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Posts by Marco Pessoa

It's nobody's fault of course but sometimes it feels even academics forget that papers from writing to publication usually take prob more than a year. And that's part of the whole point. Slower than frenetic news and slower than blog posts is good actually because it is required for the process.

2 days ago 67 6 1 1
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Genomic approaches to build de novo elite breeding gene pools from locally adapted landraces

Many nascent breeding programs cross locally‑elite lines but lack structured gene‑pool design. This study compares genomic approaches to infer elite gene pools, showing that QTL‑based inference plus iso‑elite crosses boosts genetic gain in simulated forward‑breeding programs.

2 days ago 3 1 0 0
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Astronomers have completed the largest 3D map of the universe ever made.

Learn more: https://scim.ag/4tTqtAF

6 days ago 61 14 3 0
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Some day I’ll figure out how to work this into a talk

6 days ago 201 23 4 4

Sounds interesting

1 week ago 0 1 0 0

Science is good. We should fund it.

1 week ago 12641 2531 135 65
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Digitally native species are a necessary shift in taxonomic practice Nature Reviews Biodiversity - Biodiversity science laments how little is known about the planet’s biodiversity, yet routinely discards much of the taxonomic evidence generated during species...

#Biodiversity science laments how little is known about the planet’s biodiversity, yet routinely discards much of the taxonomic evidence generated during species description. www.nature.com/articles/s44...

2 weeks ago 8 2 0 0
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Weekend spins 4/n

Marcos Valle - Jet-Samba (2005)
Rocinante, Três Selos, Dubas R3-058/TSPL-098
Brasil, 2024

#vinyl #bossanova #jazz

2 weeks ago 2 0 0 0
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Weekend spins 3/n

Mahavishnu Orchestra - Birds of Fire (1973)
Columbia KC 31996
US pressing, 1973

#vinyl #fusion

2 weeks ago 1 0 0 0
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Weekend spins 2/n

P J Harvey - Stories From the City, Stories from the Sea (2000)
Island Records #0898541
Reissue, 2021

#vinyl #record

2 weeks ago 1 0 0 0
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Weekend spins 1/n

John Abercrombie - Timeless
ECM Records #2301 047 (1975)
Brasil, Reissue, 1983

#vinyl #records #jazz #fusion #postbop

2 weeks ago 1 0 0 0
Phylogenetic Comparative Methods Phylogenetic Comparative Methods

Hi all. I am very excited that after 6 years I finally got my phylogenetic comparative methods book and online exercises online. Feel free to use and share. The book is here: nhcooper123.github.io/pcm-primer/. Note that it is not finished, we had to abandon it before the sunk costs fallacy broke us

4 weeks ago 286 180 9 3
A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

A full disc image of Earth, as seen from the Orion Crew Module. The planet is a pale blue, swirling with white clouds and glowing slightly lighter blue in place from reflected light. At lower left, a large brown landmass is Africa, with Spain and Portugal with twinkling lights where the planet curves. At top right, auroras glow in a thin green glow, just barely separated from the planet's surface. Earth is set against the black of space (pic: NASA/R.Wiseman)

More context on this #Artemis II image:

* This is the night side, lit by moonlight. You can see city lights in Spain & Portugal, & a sliver of day at lower right

* The Sun is entirely behind Earth, which makes it a kind of solar eclipse, but w/ Earth doing the eclipsing instead of the Moon:
☀️🌍🚀🌕

2 weeks ago 13119 3712 234 321
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The System That Decides What Science Gets Published Is Breaking Down The peer review system that validates scientific research is trapped in a self-defeating cycle. A new mathematical model shows why—and what comes next.

Some first-rate science writing: For this story, @jdrakephd.bsky.social carefully read our recent paper and then we spent a very fun 90 minutes or so talking on zoom. His article that gets right to the heart of our model, explains it clearly, and then explores why it will matter in the future.

3 weeks ago 279 114 9 10
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Highly accurate ab initio gene annotation with ANNEVO - Nature Methods ANNEVO advances accurate and scalable ab initio gene annotation of evolutionarily diverse genomes using deep learning approach modeling sequence evolution and long-range dependencies and mixture of ex...

www.nature.com/articles/s41...

3 weeks ago 0 0 0 0
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A whole‐genome assembly of St. Augustinegrass and visualizing diversity within the species The first chromosome-scale assemblies of both haplotypes of the Stenotaphrum secundatum genome were assembled. A total of 62,454 protein-coding genes were annotated across both haplotypes. A uniform...

acsess.onlinelibrary.wiley.com/doi/10.1002/...

