Endocrine Connections logo. New Research by CJ de Gans et al. PDF of https://doi.org/10.1530/EC-26-0014.
A new study by C J de Gans examined estradiol levels and sleep in 4,754 men and women.
Overall, estradiol was not clearly linked to sleep quality or timing, though those in the highest 10% reported slightly better sleep.
🔗Read the full study: doi.org/10.1530/EC-2...
Endocrine Connections logo. Reproductive Endocrinology logo. From patients to partners: evaluating a co-designed website for congenital hypogonadotropic hypogonadism By Andrew A Dwyer et al. https://doi.org/10.1530/EC-26-0027 Published by Bioscientifica logo. Society for Endocrinology logo. European Society of Endocrinology logo.
New research by Andrew A. Dwyer et al. evaluates a co-designed website for congenital hypogonadotropic hypogonadism.
Patients were involved at every stage, the site scored >88% on quality, and 95% would recommend it.
Part of Reproductive Endocrinology 2025.
🔗 Read here: doi.org/10.1530/EC-2...
Endocrine Connections logo. New Review. The complex interaction between obesity and puberty and its implications for pubertal timing: a review of recent evidence. By Kettyuscia Coelho e Oliveira et al. Graphical Abstract: Endocrine Connections 15, 3; 10.1530/EC-26-0069 Published by Bioscientifica logo. Society for Endocrinology logo. European Society of Endocrinology logo.
New review by Kettyuscia Coelho e Oliveira et al.: Childhood obesity may influence puberty timing in boys and girls through hormones like leptin and insulin, as well as gut microbiota.
🔗 Read the full review here: doi.org/10.1530/EC-2...
Endocrine Connections logo. Endocrine Connections journal cover. Cortisol-to-cortisone ratio postpartum is associated with anti-Müllerian hormone a decade later: evidence from a prospective study. By Gary Joseph et al. https://doi.org/10.1530/EC-25-0871. Published by Bioscientifica logo. Society for Endocrinology logo. European Society of Endocrinology logo.
How does postpartum stress impact long-term reproductive health?
New research by Gary Joseph et al. finds that a higher cortisol-to-cortisone ratio after childbirth is linked to lower AMH levels - even 10 years later.
🔗 Read the full article: doi.org/10.1530/EC-2...
Endocrine Connections logo. SAVE THE DATE. Endo-ERN Vol II: Rare Diseases and Transition in Care. Special Collection - Dedicated Webinar. Endo-ERN X Endocrine Connections Genetic Testing Approaches as the Basis for Personalized Medicine. Wednesday 10 June 2026. 16:00-17:00.
Register now for the first webinar in our new series supporting the Endo-ERN Vol II: Rare Diseases and Transition in Care collection.
Endo-ERN x Endocrine Connections: Genetic Testing Approaches as the Basis for Personalized Medicine
📅 10 June 2026 | 16:00–17:00
endo-ern.eu/event/placeh...
Endocrine Connections logo. Award icon. Q1 Editor's Choice Award. Elexacaftor–tezacaftor–ivacaftor enhances first-phase insulin secretion and improves glucose control in cystic fibrosis. By Anna Edlund et al. Paper picked by: Deputy Editor, Professor Henrik Oster. Editor-in-Chief, Professor Faisal Ahmed.
We’re proud to announce that our Q1 Editor's Choice Award goes to the article: “Elexacaftor–tezacaftor–ivacaftor enhances first-phase insulin secretion and improves glucose control in cystic fibrosis”.
🎉💙 Congratulations to the authors!
Read the full article: doi.org/10.1530/EC-25-0690
Endocrine Connections logo. Cushing's Awareness Day. 3 PDFs of published articles: Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome / Patients with Cushing’s syndrome suffer from provoked venous thromboembolism and are anticoagulated in various patterns / High recovery rate of adrenal function after successful surgical treatment of Cushing’s syndrome
April 8th is Cushing's Awareness Day 💛💙
Today we’re highlighting 3 studies exploring:
- Cardiac remodelling in ACTH-dependent disease: doi.org/10.1530/EC-2...
- Venous thromboembolism risk in patients: doi.org/10.1530/EC-2...
- Recovery of adrenal function after surgery: doi.org/10.1530/EC-2...
Endocrine Connections logo. SPECIAL COLLECTION. Pearls and Pitfalls in Adrenal Malignancies New Article Published.
"Adrenal tumour diagnostic pathway: findings from a UK national survey” by Sherwin Criseno et al., the 2nd article published in: Pearls and Pitfalls in Adrenal Malignancies.
The survey highlights guideline adherence and variability in multidisciplinary practice.
🔗 doi.org/10.1530/EC-2...
🌙 First article in our Endocrine Rhythms collection is live!
C.J. de Gans et al. explore how estradiol levels relate to sleep in 4,754 adults - minor links in the highest levels, but key insights for understanding hormonal cycles.
Read here: doi.org/10.1530/EC-2...
📢Applications are open for Editor(s)-in-Chief of Endocrine Connections (co-Editor-in-Chief pairs welcome). Lead the journal’s strategy, peer review and global growth.
⏱️Deadline: 31 May 2026
🔗For more info: ec.bioscientifica.com/page/EIC-vac...
@esendocrinology.bsky.social Member Paper Highlight:
Discontinuing rhGH at mid-puberty in adolescents with GHD did not reduce patient-reported QoL, while parents reported slightly higher well-being.
