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Posts by JStark lab

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Our latest publication by @jessel-ap.bsky.social is out in @cp-cellreports.bsky.social. We show that DNA damage in late mitosis triggers an ATM-dependent increase in RNF126 and BRAP, which promote cell survival under these conditions.
With help from @rfreirelab.bsky.social
doi.org/10.1016/j.ce...

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🤣🤣

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Jeremy Stark Jeremy Stark, 48, passed away Thursday following a long battle with God.

WTF!!? 👀 Jeremy Stark — theonion.com/jeremy-stark/

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2026 DNA Damage, Mutation and Cancer Conference GRC The 2026 Gordon Research Conference on DNA Damage, Mutation and Cancer will be held in Ventura, California. Apply today to reserve your spot.

Check out the GRC for DNA damage and Cancer! Join us in Summy California for a week of DNA repair and Cancer! www.grc.org/dna-damage-m...

3 months ago 7 7 0 0
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217: Multiscale triads of meiotic crossover patterning ️Episode 217: Multiscale triads of meiotic crossover patterning In this episode of PaperCast Base by Base, we explore FFT and inverse-FFT analysis of Zip3/Zip2, Hop1 and Zip1 on yeast pachytene chromo...

basebybase.castos.com/episodes/mul...

4 months ago 1 2 0 0

Check them out at @basebybase.bsky.social

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53BP1-RIF1 and DNA-PKcs show distinct genetic interactions with diverse chromosomal break repair outcomes - Nature Communications DNA double strand breaks can be repaired by several pathways leading to different genetic outcomes. Here, the authors define the interplay between the DNA damage response factors 53BP1-RIF1 and core n...

Link to the paper www.nature.com/articles/s41... @natcomms.nature.com

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216: 53BP1-RIF1 and DNA-PKcs: distinct interactions in chromosomal break repair ️ Episode 216: 53BP1-RIF1 and DNA-PKcs: distinct interactions in chromosomal break repair In this episode of PaperCast Base by Base, we explore This episode reviews a study showing that 53BP1-RIF1 an...

Great summary and context of our recent study on this podcast. Even includes interpretive song. basebybase.castos.com/episodes/53b...

4 months ago 9 2 2 0

Check this out 👇👇👇

4 months ago 2 0 0 0
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53BP1-RIF1 and DNA-PKcs show distinct genetic interactions with diverse chromosomal break repair outcomes - Nature Communications DNA double strand breaks can be repaired by several pathways leading to different genetic outcomes. Here, the authors define the interplay between the DNA damage response factors 53BP1-RIF1 and core n...

New study from the lab on genetic relationship between 53BP1-RIF1 and DNA-PKcs on DSB repair outcomes. Led by PhD student @kaelamakins.bsky.social www.nature.com/articles/s41...

4 months ago 6 5 0 0

📢📢Apply now for GRS/GRC on DNA Damage Mutation & Cancer in sunny Ventura CA.

5 months ago 3 3 0 0

This data is really striking - mRNA vaccine priming ICI response in several tumors

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Kicking off No Kings Day with fired up patriots at NIH
Kicking off No Kings Day with fired up patriots at NIH YouTube video by Senator Chris Van Hollen

Today I kicked off No Kings Day with hundreds of fired up patriots at NIH who are standing up to this lawless president.

Together we said NO to his attacks on public health.
NO to his assault on our Constitution.
NO to kings in America.

And YES to standing up for our democracy.

6 months ago 1265 230 23 9
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No Kings! In Pasadena

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SoCal Genome Stability Symposium The annual Genome Stability Symposium provides a forum for trainees in the Southern California region to present their research on the field of genome stability.

Registration is open for the 2025 SoCal Genome Stability Symposium. Free registration. All talks by trainees. www.cityofhope.org/genome-stabi...

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Transcriptional repression facilitates RNA:DNA hybrid accumulation at DNA double-strand breaks - Nature Cell Biology Saur, Lesage et al. report that RNA:DNA hybrids arise at double-strand breaks in transcribed genes, independently of de novo recruitment of RNA polymerase II/III, as a result of DSB-induced transcriptional repression.

www.nature.com/articles/s41... saw @lablegube.bsky.social present this last week. Provides important clarity on RNA at chromosomal DSBs. Including rigorously debunking the nascent synthesis idea.

6 months ago 5 2 0 0
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Exciting to have 3 days to focus on this pathway.

6 months ago 2 0 0 0

It’s been a long time coming! Grateful to all co-authors and colleagues who supported this study, especially @yilanfan.bsky.social 🙌 We have been working on this complex for nearly 3 years together and finally managed to tame it. MRN gave us Many Restless Nights, but we’re More Relaxed Now 😎

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L1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangements www.biorxiv.org/content/10.1101/2025.09....

7 months ago 3 2 0 1
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I’m using this icon for my talk at nhej2025.sciencesconf.org
Guess the topic

7 months ago 3 0 2 0
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Gearing up to head to Paris for nhej2025.sciencesconf.org but indulging in some LA delicacies before I go.

7 months ago 2 0 0 0

I’ve met many raw milk is healthy, we already have the cure for cancer, immunizations are dangerous, HIV isn’t the cause of AIDS people. As a scientist I thought it important to counter with respect and logic, and wonder how we are failing at public health. No more. New response - “that’s stupid!”

7 months ago 2 0 0 0

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.

Descriptions and links in the following two posts.

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Image of Toronto

Image of Toronto

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

7 months ago 133 169 0 8
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Postdoctoral Training Programs Funded by the National Cancer Institute (T32CA186895), the program at City of Hope provides exceptionally motivated, recent (2 years or less) postdoctoral fellows with scientific knowledge, researc

We have openings for a postdoctoral training program on DNA Damage and Oncogenic Signaling. Our past trainees have been very successful. Apply by Aug 31 for full consideration. See link for details. www.imgs-coh.edu/postdoctoral...

8 months ago 7 6 0 0
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this is so wonderful and so critical right now

8 months ago 27 2 0 0
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Assistant Professor of Biochemistry at Vanderbilt University - Nashville, Tennessee job with Vanderbilt University School of Medicine | 12843515 Department of Biochemistry, School of Medicine—Basic Sciences

Advertisements for 2 tenure-track assistant professor positions at Vanderbilt School of Medicine Basic Sciences:
www.nature.com/naturecareer...
www.nature.com/naturecareer...

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Automated machine learning profiling with MAP-HR for quantifying homologous recombination foci in patient samples Abstract. Accurate visualization and quantification of homologous recombination (HR)-associated foci in readily available patient samples are critical for

Beyond BRCA status: machine-learning assisted multichannel imaging platform for cell-by-cell analysis of HR competency, enabling patient stratification. “Editor’s Choice” in NAR Cancer. academic.oup.com/narcancer/ar...

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NAR seeks a new Executive Editor Overview of the Journal Nucleic Acids Research (NAR) is a leading open access molecular biology journal published by Oxford University Press. It provides rapid

Our sister journal, Nucleic Acids Research, has opened a search for an Executive Editor. Great opportunity for mid-career or senior investigator looking to be part of a great team, handle 100-150 papers per year, and attend the annual EE meeting. Details at: academic.oup.com/nar/pages/ex...

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Fingers crossed 🤞

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