#AACR2026 kicks off this weekend! Come find me at my posters!

🧪 Constitutive NRF2 activation drives excess cysteine stress

🗓️ April 19th, 2-5pm

📍Section 22, Board 3

🧪 Cysteine as a driver of resistance to Bortezomib

🗓️ April 20th, 9am-12pm

📍Section 16, Board 8

Just landed in Cincinnati for the first annual Future Faculty Conference hosted by the University of Cincinnati Cancer Center. Grateful for the invitation to grow my network, attend workshops for professional development, and meet with potential mentors and collaborators!

Drowning in cysteine - Nature Metabolism In this issue of Nature Metabolism, Brain, Vigil et al. show that NRF2-induced cystine uptake drives the formation of several cysteine–sugar metabolites. This process acts as a ‘sink’ for free cystein...

Also, check out this great N&V write up from the PapaG lab: www.nature.com/articles/s42...

Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?

Come chat with me at #AACR2026 @theaacr.bsky.social about this work or our next story! Excess cysteine stress: Poster #537 4/19 2-5pm Section 22, Board #3; Cysteine as a driver of resistance to Bortezomib: Poster #1788 4/20 9am-12pm, Section 16, Board #8.

Check out our latest work out today in @natmetabolism.nature.com in which we describe a new metabotype (metabolic phenotype): excess cysteine stress. We discovered novel cysteine conjugates and show how pyruvate modulates free intracellular cysteine levels. Grateful for an awesome team!!

Overjoyed to have the opportunity to present my work orally at the Cancer Metabolism Showcase! Hope to see you there virtually!

a cartoon of a man holding a frying pan and a spoon with red alert written above him ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him

ATTENTION: NSF GRANT RECIPIENTS

We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.

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Obliteride registeration opens today!!! Join the @lucasbsullivan.bsky.social team and help to CURE CANCER FASTER! See you August 9th at the starting line!! @obliteride.bsky.social #Obliteride #Obliteride2025 secure.fredhutch.org/goto/sulliva...

Poster is printed! Looking forward to going to the Keystone Tumor Metabolism meeting next week in Vancouver. Come talk to me about NRF2, cysteine, and novel metabolite discovery! #KSTumorMetab25 #cancermetabolism #keystonesymposia