👉 Register: epicentre.msf.org/journees-sci...
We'll let you know as soon as the full program is online

Looking back at our Scientific Day! YouTube video by Epicentre - MSF

Still undecided about Epicentre’s Scientific Day on 4 June?
Hear from participants of the 2025 edition
A unique opportunity to discover our research and see how it translates into concrete action in MSF operations, as well as its contribution to international guidelines.
youtu.be/Ernl2JCQCPo?...

👉 Register: epicentre.msf.org/journees-sci...
We'll let you know as soon as the full program is online

A strong illustration of the importance of highly collaborative efforts and multicountry solutions to cholera control. Coordinated genomic surveillance can uncover cross border transmission and critical shifts in the bacterial genome.
www.nature.com/articles/s41...

Tuberculosis: Documenting the transition to shorter treatments for multidrug-resistant TB under real-life conditions In Pakistan, Epicentre is conducting a study to better understand how new, all oral, shorter treatments for multidrug-resistant/rifampicin‑resistant tuberculosis (MDR/RR-TB) are implemented in real-world settings. These treatment regimens have already proven effectiveness in clinical trials, and are recommended by the World Health Organisation (WHO), but what about once they leave the controlled setting of a trial? The study explores their impact on patients' lives, their feasibility for healthcare providers, and their acceptability in a context where challenges remain numerous: treating children and pregnant women, managing highly resistant forms of TB, and monitoring the emergence of new resistance.

New shorter, all oral MDR/RR TB regimens work in trials, but how do they work in real life?
A study in Pakistan looks at feasibility, acceptability and impact of MDR/RR TB treatments beyond controlled settings, including for children and pregnant women.
epicentre.msf.org/en/news/tube...

Most HIV programmes kept ART initiations stable during the 1st year of COVID 19 — a sign of resilience. But declines in some settings show the need to understand what sustained ART under strict measures so we can be better prepared.
bmjopen.bmj.com/content/16/3...

Pediatric TB (r)evolution(s) YouTube video by MSF Access

Why half of the 1.2 million children with TB cannot access diagnosis and lifesaving treatment? Watch this video to learn more. #WorldTBDay
www.youtube.com/watch?v=6k6Y...

Enquêtes de mortalité : un outil essentiel en contexte humanitaire YouTube video by Epicentre - MSF

🔍 Mortality surveys: a key tool in humanitarian aid
Dr. Gaston Komanda explains how these surveys can be used to measure the impact of crises on populations, guide humanitarian interventions, and advocate for change.
📺 Watch here 👉 youtu.be/7oxMH13Or7s?...

Learn R for Humanitarian Epidemiology
· An open source platform
· Available in English & French
Perfect for self‑learning, trainings & field support
Boost your analytical skills in real‑world humanitarian settings.
👉 Access the platform: epicentre-msf.github.io/repicentre/

Congratulations @dndi.org on this major milestone! A powerful step forward in the fight against sleeping sickness.

Community and hospital-acquired invasive bacterial infections in hospitalised patients with advanced HIV disease: a prospective study in Kinshasa, DRC Advanced HIV patients face high mortality, often from invasive bacterial infections (IBI), while rising antimicrobial resistance (AMR) threatens treat…

Hospitalised patients with advanced HIV in Kinshasa faced frequent invasive bacterial infections, with different pathogens driving community‑ vs hospital‑acquired cases.
⚠️ High ceftriaxone resistanceand emerging carbapenem resistance raise major concern.
www.sciencedirect.com/science/arti...

📢 HIV clinics in Burkina Faso, Côte d’Ivoire & Nigeria largely maintained ART access during the pandemic — but viral load monitoring was heavily disrupted and didn’t return to pre‑COVID levels a year later. 👇 journals.lww.com/jaids/fullte...

Pediatric cancer Discover Epicentre's current studies on pediatric cancers

World Childhood Cancer Day
In Uganda, 3,000 children develop cancer each year, but only 1,000 are diagnosed, often too late.
With the MUST, we're working to change this.
🎯 Goal: A locally adapted early diagnosis algorithm to improve care.
👉 epicentre.msf.org/en/our-proje...

