observation that eyes are proportionally larger relative to body size in hypoTH fish compared to euTH at multiple stages of development (Hu et al., 2019). (B) Eye diameter increased at a similar rate in euTH and hypoTH fish (n=6 euTH; n=5 hypoTH). (C) Plot of eye diameter relative to standard length showing that the eye grew proportionally faster than the body in hypoTH fish compaed to euTH fish. Scale bar, (A) 1 mm.

Eye growth was not affected by thyroid status. (A) Representative images from sp7:EGFP timeseries illustrating normal growth of the eye in hypoTH fish (orange dashed line), consistent with the observation that eyes are proportionally larger relative to body size in hypoTH fish compared to euTH at multiple stages of development (Hu et al., 2019). (B) Eye diameter increased at a similar rate in euTH and hypoTH fish (n=6 euTH; n=5 hypoTH). (C) Plot of eye diameter relative to standard length showing that the eye grew proportionally faster than the body in hypoTH fish compaed to euTH fish. Scale bar, (A) 1 mm.

Good point πŸ€” The video does appear to show the hypoTH being larger but we think that might be due to lighting/brightness of the screen (i.e. the bone below the eye in hypoTH is very dim). The authors did measure eye size and found no difference between the hypoTH and normal control (euTH). πŸ˜…

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The first half of the video they are at the same scale (Note white bar in bottom right corner). Once it zooms in, the scales are different (note the different sized white bars in the bottom right of each panel) with the hypoTH mutant being much smaller. Hope that helps!

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@itamarh.bsky.social suggests β€œpharmacological cGAS inhibition as a potential strategy for DDR syndromes [during] chronic DNA damage while highlighting that cGAS loss in an otherwise naive background exacerbates pathology & genomic instability, underscoring its essential role in normal physiology.”

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Preview
Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development Thyroid hormone is a key regulator of post-embryonic vertebrate development. Skin is a biomedically important thyroid hormone target organ, but the ce…

Want to learn more? Check out this open-access original research paper on these mutants: www.sciencedirect.com/science/arti... πŸ§ͺ

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Video

Time-lapse of scale development and growth of a thyroid hormone mutant zebrafish (hypoTH), compared to a wild-type control. Credit to Dr. Andrew J. Aman & @dparichy.bsky.social. #ZebrafishZunday πŸ§ͺ

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Confocal micrograph of a mechanosensory neuron with dendrites projecting broadly to cover the entire surface of the tail fin from a 6 day old zebrafish larva. This image is a composite of 5 adjacent high resolution confocal stacks to try and show the entire dendritic morphology of this neuron. Width of image is 1 mm.

Confocal micrograph of a mechanosensory neuron with dendrites projecting broadly to cover the entire surface of the tail fin from a 6 day old zebrafish larva. This image is a composite of 5 adjacent high resolution confocal stacks to try and show the entire dendritic morphology of this neuron. Width of image is 1 mm.

Confocal micrograph of a single sensory neuron in the tail of a #zebrafish larva. Credit to Dr. Kate Turner & @stevewilsonfish.bsky.social. 2017 #NikonSmallWorld Image of Distinction. #ZebrafishZunday πŸ§ͺ

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ICYMI... They join 2025 AACR Fellows, Profs. Leonard Zon & A. Thomas Look 🐟 #zebrafish

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Wonderful news πŸŽ‰ Congrats, @fishjakub.bsky.social! #YouRock #killifish

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Sad day for the #zebrafish community πŸ˜” Our thoughts are with loved ones.

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Always a great #ZebrafishMeeting, for those interested!

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Your procrastination paid off! There’s still time to register 😎 #ZebrafishMeeting

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Support the vibrant #zebrafish community at WUSTL, for those keen 🐟

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New work from @behrenskristen.bsky.social et al 🐠 #cichlid

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New work from Francesca Peri Lab @uzh-ch.bsky.social 🐟 #zebrafish

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Highlights new #zebrafish works from Blueskiers:
@kdrerup.bsky.social: www.biorxiv.org/content/10.1...
@phnglab.bsky.social: www.biorxiv.org/content/10.6...
@roelandmerks.bsky.social: www.biorxiv.org/content/10.6...

Read the full list for more coolness: focalplane.biologists.com/2026/04/17/m... πŸ§ͺ

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❀️

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