We’ll be sharing a detailed blog post in the coming days with everything that was built, discussed, and what comes next.

Stay tuned 🚀

A really great and in-depth summary by @heineikeb.bsky.social on our new paper where we dissect the genetics of multicellular-like phenotypes in fission yeast. It was truly a great project the work on, and strongly shaped me as a scientist. I never thought sticky yeast could be so cool! Thanks Ben!

Happy to share scHiCAR, an ultra-high throughout (millions of cells), low cost (5 cents/cell including NGS), and trimodal platform for integrated single-cell level analysis of mRNA, open chromatin, and 5-kb resolution looping with ground-truth data the same individual cell.

The $100 whole human genome sequence finally reached!
www.sandiegouniontribune.com/2026/02/19/s...

And unfortunately Wilcoxon remains what most people do in their standard scRNA-seq differential expression analysis between thousands of pseudoreplicates…

Not sure why @lpachter.bsky.social did not post this here. But it is brilliant. Single cell genomics finally makes it to the clinic.

The protein concentration in the cytoplasm is so high that the average protein has a water hydration shell with a thickness of only ≈ 10 water molecules separating it from the adjacent protein hydration shell.

1/2

Excited to release the Consensus Pituitary Atlas, which brings a shared framework to process, annotate, and analyze single-cell datasets in the mouse pituitary.
www.biorxiv.org/content/10.1...

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

It was really great to connect with people working on similar technologies and approaches. Looking forward to engaging more with the bioinformatics community in London.

After an overwhelmingly positive feedback from everyone at the meeting, I’m happy to have received the prize for “best talk” in the event. Many thanks to my supervisors (Cynthia Andoniadou and Grace Lu), my supportive labmates @pituitarylab.bsky.social, and of course the organisers of the event.

This Tuesday I attended the annual @londonomics.bsky.social symposium at the @crick.ac.uk , and presented a methods-focused version of some of the research I’ve done this past year.

Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project An analysis of TCGA whole-genome sequencing samples yields a comprehensive resource for investigating the role of microbes in cancer.

We're still not finding any good evidence for a microbiome in any cancer type: see our new paper in @ScienceTM led by PhD student Yuchen (Peter) Ge www.science.org/doi/10.1126/... and the accompanying news piece, www.science.org/content/arti...

1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬

www.science.org/doi/full/10....

Many thanks to the organisers, my supervisor Cynthia Andoniadou @pituitarylab.bsky.social and the other lab members (most of them without bluesky accounts) @jameskcl.bsky.social .

I was very happy to see a lot of people showing interest towards improving reproducibility and also trying out our online platform.

Specifically, I shared the work on our recently generated Consensus Pituitary Atlas built using all published 10x Genomics and Parse Biosciences single-cell pituitary samples, totalling nearly 1.1 million cells and 257 mice.

I had a great time presenting a poster of my research project at the Joint Congress of @esendocrinology.bsky.social and ESPE in Copenhagen.

Between serious research, our lab took some time out today for a fun hormone-themed activity.
Endocrinology escape room- all about hormones!
#BecauseHormonesMatter
#WorldHormoneDay
#pituitary #adrenal #endocrineresearch
@esendocrinology.bsky.social @ese-eyes.bsky.social @pituitaryorg.bsky.social

Tissue-like multicellular development triggered by mechanical compression in archaea The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...

Striking new study from @archaeon-alex.bsky.social's lab just out in @science.org on multicellular development induced by compression in Archaea: www.science.org/doi/10.1126/...

The more jargon you have in your paper the less citations you'll get.
royalsocietypublishing.org/doi/10.1098/...

David Baker talks about how the current uncertainty and instability hinder creativity because of the difficulty in thinking long-term. From this week’s Night Science Podcast nightscience.buzzsprout.com/1744020/epis... @nightsciencepod.bsky.social

I miss when the biggest controversy about mRNA was whether it correlated with protein or not.

Best lab with the best coffee mornings