Congrats to Joeri Vliegenthart et al.!
🔗 doi.org/10.1530/EC-2...
We are pleased to announce the launch of our latest special collection: Barocrinology: The Science of Obesity Medicine.
Obesity is an endocrine disease. This collection covers causes, phenotypes, diagnosis & treatment.
Now open for submissions!
Learn more: ec.bioscientifica.com/page/barocri...
Are we underestimating hyperglycemia during chemotherapy?
New research by Lukas van Baal et al. shows real-time CGM detects far more cases of steroid-induced hyperglycemia than conventional monitoring, highlighting a gap in current clinical practice.
Read here: doi.org/10.1530/EC-2...
Could burosumab provide sustained benefits for adults with tumor-induced osteomalacia (TIO)?
A new Phase 4 study by Ruizhi Jiajue et al. reports improved serum phosphorus, mobility, and quality of life with a favourable safety profile in Chinese patients.
Read here: doi.org/10.1530/EC-2...
Research by P. B. Edström et al. establishes sex- and age-specific reference intervals for ACTH & renin in 529 healthy youths, with insights into puberty & contraceptive use.
The results provide standardised SD scores to support monitoring of pediatric endocrine disorders.
doi.org/10.1530/EC-2...
A new study by Elena Chertok Shacham et al. finds that adjusted ethnic differences in #dementia risk among older adults with type 2 diabetes were attenuated, while SGLT-2 and DPP-4 inhibitors were associated with lower dementia risk and mortality.
Read here: doi.org/10.1530/EC-2...
Congratulations to Dr. Sandra Pereira, recipient of the 2026 Endocrine Connections Expert Reviewer Prize 🏆
Recognising exceptional commitment to high-quality peer review and research excellence at Endocrine Connections.
Thank you for your dedication to the endocrine research community!
The 1st article in Pearls and Pitfalls in Adrenal Malignancies, is now live:
Yanagida et al. demonstrate that CT attenuation values are highly reliable (even when measured by non-radiologists) and remain a robust tool for excluding adrenal malignancy and pheochromocytoma.
doi.org/10.1530/EC-2...
A randomised controlled study by Yifan Liu et al. shows that 6 weeks of vitamin D in gestational diabetes improved oxidative stress and inflammation and was linked to lower neonatal birth weight and reduced macrosomia, with no significant change in fasting glucose.
🔗 doi.org/10.1530/EC-2...
A new case report by Lucia Digitale Selvaggio et al. links RTN4IP1 mutations with endocrine failure, expanding the known phenotype of this mitochondrial disorder. The study also considers the potential therapeutic role of coenzyme Q10.
Explore the full article: doi.org/10.1530/EC-2...
Today #FEBRURAY11 we celebrate the contributions of women and girls advancing research and innovation in our field and across global scientific community.
Endocrine Connections remain committed to supporting inclusive, equitable research environments - in science and in publishing.
#IDWGS
New review by Michel Kabbash et al.: evidence suggests skeletal muscle is a direct target of excess PTH in primary hyperparathyroidism - affecting strength, gait, and physical function, with potential reversibility after surgery.
Read the full article here: doi.org/10.1530/EC-2...
New research by Yasmine Alshammari et al. shows plasma EGF is lower in type 2 diabetes and correlates with fasting glucose, HbA1C, TG & waist-to-hip ratio, highlighting its potential as a biomarker for glycaemic control.
Read the full article here: doi.org/10.1530/EC-2...
Postprandial GIP levels are inversely associated with active (HMW) adiponectin in normoglycemic women.
This study by Isidora Salvatierra et al. suggests GIP may serve as an early biomarker of metabolic disturbances linked to increased adiposity, before obesity develops.
🔗 doi.org/10.1530/EC-2...
New research by Kristina Laugesen et al. shows that the Elecsys Cortisol II assay closely matches LC-MS/MS and that baseline cortisol cutoffs can be used as a fast, reliable way to screen for adrenal insufficiency.
Read the full article here: doi.org/10.1530/EC-2...
New research by Bailly et al. shows that continued growth hormone therapy after final height may improve lumbar spine bone density in patients with persistent childhood-onset GHD.
Read here: doi.org/10.1530/EC-2...
Explore the special collection: ec.bioscientifica.com/page/bone-an...
We’re pleased to announce the first 2026 Special Collection in Endocrine Connections: Pearls and Pitfalls in Adrenal Malignancies.
For more information, visit: ec.bioscientifica.com/page/adrenal...
New research from Society for Endocrinology member, Rajeev Mehta et al. shows that symptom-led tapering of physiological glucocorticoid doses promotes safe adrenal recovery, challenging current guidelines.
Read the full article here: doi.org/10.1530/EC-2...
Cystic fibrosis–related diabetes affects many patients with CF. A new study by Anna Edlund et al. finds that ETI therapy enhances insulin secretion and normalises glucagon levels, offering hope for improved glucose management in this population.
Read the full article here: doi.org/10.1530/EC-2...
Thyroid overactivity worsens patients' quality of life (QoL). After treatment, QoL is not completely restored for many patients. We discuss reasons, and new approaches to address long-term effects on QoL.
@ncaresearchnhs.bsky.social
@endoconnect.bsky.social
www.researchgate.net/publication/...