3 weeks ago 0 0 0 0
A hand holding the record jacket of Damien Jurado's Brothers and Sisters of the Eternal Son, front cover, a ficus lyrata to the right, and a record stand with a turntable and a receiver to the left

A hand holding the record jacket of Damien Jurado's Brothers and Sisters of the Eternal Son, front cover, a ficus lyrata to the right, and a record stand with a turntable and a receiver to the left

A hand holding the record jacket of Damien Jurado's Brothers and Sisters of the Eternal Son, back cover, a ficus lyrata to the right, and a record stand with a turntable and a receiver to the left

A hand holding the record jacket of Damien Jurado's Brothers and Sisters of the Eternal Son, back cover, a ficus lyrata to the right, and a record stand with a turntable and a receiver to the left

Damien Jurado - Brothers and Sisters of the Eternal Son
Secretly Canadian, 2014 (SC295)

#vinyl #vinylcollector

3 weeks ago 2 0 0 0
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Google Has a Secret Reference Desk. Here's How to Use It. 40 Google features to find exactly what you need, the alternative search engines that do things Google won't, and the reference desk framework underneath all of it.

This is a great list of techniques for getting real information out of a Google search and avoiding AI slop and paid results.
(One thing not included is that if you add "-ai" to a search, you block the AI summary) cardcatalogforlife.substack.com/p/google-has...

1 month ago 2144 1015 57 112
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Operationalizing tropical plant genomics in Brazil Tropical regions harbor most of Earth’s plant diversity but remain under-represented in genomic resources. Using Brazil as a case study, we highlight …

This came out today. Glad to be part of it.

www.sciencedirect.com/science/arti...

1 month ago 0 0 0 0
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Excited so share our newest study using a single-library HiFi-CiFi approach to generate chromosome-scale diploid assemblies of two vole genomes, identifying putative drivers of divergent pair-bonding behavior, namely a prairie-vole-specific duplication of Avpr1a gene, led by @mabuelanin.bsky.social

1 month ago 31 17 2 2
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Brasília has its own Octagonal Sector

1 month ago 2 0 0 0

An issue we're seeing at all levels of university is that many students are simply refusing to do *anything*. They aren't reading the syllabus, aren't following assignment guidelines, aren't engaging with material, ignoring deadlines. And this might seem like old news, but it truly has ramped up.

4 months ago 5091 1179 260 839
Postdoctoral Research Fellowships - University of California Alianza MX Submitting an Application Current Fellows 2025 Cohort Additional Information Humberger Toggle Menu Interested in applying for a Postdoctoral Research Fellowship? Eligibility The program seeks applican...

¿Hiciste tu doctorado en México? ¿Quieres hacer un postdoc en California? ¿Te interesa la genética evolutiva? ¡Checa esta beca y mándame un mensaje! alianzamx.universityofcalifornia.edu/research-and...

5 months ago 20 25 0 1

Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.

7 months ago 394 126 6 15
Text from an FAQ in Okbay et al 20222: 
https://www.nature.com/articles/s41588-022-01016-z 
a similar same statement is made in an FAQ in 2025: https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1.supplementary-material
Text reads:
"The results of SSGAC studies have sometimes been used by online platforms, including some companies, to predict individual outcomes. We recognize that returning individual genomic “results” can be a fun way to engage people in research and other projects and to feed or stoke their interest in genomics. But it is important that participants/users understand that these individual results are not meaningful predictions and should be regarded essentially as entertainment. Failure to make this point clear risks sowing confusion and undermining trust in genetics research"

Text from an FAQ in Okbay et al 20222: https://www.nature.com/articles/s41588-022-01016-z a similar same statement is made in an FAQ in 2025: https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1.supplementary-material Text reads: "The results of SSGAC studies have sometimes been used by online platforms, including some companies, to predict individual outcomes. We recognize that returning individual genomic “results” can be a fun way to engage people in research and other projects and to feed or stoke their interest in genomics. But it is important that participants/users understand that these individual results are not meaningful predictions and should be regarded essentially as entertainment. Failure to make this point clear risks sowing confusion and undermining trust in genetics research"

It is depressing, but all too predictable, how swiftly we’ve gone from the Social Science Genetic Association Consortium offering reassurances about the uses of behavioural polygenic scores to one of their lead authors marketing embryo selection for IQ

8 months ago 214 83 8 8

Asking for a friend: Colleague was shipping purified RNA samples from Brazil to Macrogen Korea. She had a FedEx prepaid shipping label provided by Macrogen. FeDex returned shipment because this was a biological sample. Anyone else had an issue like this?

9 months ago 1 1 0 0

Asking for a friend: Colleague was shipping purified RNA samples from Brazil to Macrogen Korea. She had a FedEx prepaid shipping label provided by Macrogen. FeDex returned shipment because this was a biological sample. Anyone else had an issue like this?

9 months ago 1 1 0 0
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FastGA: Fast Genome Alignment www.biorxiv.org/content/10.1... 🧬🖥️🧪 www.github.com/thegenemyers...

10 months ago 26 9 1 1
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It may be true (I don't know enough neuroscience to say) that LLMs & human brains use similar techniques to make connections between concepts & learn. But most humans don't speak confidently & coherently about something unless they actually know it. The ones who do... well, we have words for them.

10 months ago 1189 79 51 25

I expect that consumer-facing AI programs will continue to improve and they may become much more useful tools for everyday life in the future.

But I think it was a disastrous mistake that today’s models were taught to be convincing before they were taught to be right.

10 months ago 8543 1394 286 149