Low-dose yellow fever vaccination in infants: a randomised, double-blind, non-inferiority trial Compared with the standard yellow fever vaccine dose, a dose of 500 IU did not meet the non-inferiority criterion, suggesting that minimum dose requirements in adults are not generalisable to infants....

Yellow fever & minimum vaccine doses
500 IU works in adults — non inferior to the standard dose.
👶 In infants, it’s different: a Kenya/Uganda study shows 500 IU fails non inferiority.
👉 Adult thresholds ≠ infant thresholds.
www.thelancet.com/journals/lan...

Diagnostic Performance and Kinetics of Hepatitis E Viral RNA and IgM Antibody Test Positivity in a Genotype 1 Outbreak in South Sudan The assure IgM RDT showed higher sensitivity for identifying hepatitis E than PCR and similar specificity to IgM ELISA, supporting its use in surveillance.

Using surveillance data from MSF’s Bentiu vaccine study, we evaluated the performance of the tests. The Assure RDT showed good sensitivity (86%), outperforming PCR and specificity comparable to ELISA (94.7%).
✅ Supports its use in Hep E surveillance academic.oup.com/jid/article/...

Session | Cancer YouTube video by Epicentre - MSF

📢 Cancer: A growing challenge across African countries
On #WorldCancerDay, explore our work on breast and cervical cancer in Mali and Malawi, as well as childhood cancer in Uganda
youtu.be/537grgfZU3s

Trends in Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine and amodiaquine over ten years of seasonal malaria chemoprevention in Moissala Health District, Chad - Malaria Journal Background Seasonal Malaria Chemoprevention (SMC) has been implemented in Moissala Health District, southern Chad, since 2013 using the standard regimen of sulfadoxine-pyrimethamine (SP) and amodiaqui...

In @malariajournal.bsky.social we report that after ten years of molecular surveillance in Chad, SP-AQ used for seasonal malaria chemoprevention remain largely effective, though rising markers of partial resistance underscore the need for ongoing monitoring.
link.springer.com/article/10.1...

🗓️ Save the Date!
The next Epicentre Scientific Day will take place on 4 June 2026 at the Palais de la Femme in Paris and online.
A special edition celebrating Epicentre’s 40th anniversary 🎉
Programme coming soon — but you can already register here. 👇
epicentre.msf.org/journees-sci...

fragile and conflict-affected settings: post-abortion care generally satisfactory, but communication needs to be improved The AMoCo* study continues to highlight persistent challenges related to abortion care and complications in fragile and conflict-affected settings. Conducted in two hospitals in Bangui (Central Africa...

Fragile and conflict affected settings: New AMoCo findings show post abortion care is mostly satisfactory, but communication, respect and confidentiality remain major gaps—especially for adolescents and women with less education.
@itmantwerp.bsky.social
epicentre.msf.org/en/news/frag...

Health-economic impacts of age-targeted and sex-targeted Lassa fever vaccination in endemic regions of Nigeria, Guinea, Liberia, and Sierra Leone: a modelling study Lassa fever is an emerging zoonotic disease endemic to west Africa. Several vaccines aimed at preventing Lassa fever are currently under development, …

Lassa fever vaccination strategies
A new vaccine‑impact modelling study shows that targeting adolescents and adults could deliver the greatest health‑economic value per dose
👉 though the most cost‑effective strategy will depend on vaccine price.
www.sciencedirect.com/science/arti...

In Koutiala, Mali, 41% of <5 children referred from community to reference health centers never completed the referral
Main barriers: transport, distance, perceived costs, lack of follow-up.
▶️Strengthening referral systems is critical for timely care.
link.springer.com/article/10.1...

Not forgetting the humanitarian contexts in the fight against antimicrobial resistance: Operational-driven reflection on knowledge and research gaps by Médecins Sans Frontières Despite Antimicrobial Resistance (AMR) being a growing threat to global public health, there is scarce evidence from humanitarian settings. Working in fragile contexts, Médecins Sans Frontières (MSF) ...

📖 Must-read: AMR in Humanitarian Settings
AMR is a global health threat, yet evidence from fragile contexts is scarce.
MSF’s review highlights research priorities for the most vulnerable:
✅ IPC
✅ AMS
✅ Diagnostics & Surveillance
journals.plos.org/globalpublic...

