*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!
Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃)
Find the paper here: www.nature.com/articles/s41...
At #cosyne2026? Check out Sumedha Nalluru’s poster from our lab! Showing that reduced cortical inhibition causes false associations. Friday 13th March from 1:15 - 4:15pm.
Interested in cognitive maps? Wondering how you should best train your participants? Luckily for you, we have investigated just that! Very excited to share a preprint from my PhD in which we show how initial training curriculum affects the cognitive maps we form
osf.io/preprints/ps...
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Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization:
doi.org/10.1117/1.NP...
🎉 My PhD work has just been published in @natcomms.nature.com!
How do we learn who caused what - and how much control we had - when outcomes depend on multiple people? We studied how humans do so using a new social learning task, computational modelling and fMRI.
www.nature.com/articles/s41...
🧵👇
1/ Excited to share that our symposium review covering cognitive mapping in the PFC just came out in the Journal of Neuroscience: www.jneurosci.org/content/45/4...
** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet **
Deadline: 2nd December
1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6
2. TUS and TMR in humans:
tinyurl.com/jjws5ctj
Happy to chat to interested applicants.
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
Energy of novel and familiar stimuli
New unit paper on “Predictive coding model detects novelty on different levels of representation hierarchy”, published in Neural Computation.
www.mrcbndu.ox.ac.uk/papers/predi...
@mrcbndu.ox.ac.uk @ndcnoxford.bsky.social @ox.ac.uk
I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social !
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.
(1/13)
Our study using layer fMRI to study the direction of communication between the hippocampus and cortex during perceptual predictions is finally out in Science Advances! Predicted-but-omitted shapes are represented in CA2/3 and correlate specifically with deep layers of PHC, suggesting feedback. 🧠🟦
Happy to share the latest version of our work on compositional maps in hippocampus with Jo Warren, @jcrwhittington.bsky.social, @behrenstimb.bsky.social. We propose hippocampus constructs maps from cortical building blocks in replay – now with empirical support! www.nature.com/articles/s41... 1/9
New preprint out with @summerfieldlab.bsky.social! When does new learning interfere with existing knowledge? We compare continual learning in humans and artificial neural networks, revealing similar patterns of transfer & catastrophic interference (1/8) osf.io/preprints/ps...
We are currently building the largest, cross-domain data set of human behavior as part of an open collaborative project. Contributions of any form are welcome, but especially experiments with meta-data from developmental, cross-cultural, or clinical studies.
More details: github.com/marcelbinz/P...
Many thanks to the reviewers for their useful comments and feedback.
We show that memory reactivation during awake rest plays a critical role in extracting new, unobserved associations to support adaptive behavioural strategies such as inference. 6/6
TMR improved discovery of new, non-directly trained associations, and no change was observed for directly trained associations. 5/6
We demonstrate that TMR during awake rest enhances performance on associative memory tests. 4/6
We investigated this using a pre-registered, within-subject human study design with a rich behavioural paradigm. We used contextual Targeted Memory Reactivation (TMR) to causally manipulate memory reactivation during awake rest. 3/6
Periods of rest and sleep are reported to facilitate adaptive behaviours, such as our ability to make inferences, perform abstraction and acquire insight. However, the mechanism by which these adaptive behaviours emerge remains unclear. 2/6
Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out www.nature.com/articles/s41...! With Annie Rawson, Jill O’Reilly and Helen Barron at MRC BNDU @ndcnoxford.bsky.social 1/6
