In 2 randomized trials of Paxlovid there was lack of evidence of reduced hospitalizations among participants, who were age 50+ w/ coexisting conditions, and vaccinated.
The endpoint was very low in the treatment and control groups for both trials \https://nejm.org/doi/full/10.1056/NEJMoa2502457
open.substack.com/pub/robertre... “‘When presidential aides tell reporters that they’ve had to keep a president out of the room because they believed his impatience wouldn’t be helpful, what they’re really saying is they’re dealing with someone who’s so irrational they don’t trust his judgment.”
🤦♂️🤦♂️🤦♂️
open.substack.com/pub/robertre... “A direct line connects Trump’s attempted coup in 2020 and January 2021 to his capture of Maduro to his attack on Iran without congressional authority to his blatant corruption. All are lawless. All are premised on the hubris of omnipotence.”
#TrumpsMess
🤬🤬🤦♂️
The Texas legislature rammed through a gerrymandering bill at the request of Trump.
Virginia actually voted in favor of redistricting to counterbalance what Texas and other Republican-controlled states have done.
Yet only one is considered a "power grab."
Oligarch-owned media in a nutshell.
SPLC Indictment Reactions.. condemnation for this abusive, sloppy, incoherent indictment meant to save Kash's job and get Blanche the AG job permanently. Shame on ANYONE who had anything to do with this outrage open.substack.com/pub/contrari...
Who among us hasn't needed a SWAT-style wakeup call after a night at the Poodle Room? The latest on Kash Patel...
open.substack.com/pub/paulkrug... “asignificant number of Americans believed Trump’s impossible promises about the economic miracles he would conjure into being, but now realize that they were lied to. And, this can explain why Americans are so intensely angry and pessimistic about the economy now”🤬
Are the women back there somewhere? Yes, I think I see them.
Michael Kosta Introduces Former Labor Secretary Lori Chavez-DeRemer www.nytimes.com/2026/04/22/a... “What the hell? Was she going through her workplace anti-harassment training like, ‘Challenge accepted’?” — MICHAEL KOSTA
🤦♂️🤦♂️🤣
I need a strait of vermouth 🤦♂️🤦♂️
This is what caused Trump’s meltdown tonight.
With the VA yes vote, Democrats will emerge with +1 House seat in the redistricting wars Trump kicked off last summer. They are very, very likely to win back the House in November
Kevin Warsh told me he was "independent" and a "tough guy."
So I asked him to name just one aspect of President Trump's economic agenda that he disagrees with.
You'll never believe what he said.
White supremacist ideology
"Trump Is Said to Be in Talks to Send Afghans Who Aided U.S. Forces to Congo: A U.S. aid worker said that the Afghans, who were evacuated to Qatar, would face a choice between moving to the Democratic Republic of Congo and living under the Taliban." -- www.nytimes.com/2026/04/21/w...
When Trump talked about ushering in a "new golden age," he was talking about a new golden age for his family's pocketbook.
Trump is setting the USA back 20 years on affordable, reliable, geopolitical free energy all to satisfy his donors. Trump promised to scrap climate laws if US oil bosses donated $1bn – report www.theguardian.com/us-news/arti...
Influenza
Breaking News: President Trump is said to be in talks to send Afghans who helped the U.S. war effort to the Democratic Republic of Congo.
Fresh free link (they expire after 300).
as.ft.com/r/3cb9d0aa-9...
Trump also *hilariously* quips (again) that Kevin might need an office next to his in the White House
Elizabeth Warren nails Warsh right between the eyes: if you're tough and independent, did Donald Trump lose the election in 2020?
Warsh refused to answer, dances around the question. Won't matter to Republicans, but could raise questions in the markets about subservience.
His consistent inconsistencies, which you ably point out, are just mind numbing. The problem is that it’s the best thing I can say about him. 🤬🤦♂️
There's nothing normal about this season of Fed Chair Apprentice, and it is far from over. My preview of Kevin Warsh's confirmation hearing. stayathomemacro.substack.com/p/fed-chair-...
IRIB SAID NO IRANIAN DELEGATION, PRIMARY OR SECONDARY, HAD TRAVELED TO ISLAMABAD AND THAT REPORTS ABOUT THE DEPARTURE OF IRANIAN OFFICIALS, INCLUDING CLAIMS ABOUT MEETING TIMES, WERE NOT ACCURATE.
Kernen asks Trump if he'd drop the investigation of Powell in order to get Kevin Warsh seated on the Fed. Trump responds by ranting and raving about the Fed building renovation project and suggests Powell is taking a cut of proceeds.
The propsective Fed Chair refuses to say whether cutting interest rates 250bps would stimulate the economy and boost inflation
