Durable and efficient gene silencing in vivo by hit-and-run epigenome editing - Nature Experiments in mice show that designed epigenome editors that contain domains of transcriptional repressors can enable stable epigenetic silencing of Pcsk9, a gene with a role in cholesterol homeostas...

A mouse study in Nature demonstrates durable repression of a gene that has a role in controlling cholesterol levels, achieved without permanent genome editing. 🧪

Happy New Year from Sydney!

This resonated with me as I attempted to dust off the vocal cords for this carols season! Not the most attractive sounds. Will have to build up my muscles for next year!

A curious little possum made an appearance at the train station this morning after a late night out. I don't think I've ever seen one so bold in the daylight!