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Posts by Anne Nichols

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πŸŽ“ Curious about a Graduate Degree in BME?
Join us for a virtual Grad Program Info Session!

πŸ“… Wed, Oct 15

πŸ”— Event Page: events.rochester.edu/event/bme-gr...

#BME #GradSchool #URochesterBME #MS #InfoSession #CMTI #BiomedicalEngineering @urochester.bsky.social @urengineering.bsky.social

6 months ago 3 2 0 1

1000000%! People forget (or don't like?) that good lab skills are a SKILL! skills take time to develop!

7 months ago 0 0 0 0

Can't wait, with working link now!!! 🀩🀩

7 months ago 3 0 0 0

Can't wait!! 🀩🀩

7 months ago 0 0 0 0

The link to register doesn't seem to work πŸ₯²

7 months ago 0 0 1 0
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Researchers Trace a Source of Poor Tendon Healing, Retrain Cells for a Better Recovery Long overlooked in the field of musculoskeletal study, the tendon is a highly complex anatomical structure that triggers a dynamic but mysterious cellular response when it's injured. In a new study in...

Great article about our recent study on epitenon cells in tendon healing out today in the @urmed.bsky.social newsroom!

www.urmc.rochester.edu/news/story/r...

#teamtendon #teamepitenon

8 months ago 3 2 0 0
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Epitenon-derived progenitors drive fibrosis and regeneration after flexor tendon injury in a spatially-dependent manner - Nature Communications The cell populations that contribute to healing and scar tissue formation following tendon injury are poorly defined. Here the authors show that cells originating from the tendon epitenon give rise to...

New #URochesterResearch in @natcomms.nature.com ⬇️

Led by Asst Professor of Orthopaedics Anne Nichols, PhD, the team uncovered the first direct evidence that epitenon cells play a key role in tendon healing and that removing them might actually improve recovery.

πŸ”— www.nature.com/articles/s41...

9 months ago 3 1 0 0

Finally, I don't know why we resist defining scientific research as a creative endeavor. Any scientist who has achieved some degree of professional success recognizes the creativity and the bursts of conceptual understanding that accompany major innovation.

1 year ago 110 26 5 7

Thanks Allison! Would love to hear your thoughts sometime!

9 months ago 0 0 0 0

Huge thanks to NIAMS for funding support, the reviewers who were fantastic, and my co-authors for all their help and support!

#teamtendon #teamepitenon

9 months ago 1 0 1 0
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Still a lot of super interesting questions, and a lot more to learn about these cells, but happy to finally have this piece out in the world despite all the hurdles (global pandemic, supply chain issues, drug shortages, the academic job market....)!

9 months ago 0 0 1 0
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Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.

9 months ago 0 0 1 0
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It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.

9 months ago 0 0 1 0
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Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.

9 months ago 0 0 1 0

This paper started as a wild hair- could I find a genetic driver that would let us trace epitenon cells during tendon healing? Short answer: yes. Long answer: YES beyond any of my initial hopes for the project. Huge thanks to my postdoc mentor Alayna Loiselle for encouraging me to chase this rabbit.

9 months ago 0 0 1 0
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Epitenon-derived progenitors drive fibrosis and regeneration after flexor tendon injury in a spatially-dependent manner Nature Communications - The cell populations that contribute to healing and scar tissue formation following tendon injury are poorly defined. Here the authors show that cells originating from the...

Our paper is out today in @natcomms.nature.com ! A short 🧡:

rdcu.be/eugVT

9 months ago 3 1 1 0

Huge thanks to NIAMS for funding support, the reviewers who were fantastic, and my co-authors for all their help and support!

#teamtendon #teamepitenon

9 months ago 0 0 0 0

Still a lot of super interesting questions, and a lot more to learn about these cells, but happy to finally have this piece out in the world despite all the hurdles (global pandemic, supply chain issues, drug shortages, the academic job market....)!

9 months ago 0 0 1 0
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Most exciting, targeted ablation of epitenon-derived cells improves functional recovery, suggesting they are a good target to improve tendon healing.

9 months ago 0 0 1 0
Post image

It ALSO turns out that mouse epitenon cells are really similar to the cells found in human peritendinous scar tissue, and express conserved markers that suggest shared function in mice and humans.

9 months ago 0 0 1 0
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Post image

Not only did we find a driver, but we used it to explore the origins and fates of epitenon cells. As it turns out, they contribute to both peritendinous adhesions and to the pool of new tenocytes that appear post-injury.

9 months ago 0 0 1 0

This paper started as a wild hare- could I find a genetic driver that would let us trace epitenon cells during tendon healing? Short answer: yes. Long answer: YES beyond any of my initial hopes for the project. Huge thanks to my postdoc mentor Alayna Loiselle for encouraging me to chase this rabbit.

9 months ago 0 0 1 0
Queen’s Special U.S. Doctoral Recruitment Initiative | School of Graduate Studies and Postdoctoral AffairsDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown... Queen’s University is a globally engaged, research-intensive institution dedicated to attracting and supporting exceptional PhD students who will significantly advance our research mission.

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy.
Details found hereπŸ‘‡

www.queensu.ca/grad-postdoc...

10 months ago 1906 1429 19 103
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Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans - Nature Cell Biology This Review discusses the diversity of human fibroblasts, including their embryonic origin and precursor populations, and highlights their crucial role in orchestrating organ function and modulating i...

And, apart from me announcing I am out of the office because of illness, should we talk about something more exciting? Anyone interested in human #fibroblasts and their roles in health and disease? Take a look at this Review we recently published in our journal!
πŸ‘‰https://rdcu.be/eqKaT
bit.ly/3Ztppa5

10 months ago 16 4 0 0

Today, my NIH colleagues and I did something scary but really important. We spoke up about egregious harms we are seeing happen to research participants and public health through thoughtless and politicized policies at NIH. 🧡1/3

apnews.com/article/nih-...

10 months ago 1040 254 36 20
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10 months ago 5 0 1 0
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11 months ago 2 0 0 0
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Join us on Tuesday, April 1 (6:00-7:00pm) in Goergen 108 to learn about the importance of prioritizing diversity, equity, inclusion, and accessibility in biomedical engineering!

#biomedicalengineering #diversity #inclusion #accessibility

1 year ago 2 1 0 0

I'm starting a project to help trainees (undergrads, graduates, or postdocs) in orthopaedic research who have been affected by recently terminated grants (e.g. diversity supplements). If you know someone affected, please send me the details. "Re-sky", pls! @orssociety.bsky.social @asbmr.bsky.social

1 year ago 15 6 0 1
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