This siderophore can be used by another methane-oxidizing bacterium from the same community that doesn't produce it, and provides a molecular link between iron speciation in the environment and methane oxidation

We applied InverSIP to a methane-oxidizing bacterial community to identify an iron-chelating secondary metabolite (siderophore) used by methane-oxidizing bacteria to acquire insoluble ferric iron from their environment

We combined stable isotope probing with the inverse labeling method we have been using to link biosynthetic genes to their products in a method we call InverSIP

Inverse stable isotope probing–metabolomics (InverSIP) identifies an iron acquisition system in a methane-oxidizing bacterial community | PNAS Methane is a potent greenhouse gas and a target for near-term climate change mitigation. In many natural ecosystems, methane is sequestered by micr...

Excited to announce this is now published!
www.pnas.org/doi/10.1073/...

It has been great fun to work with Aaron Puri's team @awpuri.bsky.social on this project. InverSIP is a clever tool for linking genotype and phenotype.

Inverse stable isotope probing–metabolomics (InverSIP) identifies an iron acquisition system in a methane-oxidizing... www.pnas.org/doi/10.1073/...

Proud to announce “RefAHL,” an updated, curated collection of LuxI-type quorum sensing signal synthases with their products and associated metadata. RefAHL is publicly available to help catalog LuxI-type diversity encoded in (meta) genomic data.

journals.asm.org/doi/10.1128/...