Little Lab, UCSF Neurology

Grateful to the big team and collaborators including Jeffrey Herron, Ph.D. and @gallantlab.org who helped make this possible as well as other members of littlelab.ucsf.edu

This was fully programmed using ML, remotely in patients own homes, addressing the challenges of increasing DBS programming complexity.

Movement-responsive deep brain stimulation for Parkinson’s disease using a remotely optimized neural decoder - Nature Biomedical Engineering An adaptive deep brain stimulation algorithm delivers targeted stimulation increases during movement using brain motor signals.

Happy to share our latest study led by Tanner Dixon and our team @ucsfhealth.bsky.social and @neurosurgucsf.bsky.social out today in Nature BME! Movement Responsive, AI programmed, BCI-aDBS improves naturalistic movements and reduces excessive movements at rest in PD.
www.nature.com/articles/s41...

I'd like to see a revival of panache and artistry in scientific prose style. Since we have to read so many papers, they should be fun and beautiful. I would also argue that this serves the goal of communication: readers will be more likely to remember a striking phrase or image.

Happy to be launching this Special Edition in NPJ Parkinson’s on all things sleep and PD related

Psilocybin desynchronizes the human brain - Nature Healthy adults were tracked before, during and after high doses of psilocybin and methylphenidate to assess how psychedelics can change human brain networks, and psilocybin was found to massively disr...

Nature

Psilocybin desynchronizes the human brain
www.nature.com/articles/s41...

This will build on amazing recent work by @melgaby.bsky.social and others, looking at how planning algorithms are encoded in prefrontal cortex circuits: bsky.app/profile/melg...

Great job Andy!!

Jimmy- you are the best and thoroughly deserved!!!

This is figure 6, which shows that DBSLH mediates long-term improvements in walking in humans with SCI.

A study in Nature Medicine finds that deep brain stimulation of a region called the lateral hypothalamus improves walking and promotes recovery in humans and rodents with spinal cord injury. https://go.nature.com/3Vlosyl 🧪