Our group just received a new R01 that was delayed by many months- it should have been awarded ‘25, like the curve below. This grant had the highest score we’d ever received (2%-ile), yet funding was uncertain. With the delay we had to lay people off. Very inefficient. And we are the lucky ones.
Please RT!
The Dept of Chemistry at UC Irvine invites applications for a tenured faculty position in Synthetic Organic Chemistry. Deadline: July 1, 2026.
More information about the position can be found here: recruit.ap.uci.edu/JPF10109
@uciphyssci.bsky.social
Every cycle, as 5 year grants awarded before 2024 start to term, we’ll be hearing the stories of labs shutting down.
In one ear, I’m hearing about all of the amazing successes of research initiated 10+ years ago at AACR. In the other, I’m reminded of the disastrous dismantling of the NIH.
Those of us doing research related to women’s health have been hit particularly hard by the govt’s sabotage of the NIH. I spoke to WaPo for this piece, as painful as it was to discuss the reality my lab is facing. www.washingtonpost.com/science/2026...
My impression is that the rank-and-file at NIH are working very hard and their hands have been tied.
bsky.app/profile/jere...
Thx!
The delay was in the awarding. Typically with a grant scoring well below the payline, you can predict when the award shoukf occur (like in the graph). They simply didn’t make awards for many months. Part of this was due to gov’t shutdown, but not all of the delay- perhaps OMB releasing funds late.
Our group just received a new R01 that was delayed by many months- it should have been awarded ‘25, like the curve below. This grant had the highest score we’d ever received (2%-ile), yet funding was uncertain. With the delay we had to lay people off. Very inefficient. And we are the lucky ones.
If any1 wants to try my very unpolished and unfinished TUI plasmid editor in its very pre-alpha form, I reserved a slot on the ol pip bandwagon. Just type in:
pip install splicecraft
and I recommend runnin this often to update:
pip install --upgrade splicecraft
It's a WIP 💚
Absolutely amazing.
When I started grad school there, Scripps hadn't conferred a single PhD and wasn't accredited.
My son is graduating college this year, which makes me positive: my folks must have thought I was insane.
Researchers invented a fake disease to test the spread of misinformation, and it worked a little too well. ChatGPT gave medical advice for 'bixonimania,' found in bogus preprints that thanked Starfleet Academy. They were only preprints, but it does highlight a significant area of concern.
#MedSky
I *really* like the Artemis II crew. At a moment when our nation is ruled by our worst it is inspiring to see some of our best at work.
They chose the name Integrity for their spacecraft. That speaks volumes.
CSR to continue the one-third triage cutoff for NIH grant review drugmonkey.wordpress.com/2026/04/06/c...
apple.news/A7pRmoOMpT72...
Sharing w/feedback to illustrate that there’s no ‘normal’ grief.
My take is different. I ignored calls after finding my spouse’s corpse. I’m stoic & taciturn, calls felt too demanding.
I appreciated texts, but what made me most grateful was any invitations to share a meal.
For sure, there is no normal grief. I appreciated texts, and meals, and calls, and generally any kind of help (w 2 kids) after losing a spouse. Initially the outpouring of support was significant, but after ~10 mos that started to fizzle. But grief doesn’t fizzle, it may just change its form.
Written by a multiple myeloma patient, who dug into the history behind revlimid’s discovery, and remarkable pricing history.
“ Rather than cutting or barely restoring funds, Congressional and administration leaders should commit to 10 years of steady increases in overall science funding of at least 6% per year. Over a dozen years, this would double the nominal dollar investment in science…”
🧪
Photo of Scripps pier, La Jolla, Ca
Scripps pier, La Jolla, Ca
Do you want cancer treatment improvements to continue: support fundamental research at NIH and NSF and its translational follow-up! Write Congress! 🧪
Written by a multiple myeloma patient, who dug into the history behind revlimid’s discovery, and remarkable pricing history.
Revlimid has its origin in a pill that cost patients $7.50 each.
Decades later, the cancer drug costs more than $18,000 for a month’s supply — even though it still only costs about 25 cents to manufacture.
(Published May 2025)
I’m amazed.
It’s really true: BA.3.2 (new COVID lineage) is infecting children at a much higher rate than previous lineages.
I’m late to this party, but I couldn’t really believe it was true until I did the analysis for myself.
1/
beautiful
Gosh. Maybe! I guess I better do a little more due diligence…
Well, it does say $400m in stock- but still- an 8 mo old preclinical company, even w milestones, at this value is pretty silly.
“ Rather than cutting or barely restoring funds, Congressional and administration leaders should commit to 10 years of steady increases in overall science funding of at least 6% per year. Over a dozen years, this would double the nominal dollar investment in science…”
🧪
New York Times article exploring the scientific brain drain to Europe.
[Gift link]
www.nytimes.com/2026/04/04/b...
This type of valuation in biotech would typically require one or more drugs deep in human clinical trials.
