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Posts by Ben Hindson

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Conservative surgery and brachytherapy in pediatric bladder-prostate rhabdomyosarcoma: technical tips and tricks Bladder-prostate rhabdomyosarcoma (BP-RMS) is a rare pediatric malignancy. Historically, treatment involved radical surgery and or radiotherapy with i…

#medsky #pedsky #oncosky #pedsurgsky
@chirpedbicetre.medsky.social has just published a paper on combining surgery and brachytherapy for bladder-prostate rhabdomyosarcoma.
This technique used for 30 years till now, benefits to many children all over the world.
www.sciencedirect.com/science/arti...

8 months ago 4 2 0 0

a lot of people think you need a lot of money to buy clothes. now you're right. ok. my bad.

1 year ago 19637 1672 165 42
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Functional outcomes after primary vs delayed robot-assisted radical prostatectomy following active surveillance AbstractBackground. It is unknown if a period of active surveillance before prostatectomy for prostate cancer (PCa) worsens functional outcomes. The aim of

Functional outcomes after primary vs delayed robot-assisted radical prostatectomy following active surveillance

academic.oup.com/jncics/advan...

Suggest active surveillance doesntt have significant detrimental effect on functional outcomes, supportin for men w/low & favorable intermediate-risk PCa

1 year ago 4 3 0 0
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This article evaluates the overall survival (OS) and local recurrence (LR) in patients with grade 2 #meningiomas treated with adjuvant #radiotherapy compared to surgery alone at time of diagnosis.

Read more about their research: https://buff.ly/3ZUe43k

@syip.bsky.social

1 year ago 4 3 0 0
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Radiotherapy toxicities: mechanisms, management, and future directions For over a century, radiotherapy has revolutionised cancer treatment. Technological advancements aim to deliver high doses to tumours with increased precision while minimising off-target effects to or...

Check out this comprehensive and timely review in @lancet.bsky.social by our RadOnc group @PennMedicine.bsky.social on #radiotherapy related toxicities and the latest approaches to mitigate them. Congrats to @YiannisVerginadis.bsky.social who led this effort. www.thelancet.com/journals/lan...

1 year ago 13 6 1 0
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Exciting news! Our Red Journal invited editorial on sim-free RT is now available! @ijrobp.bsky.social @drdavidpalma.bsky.social
Grateful for the opportunity to contribute to this discussion! Check it out here: authors.elsevier.com/c/1kYHc1Hx52... #simfreeRT #radiotherapy #palliativeRT #OpenAccess

1 year ago 11 5 0 1

Word of day is ‘unasinous’ (17th century): united in stupidity.

A riff on ‘unanimous’: which comes from the Latin for ‘one mind’. ‘Unasinous’ means ‘one ass’.

1 year ago 7133 1912 184 204
Re: Creta, M., Shariat, S.F., Marra, G. et al. Local salvage therapies in patients with radio-recurrent prostate cancer following external beam radiotherapy: a systematic review and meta-analysis.  Prostate Cancer Prostatic Dis (2024). A. Pati-Alam, M. Fittall, J. Withington and S. Heavey.

Re: Creta, M., Shariat, S.F., Marra, G. et al. Local salvage therapies in patients with radio-recurrent prostate cancer following external beam radiotherapy: a systematic review and meta-analysis. Prostate Cancer Prostatic Dis (2024). A. Pati-Alam, M. Fittall, J. Withington and S. Heavey.

How does #prostatecancer recur after radiotherapy?

Alisha Pati-Alam, Susan Heavey and the team at UCL highlight this key question in their commentary of an important new meta-analysis on salvage therapies.

Grab a ☕and read more: doi.org/10.1038/s413...

1 year ago 6 3 0 1
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Decrease in Fracture Rate with Mandatory Bone-protecting Agents in the EORTC 1333/PEACE-3 Trial Comparing Radium-223 Combined with Enzalutamide Versus Enzalutamide Alone: A Safety Analysis Bone health is central to the management of patients with metastatic castration-resistant prostate cancer (mCRPC). International guidelines recommend …

#PEACE3 confirmed efficacy of combo of #Enzalutamide & #Ra223. For any treatment, safety & toxicity equally important. Read our recommendations on use of bone protection @eortc.bsky.social @mcrcnews.bsky.social @ccparker.bsky.social
👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽
www.sciencedirect.com/science/arti...

