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Navigating Mast Cell Activation Syndrome (MCAS) with Jess Lewis (Episode 122) Listen now | In this episode, Matt and Angela—joined by Jess Lewis—dive into the complexities of MCAS, exploring its links to autism, POTS, and the healing potential of functional medicine.

New podcast episode: I joined the Autistic Culture Podcast to talk MCAS, neurodivergence, and recovering from the chaos of Covid + mold + medical gaslighting.

It's a lot—but also hopeful.
🎧 www.autisticculturepodcast.com/p/navigating...

#MCAS #Autism #LongCovid #Neurodivergent

I have to be careful, too. The best white chocolate doesn't rely on sugar to give it flavor.

Also adding the in a lot of post-Covid PEM, the reaction to exercise is actually heat intolerance (causes histamine reactions) due to mast cell disregulation.

100% Chris Murphy too.

Same. They’ve lost me and any donations. We need a NEW Dem party with AOC and Pete at the front

Long Covid has stolen health, careers, and stability from millions. For many, it triggered MCAS, POTS, and unrelenting fatigue.

This is a mass disabling event, and we still don’t have the research or treatment we need.

We can’t let this fade into silence. #LongCovidAwarenessDay 💜

I have! Thank you. It was a difficult road but it led me back to my path so I’m grateful.

If you have #LongCovid symptoms that you have not been able to figure out how to get beyond and you're STILL suffering, there is a more than 75% chance you have Mast Cell Activation Syndrome. Yes. It's true. And I want you to stop suffering this alone and get better. There IS a way.

#MCAS

If you want to learn more about what foods are safe or what foods to start with when exploring a low-histamine diet, follow me and grab my food list. Link 🔗 in bio. (8/8)
#MCAS #HistamineIntolerance #LongCovid

Our bodies react not just to what we eat, but how it was processed before it ever reached our plate. Understanding histamine buildup in food can help us make better choices for stability and healing. Have you noticed differences in how you react to different meats? (7/8)
#MCAS #HistamineIntolerance

This also explains why some people tolerate chicken or fresh fish better than aged beef or deli meats—it’s not just the type of meat, but how it’s handled. If you’ve noticed a pattern with meat triggering symptoms, histamine accumulation might be the reason. (6/8)
#MCAS #HistamineIntolerance

If meat flares your symptoms:
✅ Opt for fresh cuts over ground meat.
✅ Choose pasture-raised or lower-stress slaughter methods when possible.
✅ Eat meat soon after purchasing to avoid buildup. (5/8)
#MCAS #HistamineIntolerance #LongCovid

🔹 Grinding & Processing: Increases surface area, exposing meat to more bacteria that can produce histamine.
🔹 Storage Time: The longer meat sits, the higher the histamine buildup.

This is why fresh, unprocessed meat is often better tolerated by people with histamine issues. (4/8)
#MCAS

This histamine doesn’t just disappear—it remains in the muscle tissue, meaning we consume those elevated levels. But stress isn’t the only factor. Processing methods also matter:
🔹 Aging & Dry-Aging: Allows histamine to accumulate over time. (3/8)
#MCAS #HistamineIntolerance #LongCovid

why some meats trigger flares while others don’t. When an animal is under high stress before slaughter, its body releases adrenaline and cortisol—both of which can activate mast cells and trigger a histamine surge. (2/8)
#MCAS #HistamineIntolerance #LongCovid

TW: Animal stress, food processing

Did you know that stress levels before slaughter can increase histamine levels in meat? And that ground or aged meats tend to have even more histamine buildup? If you have histamine intolerance or MCAS, this could explain 🧵 (1/8)
#MCAS #HistamineIntolerance

I still can’t believe he’s in charge

We have to be more vigilant than ever. More discerning. More vocal. Healthcare is already an uphill battle for us—this just made the slope even steeper.

Stay informed, stay engaged, & call bullshit when you see it. 2/2

RFK Jr. leading HHS is a fucking disaster.

For the disability, MCAS, & Long Covid communities, for medical research & public health—this is DANGEROUS. This man has pushed conspiracy theories over science for years, & now he’ll oversee the very systems that protect (or fail) us. 1/2

Now you've got me craving pineapple upside down cake. I made an almond olive oil version that was amazing. I am trying some modifications for those that are also low-oxalate.

I'm a BIG fan of pineapple on pizza - there's something about the savory/sweet mix that really hits it for me. I also just love hot pineapple (which I seem to tolerate far better than raw). Ever tried pineapple in fried rice???

MCAS recovery is frustrating because progress isn’t always linear. One day you’re thriving, the next, a mystery flare takes you out.

🔹 It’s not failure.
🔹 It is feedback.

Your body isn’t against you—it’s learning. Healing happens in patterns, not straight lines. Keep going. 💜

#MCAS #LongCovid

Me too - especially if it’s a good one. I also like “blonde” chocolate which is a caramelized variation that is still very histamine friendly but even tastier! Great for when I need a sweet treat

Roses are red, violets are blue, we can’t have chocolate… but white chocolate will do. 💔💜

Histamine intolerance means skipping milk/dark chocolate, but white chocolate? Technically low histamine. Controversial? Absolutely. Like pineapple on pizza. 🍕🍍

Love it? Hate it? Let’s hear it. 👀

#MCAS

We would love to have you join us! We have a decent size on FB but feel that moving off of Meta is best for everyone: community.mastcellsupport.com/invitation?c...

🔹 The nervous system: Dysregulation keeps mast cells hyperactive, leading to flares.
🔹 The result? Long Covid meets MCAS, and histamine intolerance skyrockets.

If this sounds familiar, you’re not alone but healing IS possible 2/2
#LongCovid

Did you know that viruses (like Covid 🦠) actually reshapes the body. It hits the gut, the nervous system, and for many, flips the mast cell switch into semi-permanent overdrive.

🔹 The gut: Viral damage disrupts DAO production, making it harder to break down histamine.
1/2
#MCAS

Fantastic that you’re feeling better. It’s super challenging for a lot of folks right now - lots of triggers of all kinds.