I was investigating the genomes that I didn't manage to convert to near-complete MAGs in my assembly graph (the components in gray).
The circle on top left is actually a complete genome but with 40% completeness (both in metaMDBG and myloasm)
Posts by Loïs Maignien, PhD.
GTDB release 11 based on RefSeq 232 (R11-RS232) is live at gtdb.ecogenomic.org. This release covers 901,341 genomes (23% increase) and has 199,923 species clusters (39% increase). Release notes at: forum.gtdb.ecogenomic.org/t/announcing.... Release statistics at: gtdb.ecogenomic.org/stats/r232.
In my latest column, I explain some of my reasons for being deeply skeptical about AI models that claim to understand DNA, genes, and genomes: stevensalzberg.substack.com/p/ai-is-star...
Researchers Uncover Hidden Genetic World in Antarctic Waters
"at least a third of the genes identified are missing from existing marine gene catalogs"
@loimai.bsky.social #microbiome #oceans
Exciting new methane research: Huge credit to @annajwallenius.bsky.social & Andy Leu for using nifty bioinformatics to disentangle 8 novel MAGs of 'Candidatus Methanoborealis' This is version 1 of our #bioRxiv preprint. Aanalysis is ongoing & we welcome your feedback!
doi.org/10.64898/202...
Living patescibacterial (CPR) cells are a rare sight! Meet Strigamonas methylophilicida, a parasite of methylotrophic proteobacteria we just described in our latest paper:
doi.org/10.1128/mbio...
a figure from the linked paper which shows A) a world map and B) a schematic representation of various natural and artificial habitats, both annotated with information about which sulfur disproportionating bacteria have been found in the specific regions and environments
New paper from my 2nd PostDoc is now published in The ISME Journal by @isme-microbes.bsky.social!
#Sulfur disproportionation occurs globally across anoxic habitats & has multiple mechanisms of independent evolutionary origin academic.oup.com/ismej/advanc...
#Bacteria #Microbes #Evolution #DeepSea
I'm thankful to MBE for publishing this paper. I wan't sure anybody would. The handling editor (I now know was Jeff Townsend) was great, as were the 2 reviewers. It is not an outcome/product/discovery, it is my way of thinking about HGT & pangenomes 1/3 academic.oup.com/mbe/article/...
Hello Ian, linking 'omics observations to ocean biogeochem is our grand challenge for all of us... Not there yet, but several smart ideas worth following: www.science.org/doi/full/10.... or www.primoscorwg.org Happy to talk more about the article data implications...
Since you arrived here, I want to share this: this article is a gem to me because this project could have failed at so many crossroads. Only with the contribution and trust of brilliant authors and friends could this happen! That what it takes ...10/10
Finally, this work brings a wealth of genomic data (218 metagenomes) associated with 50 environmental variables that will help putting the Southern Ocean at the center of the map… Code and data in the paper! More to come from visionary research programs like this one www.antarctica-insync.org 7/n
DMSP lyase is one of the plankton functions that is most linked to environmental variations, suggesting a central role of sulfur compounds in this polar environment... 8/n
This microscopic world is structured by water mass, illustrating how ocean circulation controls marine life. Some ubiquitous bacteria (SAR11) adapt their genetic repertoires to thrive in all latitudes. 7/n
After a long bioinformatics journey, we found that about 1/3 of the plankton genes were never observed in any other ocean: this biome is unique! …6/n
To fill this important gap, we embarked on a fantastic Antarctic Circumnavigation Expedition to sample the different regions of the Southern Ocean and study plankton DNA. Take a deep dive in the Roaring Forties and the Furious Fifties with us: www.youtube.com/watch?v=lZkt... …5/n
Due to low accessibility, we miss data and observations to understand and predict its evolution. Until recently, an extensive plankton genomic diversity survey of this ocean was still missing from global ocean data rdcu.be/e7Nep ...4/n
It is a fragile ecosystem with unique diversity of life and ecosystems and is the cradle of deep-water masses that feed the world’s Oceans. Now, the Southern Ocean seems to undergo abrupt changes, mostly visible in the last decade from strong sea ice cover anomalies. rdcu.be/e7M9R ... 3/n
It is rarely seen on a world map. Yet, the Southern Ocean is central for the functioning of our planet! It absorbs CO2 and heat like no other with respect to its surface. Let’s take a different view: rdcu.be/e7Nbh ... 2/n
Very happy to share the latest paper of our group (et al.)! rdcu.be/e7zyX . This one has a special place… 1/n
Interested in developing your skills in microbial 'omics? Consider joining us in Brest 🇫🇷, Oct. 10-24 for two weeks of intensive lectures an tutorial from top faculties and TA! maignienlab.gitlab.io/ebame/
Bonus: beautiful seascape and friendly spirit!
Antarctica InSync will host two webinars, bringing together the science community to discuss the draft White Papers currently available on our website.
· 20 January, 17:00–19:00 (CET)
· 21 January, 09:00–11:00 (CET)
📌 Register: lnkd.in/epX4_JiA
📝 Provide input to the draft papers: lnkd.in/eYfJgTUV
Now published in Nature Biotechnology:
go.nature.com/44P7nSm
If you missed it, the TL;DR is in my April thread below
1/ The overturning circulation is a network of ocean currents transporting heat, carbon, oxygen and nutrients around the world. At the heart of this circulatory system is the global pumphouse of #Antarctica and the Southern Ocean.
Animation: NASA-SVS
I'm proud to share the latest methods work from my group. Led by @revathykri.bsky.social we wrote a book chapter on how we process and analyse viromes.
Thanks to co-authors @rikhaagmans.bsky.social @ryancook94.bsky.social & Alise Ponsero
link.springer.com/protocol/10....
www.nature.com/articles/s41...
Thrilled to share our new study! We show that mirusviruses include lineages packed with spliceosomal introns and likely replicating in the nucleus of unicellular eukaryotes—a sharp contrast to most large and giant eukaryotic viruses that replicate in the cytoplasm.
Come join us! Soon I will be advertising a postdoc vacancy in my group as part of my @erc.europa.eu AdG project 'DARK ROOTS'. Focus of the project will be on phylo- and metagenomic mining of novel prokaryotic lineages. I will soon post a link here - stay tuned, and please repost! #asgardarchaea
I am very excited to announce that a fully funded PhD position is available in my group.
Topic: Synergistic coevolution in mono-specific and multi-species microbial consortia
Please RT or forward this information to interested candidates.
Deadline: 11.01.26
More info:
shorturl.at/f1TuF
New GEOTRACES Science Highlight! 🌊
Long-range transport of iron via the #Agulhas Current and counter-current: a boon for the phytoplankton
www.geotraces.org/long-range-t...
Paper first authors: Eva Bucciarelli & Pierrick Penven, LEMAR
#oceanscience #traceelements
@scor-int.bsky.social