1 year ago 10 4 1 0
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Stereotactic Radiation Therapy for Localized Prostate Cancer: 10-Year Outcomes From Three Prospective Trials SABR is growingly accepted for the treatment of localized prostate cancer with recent randomized trials showing noninferiority compared with conventional or moderately hypofractionated radiation thera...

Stereotactic Radiation Therapy for Localized Prostate Cancer: 10-Year Outcomes From Three Prospective Trials out on the RedJournal

www.redjournal.org/article/S036...

Overall, SABR provides durable disease control for localized prostate cancer with manageable risks.

1 year ago 5 3 0 0

Spectacular results! Consolidation #radiotherapy for gallbladder cancer improves survival and maintains quality of life.
Congratulations to the study team.

1 year ago 13 7 0 0

Pts were excluded “if after radical prostatectomy they were considered by the investigator to be a candidate for salvage radiation therapy”. Hard to extrapolate omission from this dif pop… Want +MFS/OS w/PORT: S8794. What’s the cost of enza and would men rather yrs ADT or 5wk RT (w/o ADT for many).

1 year ago 6 1 1 0
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Efficacy and safety of prostate radiotherapy in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design Combining radiotherapy with standard of care plus abiraterone improves radiographic progression-free survival and castration resistance-free survival, but not overall survival in patients with low-vol...

PEACE-1 published
Radiotherapy of the prostate in metastatic pts prevents serious GU complications, in pts with low and high tumor burden

How to select patients?
- all ?
- based on live expectancy ?
- response to systemic Tx ?
- prostate volume ?

www.thelancet.com/journals/lan...

1 year ago 11 6 0 1
Post showing precipitous decline of share of deaths in Massachusetts from diseases for which vaccines are now available, from 70% in 1840 to low digits % by 1950-60 where it is stayed. 

Caption: There are not many places on earth where we have detailed cause-of-death data from before the era of widespread vaccination.

Massachusetts is one of those places.

From 1842-1877, 70% of all deaths were from diseases which we today have vaccines to prevent.

Post showing precipitous decline of share of deaths in Massachusetts from diseases for which vaccines are now available, from 70% in 1840 to low digits % by 1950-60 where it is stayed. Caption: There are not many places on earth where we have detailed cause-of-death data from before the era of widespread vaccination. Massachusetts is one of those places. From 1842-1877, 70% of all deaths were from diseases which we today have vaccines to prevent.

Anyone who is anti-vax is pro-death. Period. The science and data do not lie. And they don’t care about your podcast.

1 year ago 26345 5703 550 196

We “require “ MRI , TP systematic and target biopsy and PSMA correlation. Don’t always get all 3!

1 year ago 1 0 1 0

Hey #brachy #prostatecancer and #radonc. I’m interested to hear about what people are doing for prostate salvage #brachy? Focal or whole gland and what doses. We have done a few and I am writing a department protocol so any wise words ?

1 year ago 4 2 1 0
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Randomised Trial of No, Short-term, or Long-term Androgen Deprivation Therapy with Postoperative Radiotherapy After Radical Prostatectomy: Results from the Three-way Comparison of RADICALS-HD (NCT0054... The use and duration of androgen deprivation therapy (ADT) with postoperative radiotherapy (RT) have been uncertain. RADICALS-HD compared adding no (“…

Calmly updating our protocols when this is published #radonc
Who do I offer hormones to now ?

www.sciencedirect.com/science/arti...

1 year ago 3 0 0 0
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Randomised Trial of No, Short-term, or Long-term Androgen Deprivation Therapy with Postoperative Radiotherapy After Radical Prostatectomy: Results from the Three-way Comparison of RADICALS-HD (NCT0054... The use and duration of androgen deprivation therapy (ADT) with postoperative radiotherapy (RT) have been uncertain. RADICALS-HD compared adding no (“…

Overall fairly low risk group of participants, but helpful information to consider when counseling patients. Will be interesting to see what stratification will occur in the PSMA PET era.

Direct link to paper: www.sciencedirect.com/science/arti...

1 year ago 4 1 0 0

Nice to see the outcomes
Given other Radical publications - do we offer hormones to none or to the nasty ( and how to define ). ?

1 year ago 1 0 0 0

Searched and found on Netflix. Amazing documentary.

1 year ago 0 0 0 0

Nice one. Thanks. Good to slowly find more and more Radonc.

1 year ago 1 0 0 0

Could you add me please #radonc based in #Christchurch New Zealand
Paediatric and adult Radonc and #brachytherapy.

1 year ago 3 0 1 0