Euvichol-S: documenting the operational effectiveness of this new oral cholera vaccine With cholera epidemics on the rise and global vaccine stocks remaining under pressure, in 2024 the WHO prequalified a new oral cholera vaccine, Euvichol-S, designed to respond more quickly to demand. ...

As cholera outbreaks surge and global vaccine supplies remain strained, WHO prequalified Euvichol-S in 2024 to meet demand faster.
➡️ For the first time, a study assesses its real-world effectiveness in a one-dose regimen during an epidemic in South Sudan.
epicentre.msf.org/en/news/euvi...

Analyzing the acceptance, adoption and impact of new HIV prevention tools: a study among sex workers in Malawi Since 2022, the World Health Organization (WHO) has recommended long-acting injectable cabotegravir (CAB-LA) as an innovative method of pre-exposure prophylaxis (PrEP) against HIV. Epicentre in partne...

How can HIV prevention be made more accessible to the populations most at risk?
In Malawi, Epicentre and MSF are conducting a study to document the introduction of CAB-LA among sex workers, a group particularly at risk of HIV infection.
#VIH #PrEP
epicentre.msf.org/en/news/anal...

Responsable des Activités Epidémiologiques (H/F), CDD 12 mois, basé (e) à N'Djaména - Tchad Description de l'entreprise: Créée par Médecins Sans Frontières (MSF) en 1986, Epicentre mène des activités d’épidémiologie de terrain, de formation et de recherche médicale en appui aux objectifs hum...

On recrute un.e responsable des activités épidémiologiques pour la mission Tchad de MSF France. Vous avez un diplôme en épidémiologie ou en santé publique, postulez ci-dessous 👇🏾
smrtr.io/vWCQ3

Diagnostic Accuracy of Lung Ultrasound for Pulmonary Tuberculosis in out-patients from Papua New Guinea, a Resource-Limited setting to evaluate the diagnostic accuracy of lung ultrasound (LUS) for pulmonary tuberculosis (PTB) in Papua New Guinea.Prospective observational study incl…

Lung ultrasound (LUS) shows promise in TB diagnosis
➡️High sensitivity, comparable to chest X-ray, but lower specificity
✅Valuable where radiography is unavailable
✅a new scoring system developed improves accuracy, but further validation is needed
www.sciencedirect.com/science/arti...

Session | Diagnostics for Antibiotic Stewardship YouTube video by Epicentre - MSF

🌍#WorldAMRWeek
Replay our Scientific Day session on Diagnostics for Antibiotic Stewardship:
✔ Avoid inappropriate STI treatments
✔ Why cumulative antibiograms matter
✔ Rapid tests for carbapenemase-producing bacteria in MSF labs
🎥 Watch now: youtu.be/FlwmAVONDuo

World Children’s Day 2025 YouTube video by IMVACS Project

How can we better protect children from malaria in highly seasonal regions?
Epicentre is pleased to be part of the Imvacs Project testing an integrated approach: combining the R21/Matrix-M vaccine with Seasonal Malaria Chemoprevention for children in Mali & Burkina Faso.
youtu.be/r2v9EvWQ1JE?...

WHO treatment decision algorithms double pediatric TB diagnoses and treatments: Findings from MSF/Epicentre At the World Conference on Lung Health held from November 18 to 21, 2025, in Copenhagen, Médecins Sans Frontières (MSF) and Epicentre have revealed that using the treatment decision algorithms recomme...

Just announced at #WCLH2025: WHO treatment decision algorithms could nearly double pediatric TB diagnoses and treatments.
This breakthrough could save thousands of lives—urgent adoption is needed.

epicentre.msf.org/en/news/who-...

Effect of prenatal multiple micronutrient supplements and medium-quantity lipid-based nutritional supplements on maternal weight gain and infant birth weight in rural Niger: a cluster-randomised trial Introduction The risk of adverse birth outcomes, such as low birth weight (<2500 g, LBW), is associated with poor maternal nutrition and weight gain in pregnancy and can increase the risk of infant mo...

Our study in BMJ Global Health assessed three prenatal nutrition strategies in rural Niger to improve maternal health and reduce adverse pregnancy outcomes.
Findings: no significant differences between approacheshttps://gh.bmj.com/content/10/11/e021013