Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila - EMBO Reports Organ functionality requires the precise coordination of diverse tissues during development. Halfway through Drosophila embryogenesis, two lateral epidermal sheets stretch to fuse at the dorsal midlin...

Yay! Our paper is now out @emboreports.org! I posted about it a while back (tinyurl.com/yc7td3px) but the work really improved thanks to the wonderful feedback from three anonymous reviewers 🙏 (1/4)

Thrilled to share that my former student, Alex Braun, has been awarded the Rainer Rudolph Prize 2024 for his master's thesis on designing artificial enzymes with language models! Immensely proud of him. A toast all the way from Mexico! 🎉👏🌟

Preprint: www.biorxiv.org/content/10.1...

Deciphering the folding code of collagens - Nature Communications Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism that employs salt bridge...

How does collagen fold? Very carefully! (And with some help from electrostatics.) Our latest collaborative study uncovers kinetic mechanisms where interchain electrostatic interactions act as molecular clamps to promote proper folding. Check it out! 🎉🌟🧬🧫

www.nature.com/articles/s41...

Deciphering the folding code of collagens Nature Communications - Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism...

Archea and bacteria have collagen-like proteins? I didn't know that! 🤯
Congrats @romeritos.bsky.social and everyone involved in this work!

Deciphering the folding code of collagens
rdcu.be/eed6e

Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila For organs to be functional, the cells and tissues that constitute them must effectively interact with each other and coordinate their behaviours. Halfway during Drosophila embryogenesis, two lateral ...

The first original research paper from my lab is now out in @biorxivpreprint.bsky.social! www.biorxiv.org/content/10.1...
Tracheal development is an amazing model to study morphogenesis. There are great works out there that show how this tissue elongates, interconnects, and forms branches (1/n)